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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 331906 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#331906, RRID:AB_1027671
- Product name
- Biotin anti-human CD335 (NKp46)
- Antibody type
- Monoclonal
- Antigen
- NKp46-Fc fusion protein
- Description
- CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis and is exclusively expressed on CD3-CD56+ NK cells, suggesting it to be a universal marker for NK cells. NKp46 along with NKp30 and NKp44 are referred to as natural cytoxicity receptors (NCR) and play a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C. Do not freeze.
Submitted references Activation of natural killer cells by newcastle disease virus hemagglutinin-neuraminidase.
Jarahian M, Watzl C, Fournier P, Arnold A, Djandji D, Zahedi S, Cerwenka A, Paschen A, Schirrmacher V, Momburg F
Journal of virology 2009 Aug;83(16):8108-21
Journal of virology 2009 Aug;83(16):8108-21
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes stained with 9E2 biotin, followed by Sav-PE
- Conjugate
- Biotin
