FNab05758

antibody from FineTest Biotech
Targeting: NLRP2 CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Provider product page for FNab05758
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab05758 - Provider product page
Provider
FineTest Biotech
Product name
NLRP2 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
NLR family, pyrin domain containing
2
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
NLRP2 protein structure - FNab05758 shown in red.