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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [5]
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- Product number
- PA5-52658 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- LHPP Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: LISLGKGRYY KETSGLMLDV GPYMKALEYA CGIKAEVVGK PSPEFFKSAL QAIGVEAHQA VMIGDDIVGD VGGAQRCGMR ALQVRTGKFR PSDEHHPEVK ADGYVD Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references LHPP impedes energy metabolism by inducing ubiquitin-mediated degradation of PKM2 in glioblastoma.
Chen WJ, Chen LH, Wang J, Wang ZT, Wu CY, Sun K, Ding BY, Liu N, Xu RX
American journal of cancer research 2021;11(4):1369-1390
American journal of cancer research 2021;11(4):1369-1390
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of LHPP in Lane 1: Marker (kDa) 230, 130, 95, 72, 56, 36, 28, 17, 11; Lane 2: Human cell line RT-4; Lane 3: Human cell line U-251MG sp; Lane 4: Human plasma (IgG/HSA depleted); Lane 5: Human liver tissue.; Lane 6: Human tonsil tissue. tissue. Samples were probed using a LHPP Polyclonal Antibody (Product # PA5-52658).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of LHPP in Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Samples were probed using a LHPP Polyclonal Antibody (Product # PA5-52658).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of LHPP in human cell line U-2 OS shows positivity in cytoplasm & nucleus but excluded from the nucleoli. Samples were probed using a LHPP Polyclonal Antibody (Product # PA5-52658).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of LHPP in human kidney using LHPP Polyclonal Antibody (Product # PA5-52658).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of LHPP in human testis using LHPP Polyclonal Antibody (Product # PA5-52658).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of LHPP in human liver using LHPP Polyclonal Antibody (Product # PA5-52658).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of LHPP in human colon using LHPP Polyclonal Antibody (Product # PA5-52658).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of LHPP in human hippocampus using a LHPP Polyclonal Antibody (Product # PA5-52658) shows strong nuclear and cytoplasmic positivity in glial cells.
