Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA5-64441 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HOXD4 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: ARAYSQSDPK QPPSGTALKQ PAVVYPWMKK V Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.2 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Prognostic significance of HOXD4 protein expression in human ovarian cancers.
Yu B, Guo X
Iranian journal of basic medical sciences 2021 Nov;24(11):1561-1567
Iranian journal of basic medical sciences 2021 Nov;24(11):1561-1567
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of HOXD4 in human cell line SK-MEL-30 using a HOXD4 Polyclonal Antibody (Product # PA5-64441) shows localization to nucleoplasm.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of HOXD4 in human epididymis using a HOXD4 Polyclonal Antibody (Product # PA5-64441) shows moderate nuclear positivity in glandular cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Expression of Homeobox D4 (HOXD4) in ovarian serous carcinoma (OSC) and adjacent tissues (A) RT-qPCR assays showed the mRNA levels of HOXD4 in OSC and adjacent nontumorous tissues (B) Representative high HOXD4 immunoreactivity in adjacent ovarian tissues (IHC score=12) (C) Representative low HOXD4 immunoreactivity in adjacent ovarian tissues (IHC score=1) (D) Representative high HOXD4 immunoreactivity in OSC tumor tissues (IHC score=12) (E) Representative low HOXD4 immunoreactivity in OSC tumor tissues (IHC score=0) (F) Immunohistochemistry (IHC) scores of HOXD4 in OSC tissues and paired adjacent tissues were summarized, which exhibited a higher average score in OSC tumor tissues (G) IHC scores of HOXD4 in patients with different FIGO stages were compared by one-way ANOVA test, indicating a positive correlation between HOXD4 and tumor progression