APR06928G

antibody from Leading Biology

Targeting: IL11 AGIF, IL-11

Western blot

Immunocytochemistry

Antibody data

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Validation data

Product number: APR06928G - Provider product page
Provider: Leading Biology
Product name: IL-11 Antibody
Antibody type: Polyclonal
Description: Interleukin 11 is a pleiotropic cytokine that has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6 (1). It directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (2). IL-11 promotes the proliferation of hepatocytes in response to liver damage. IL-11 binds to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 (3). Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelo-suppressive chemotherapy (4).
Reactivity: Human
Host: Rabbit
Isotype: IgG
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

IL11 protein structure - APR06928G shown in red.