RA0062

antibody from Oursmab

Targeting: CALCRL CGRPR, CRLR

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0062

Provider

Oursmab

Product name

Erenumab (Biosimilar Reference Antibody) (CALCRL)

Antibody type

Monoclonal

Description

Erenumab is a fully human monoclonal antibody specifically approved for the preventive treatment of migraine in adults. It belongs to a novel class of migraine-specific therapies known as calcitonin gene-related peptide (CGRP) pathway inhibitors. Erenumab functions as a selective and potent CGRP receptor antagonist. Unlike other CGRP inhibitors that target the ligand (the CGRP peptide itself), erenumab uniquely binds directly to the CGRP receptor, thereby preventing the CGRP peptide from activating the receptor complex. This blockade inhibits the downstream neuroinflammatory and vasodilatory signaling believed to be central to migraine initiation and propagation, leading to a reduction in migraine frequency and severity.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.