Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN1881739 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-RecQ Protein-Like 5 (RECQL5) (Center), (AA 662-691) antibody
- Antibody type
- Polyclonal
- Antigen
- This RECQL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 662-691 amino acids from the Central region of human RECQL5.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 662-691
- Antibody clone number
- RB39654
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Human RECQL5beta stimulates flap endonuclease 1.
RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase.
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity.
Direct inhibition of RNA polymerase II transcription by RECQL5.
A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin.
Speina E, Dawut L, Hedayati M, Wang Z, May A, Schwendener S, Janscak P, Croteau DL, Bohr VA
Nucleic acids research 2010 May;38(9):2904-16
Nucleic acids research 2010 May;38(9):2904-16
RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase.
Islam MN, Fox D 3rd, Guo R, Enomoto T, Wang W
Molecular and cellular biology 2010 May;30(10):2460-72
Molecular and cellular biology 2010 May;30(10):2460-72
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity.
Schwendener S, Raynard S, Paliwal S, Cheng A, Kanagaraj R, Shevelev I, Stark JM, Sung P, Janscak P
The Journal of biological chemistry 2010 May 21;285(21):15739-45
The Journal of biological chemistry 2010 May 21;285(21):15739-45
Direct inhibition of RNA polymerase II transcription by RECQL5.
Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ
The Journal of biological chemistry 2009 Aug 28;284(35):23197-203
The Journal of biological chemistry 2009 Aug 28;284(35):23197-203
A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin.
Aygün O, Svejstrup J, Liu Y
Proceedings of the National Academy of Sciences of the United States of America 2008 Jun 24;105(25):8580-4
Proceedings of the National Academy of Sciences of the United States of America 2008 Jun 24;105(25):8580-4
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- RECQL5 Antibody (Center) (ABIN1881739) western blot analysis in human Uterus tissue lysates (35 μg/lane). This demonstrates the RECQL5 antibody detected the RECQL5 protein (arrow).
