Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- MA5-11809 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-PTH1R Monoclonal Antibody (3D1.1)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- MA5-11809 targets Parathyroid Hormone Receptor Type 1 in IHC (P) and WB applications and shows reactivity with Human samples. The MA5-11809 immunogen is a 23 amino acid peptide of the hPTH/PTHrP receptor which is not shared by the type II receptor.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3D1.1
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Human parathyroid hormone-related protein and human parathyroid hormone receptor type 1 are expressed in human medulloblastomas and regulate cell proliferation and apoptosis in medulloblastoma-derived cell lines.
Gessi M, Monego G, Calviello G, Lanza P, Giangaspero F, Silvestrini A, Lauriola L, Ranelletti FO
Acta neuropathologica 2007 Aug;114(2):135-45
Acta neuropathologica 2007 Aug;114(2):135-45
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human breast carcinoma stained with PTH-R Type-1 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.