Antibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
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- Product number
- PA5-21479 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL12RB2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Predicted reactivity: Dog (80%), Pig (80%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references A short deletion in the DNA-binding domain of STAT3 suppresses growth and progression of colon cancer cells.
Xiong YJ, Liu DY, Shen RR, Xiong Y
Aging 2021 Feb 1;13(4):5185-5196
Aging 2021 Feb 1;13(4):5185-5196
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 3 STAT3 del reduces in vitro growth, survival and migration of colon cancer cells. ( A ) CCK8 assay results show the proliferation rate of SW480, SW620 and HCT-116 cells with wild type STAT3 or STAT3 del . ( B ) TUNEL assay results show the apoptotic rate of SW480, SW620 and HCT-116 cells with wild type STAT3 or STAT3 del . ( C ) Wound healing assay results show the migration rate of SW480, SW620 and HCT-116 cells with wild type STAT3 or STAT3 del . * denotes p