BS8519

antibody from Bioworld Technology, Inc
Targeting: DHPS MIG13
Provider product page for BS8519
Western blot
Immunohistochemistry

Antibody data

Product number
BS8519 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DHPS polyclonal antibody
Antibody type
Polyclonal
Antigen
Deoxyhypusine synthase; DHPS; DS
Description
Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DHPS protein structure - BS8519 shown in red.