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- References [146]
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- Product number
- 10957-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10957-1-AP, RRID:AB_2221670
- Product name
- ACOX1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ACOX1 antibody (Cat. #10957-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hypoxic Reprogramming of ACOX1-Driven HSP90AB1 Crotonylation Stabilizes Thioredoxin to Orchestrate Redox Homeostasis in Oral Squamous Cell Carcinoma.
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Apocrine carcinoma of the breast: distinctive metabolic reprogramming and high-frequency PIK3CA mutations revealed by molecular and immunohistochemical analysis.
Endothelial CEPT1 Promotes Angiogenesis Through PPARα and VEGF-A Signaling.
CTRP9 ameliorates heart failure with preserved ejection fraction by regulating lipid metabolism.
Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway.
Aging impairs peroxisome biogenesis in human B cells.
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy.
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells.
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Astragaloside IV delays vascular aging by enhancing mitochondrial fatty acid β-oxidation via the MLXIPL-PPARα/PGC-1α axis.
Strontium regulating lipid metabolism of bovine hepatocytes via SIRT1/SREBPs pathway.
Jiangtang Tiaozhi formula ameliorates MASLD by regulating liver ABCD2/PEX2/ATGL axis-mediated fatty acid metabolic reprogramming.
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery.
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
PPARα regulates acyl-CoA oxidase 1 (ACOX1) but not catalase.
PPARα activation attenuated heat-induced myocardial injury in mice.
TRIM59 deficiency aggravates HFD-induced obesity in mice associated with increased adipose tissue inflammation, lipid accumulation, and apoptosis.
ACAA1 knockout increases the survival rate of KPC mice by activating autophagy.
Fenofibrate alleviates sepsis-associated acute kidney injury by enhancing renal fatty acid oxidation.
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Macrophage CCL7 promotes resistance to immunotherapy for colorectal cancer by regulating the infiltration of macrophages and CD8(+) T cells.
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Bacterial pathogens hijack host cell peroxisomes for replication vacuole expansion and integrity.
Qishen Granules Modulate Metabolism Flexibility Against Myocardial Infarction via HIF-1 α-Dependent Mechanisms in Rats.
Qige Decoction attenuated non-alcoholic fatty liver disease through regulating SIRT6-PPARα-mediated fatty acid oxidation.
α-Lipoic Acid Ameliorates Arsenic-Induced Lipid Disorders by Promoting Peroxisomal β-Oxidation and Reducing Lipophagy in Chicken Hepatocyte.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injury.
Dose-response modeling of effects in mice after exposure to a polyfluoroalkyl substance (Nafion byproduct 2).
OTUB1 enhances fatty acid oxidation in APAP-induced liver injury by mediating ACSL5 deubiquitination.
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism.
ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer.
PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification.
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function.
Ribosome-binding protein 1 maintains peroxisome biogenesis.
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Exposure to submicroplastics promotes the progression of nonalcoholic fatty liver disease in ApoE-deficient mice.
Genetic algorithm-back propagation artificial neural network model- and response surface methodology-based optimization of crude Lophatherum gracile Brongn. polysaccharides extraction and their anti-NAFLD effects via regulating liver-adipose tissue crosstalk.
Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats.
NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease.
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration.
Gestational supplementation of Bifidobacterium, Lactobacillus, and Streptococcus thermophilus attenuates hepatic steatosis in offspring mice through promoting fatty acid β-oxidation.
Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.
Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia.
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease.
TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions.
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy.
Scoparone alleviates nonalcoholic fatty liver disease by modulating the PPARα signaling pathway.
Trivalent Chromium Ameliorates Lipid Accumulation and Enhances Glucose Metabolism in the High-NEFA Environment of Bovine Hepatocytes by Regulating PI3K/AKT Pathways.
Abnormal redox balance at membrane contact sites causes axonopathy in GDAP1-related Charcot-Marie-Tooth disease.
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
Hepatocyte-Specific PEX16 Abrogation in Mice Leads to Hepatocyte Proliferation, Alteration of Hepatic Lipid Metabolism, and Resistance to High-Fat Diet (HFD)-Induced Hepatic Steatosis and Obesity.
Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue.
Targeting nucleotide metabolic pathways in colorectal cancer by integrating scRNA-seq, spatial transcriptome, and bulk RNA-seq data.
Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features.
Acute murine cytomegalovirus infection boosts cell-type specific response and lipid metabolism changes in the liver of infant mice.
Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
TM4SF5-mediated abnormal food-intake behavior and apelin expression facilitate non-alcoholic fatty liver disease features.
Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.
Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice.
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Futile cycle of β-oxidation and de novo lipogenesis are associated with essential fatty acids depletion in lipoatrophy.
Proteomics reveals defective peroxisomal fatty acid oxidation during the progression of acute kidney injury and repair.
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Hepatic DKK1-driven steatosis is CD36 dependent.
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease.
A cottonseed oil-enriched diet improves liver and plasma lipid levels in a male mouse model of fatty liver.
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
MAPL loss dysregulates bile and liver metabolism in mice.
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis.
The Adaptive Characteristics of Cholesterol and Bile Acid Metabolism in Nile Tilapia Fed a High-Fat Diet.
Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARα Signaling Pathway.
Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice.
D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.
ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma.
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
FGF21 Reduces Lipid Accumulation in Bovine Hepatocytes by Enhancing Lipid Oxidation and Reducing Lipogenesis via AMPK Signaling.
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Elucidation of the mechanism of NEFA-induced PERK-eIF2α signaling pathway regulation of lipid metabolism in bovine hepatocytes.
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα.
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation.
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression.
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Impact of discontinuation of fish oil after pioglitazone-fish oil combination therapy in diabetic KK mice.
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression.
Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats.
Effect of selenium nanoparticles against abnormal fatty acid metabolism induced by hexavalent chromium in chicken's liver.
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.
miR-222 targets ACOX1, promotes triglyceride accumulation in hepatocytes.
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2.
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase.
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation.
p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure.
SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p.
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice.
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration.
Dietary nicotinic acid supplementation ameliorates chronic alcohol-induced fatty liver in rats.
Expressional studies of the aldehyde oxidase (AOX1) gene during myogenic differentiation in C2C12 cells.
Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice.
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation.
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Yin X, Zhang Y, Zhang Y, Zhou M, Zhang J, Wang Z, Xu W, Song C, Ran J, Lin L, Luo X, Han W
Research (Washington, D.C.) 2026;9:1129
Research (Washington, D.C.) 2026;9:1129
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Liang Q, Wang Y, Zhang X, Guo D, Qu G, Sun N, Xu J, Niu X, Liu Y, Geng J, Luo H, Wang C, Xin M, Wang X, Li Y, Jin F, Hu L
Free radical biology & medicine 2026 May;248:469-484
Free radical biology & medicine 2026 May;248:469-484
Apocrine carcinoma of the breast: distinctive metabolic reprogramming and high-frequency PIK3CA mutations revealed by molecular and immunohistochemical analysis.
Nakamura H, Kukita Y, Kittaka N, Kusama H, Nakayama T, Tamaki Y, Yoshida KI, Kunimasa K, Imamura F, Yagi T
Histopathology 2026 Mar;88(4):790-809
Histopathology 2026 Mar;88(4):790-809
Endothelial CEPT1 Promotes Angiogenesis Through PPARα and VEGF-A Signaling.
Khan TJ, Meade R, Elizondo-Benedetto S, Belaygorod L, Saffaf O, Rusconi B, Hsu FF, Adak S, Arif B, Zaghloul MS, Li T, Zhang B, Semenkovich CF, Zayed MA
Arteriosclerosis, thrombosis, and vascular biology 2026 Jan;46(1):195-209
Arteriosclerosis, thrombosis, and vascular biology 2026 Jan;46(1):195-209
CTRP9 ameliorates heart failure with preserved ejection fraction by regulating lipid metabolism.
Xin J, Liu R, Deng M, Song Y, Cui Y, Gao J, Zhang B, Feng L, Mu X, Cui J, Li H, Zhu L, Sun Y, Yi W
Journal of translational medicine 2026 Jan 7;24(1):228
Journal of translational medicine 2026 Jan 7;24(1):228
Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway.
Wang P, Du K, Tian Y, Qiao X, Yang Y, Zheng G, He W, Kang J, Zhang J, Zhang Z, Feng F, Zheng J
Cancer cell international 2026 Jan 27;26(1):98
Cancer cell international 2026 Jan 27;26(1):98
Aging impairs peroxisome biogenesis in human B cells.
Correia J, Roy PS, Holden KG, Kohut ML, Bai H
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Jan 12;81(2)
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Jan 12;81(2)
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy.
Niu Z, Yan Y, Liu W, Yao Q, Chen J, Shen S, Yu J, Ma M, Li Z, Wu Y, Li Y, Hu C, Zeng H, Gao X, Li Y, Jiang J, Ying H
Life metabolism 2026 Feb;5(1):loaf038
Life metabolism 2026 Feb;5(1):loaf038
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells.
Feng H, Li Z, Zhang H, Zheng Y, Xu B, Zhang Y, Zou L, Wu L
Nucleic acids research 2026 Feb 5;54(4)
Nucleic acids research 2026 Feb 5;54(4)
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Li Q, Zhang Y, Yu T, Shi L, Qiu Q, Wang B, Sang Y, Li R, Lv Q, Wang J, Liu X, Geng H, Jones PM, Liang J, Xu W
Islets 2026 Dec 31;18(1):2633793
Islets 2026 Dec 31;18(1):2633793
Astragaloside IV delays vascular aging by enhancing mitochondrial fatty acid β-oxidation via the MLXIPL-PPARα/PGC-1α axis.
Chen X, Chen X, Xiao N, Yang Y, Li C, Pan Y, Huang H, Duan X, Deng Y, Chen C, Zeng S, Yang S, Huang Y, Huang D, Yang Y, Shu Z, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158183
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158183
Strontium regulating lipid metabolism of bovine hepatocytes via SIRT1/SREBPs pathway.
Zeng F, Hu W, Xu H, Wang X, Zhao C, Wang Y, Wang J
The Journal of steroid biochemistry and molecular biology 2025 Sep;252:106785
The Journal of steroid biochemistry and molecular biology 2025 Sep;252:106785
Jiangtang Tiaozhi formula ameliorates MASLD by regulating liver ABCD2/PEX2/ATGL axis-mediated fatty acid metabolic reprogramming.
Miao R, Zhang Y, Zhang Y, Fang X, Yin R, Tian J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157032
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157032
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery.
Shi F, Wang S, Wu C, Wen H, Zhou W
International immunopharmacology 2025 Sep 23;162:115145
International immunopharmacology 2025 Sep 23;162:115145
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Li T, Yao Z, Huang Y, Li R, Zhang L, Chen R, Gu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
PPARα regulates acyl-CoA oxidase 1 (ACOX1) but not catalase.
Chen X, Mazur A, Xu W, Risher WC, Denning KL, Lu Y
Biochemical and biophysical research communications 2025 Sep 1;777:152247
Biochemical and biophysical research communications 2025 Sep 1;777:152247
PPARα activation attenuated heat-induced myocardial injury in mice.
Hu Z, Zhao L, Ma X, Li R, Qin L, Zhang L, Hou T, Zhang G, Liu C
Ecotoxicology and environmental safety 2025 Sep 1;302:118520
Ecotoxicology and environmental safety 2025 Sep 1;302:118520
TRIM59 deficiency aggravates HFD-induced obesity in mice associated with increased adipose tissue inflammation, lipid accumulation, and apoptosis.
Chen Y, Han X, Liu T, Ni Y, Deng X, Wei W, Jiang M
Cellular signalling 2025 Oct;134:111954
Cellular signalling 2025 Oct;134:111954
ACAA1 knockout increases the survival rate of KPC mice by activating autophagy.
Lee H, Kang M, Sim SH, Kang JH, Choi W, Chun JW, Hong W, Kim C, Ham W, Park JH, Koh EB, Jeon Y, Woo SM, Kim SY
Molecular metabolism 2025 Oct;100:102237
Molecular metabolism 2025 Oct;100:102237
Fenofibrate alleviates sepsis-associated acute kidney injury by enhancing renal fatty acid oxidation.
Zeng S, Wang J, Guan C, Yao Z, Zhang Y, Li Y, Zheng J, Wang H
BMC pharmacology & toxicology 2025 Oct 7;26(1):160
BMC pharmacology & toxicology 2025 Oct 7;26(1):160
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Yao H, Li L, Dai Q, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Macrophage CCL7 promotes resistance to immunotherapy for colorectal cancer by regulating the infiltration of macrophages and CD8(+) T cells.
Chen Y, Liu X, Chen J, Kuang L, Zhang N, Li D, Zhao D, Xue D, Lei J, Zhang J, Li Y, Wu L
Journal for immunotherapy of cancer 2025 Nov 24;13(11)
Journal for immunotherapy of cancer 2025 Nov 24;13(11)
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Xian JY, Peng L, Long J, Chen XW, Huang LH, Sun XY
Urolithiasis 2025 Nov 18;53(1):222
Urolithiasis 2025 Nov 18;53(1):222
Bacterial pathogens hijack host cell peroxisomes for replication vacuole expansion and integrity.
Hossain MJ, Romanov KA, Jian J, Swaby LC, Bandyopadhyay S, Guan I, Thomas SM, Olive AJ, O'Connor TJ
Science advances 2025 May 2;11(18):eadr8005
Science advances 2025 May 2;11(18):eadr8005
Qishen Granules Modulate Metabolism Flexibility Against Myocardial Infarction via HIF-1 α-Dependent Mechanisms in Rats.
Sun XQ, Li X, Li YQ, Lu XY, Liu XN, Cui LW, Wang G, Zhang M, Li C, Wang W
Chinese journal of integrative medicine 2025 Mar;31(3):215-227
Chinese journal of integrative medicine 2025 Mar;31(3):215-227
Qige Decoction attenuated non-alcoholic fatty liver disease through regulating SIRT6-PPARα-mediated fatty acid oxidation.
Fan S, Chen W, Li Y, Guo K, Tang H, Ye J, Zhou Z, Tan M, Wei H, Huang X, Huang K, Ke X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156395
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156395
α-Lipoic Acid Ameliorates Arsenic-Induced Lipid Disorders by Promoting Peroxisomal β-Oxidation and Reducing Lipophagy in Chicken Hepatocyte.
Zhao Y, Guo M, Pei T, Shang C, Chen Y, Zhao L, Lu Y, Liang C, Wang J, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2413255
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2413255
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
Zhang C, Chen L, Jiang Y, Qiu J, Lin Y, Ren G, Xu F, Xi J, Yu Z, Rong X, Dou X
International immunopharmacology 2025 Jun 5;157:114768
International immunopharmacology 2025 Jun 5;157:114768
N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injury.
Ying W, Weng W, Wang P, Pan C, Qiu J, Huang Q, Zhan G, Chen X
Journal of neuroinflammation 2025 Jun 27;22(1):167
Journal of neuroinflammation 2025 Jun 27;22(1):167
Dose-response modeling of effects in mice after exposure to a polyfluoroalkyl substance (Nafion byproduct 2).
Corton JC, Gift JS, Auerbach SS, Liu J, Das KP, Ren H, Lang JR, Chernoff N, Lau C, Hill D
Toxicological sciences : an official journal of the Society of Toxicology 2025 Jun 1;205(2):380-400
Toxicological sciences : an official journal of the Society of Toxicology 2025 Jun 1;205(2):380-400
OTUB1 enhances fatty acid oxidation in APAP-induced liver injury by mediating ACSL5 deubiquitination.
Guo S, Zhao Y, Wang Y, Lin M, Luan Q, Hu Z, Zhao X, Tian X, Wang Z, Yao J
Biochemical pharmacology 2025 Jul;237:116957
Biochemical pharmacology 2025 Jul;237:116957
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism.
Yuan T, Ye Z, Mei S, Zhang M, Wu M, Lin F, Yu W, Li W, Zhou X, Cheng F
Cell death & disease 2025 Jul 31;16(1):579
Cell death & disease 2025 Jul 31;16(1):579
ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer.
Shi B, Chen J, Guo H, Shi X, Tai Q, Chen G, Yao H, Mi X, Zhong R, Lu Y, Zhao Y, Sun L, Zhou D, Yao Y, He S
Scientific reports 2025 Jan 23;15(1):2992
Scientific reports 2025 Jan 23;15(1):2992
PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification.
Zhou W, Zhang S, Chen Y, Chen Z, Bi G, Guo M, Jiang X, Yang X, Fang J, Ye L, Fan S, Bi H
BMC biology 2025 Feb 28;23(1):64
BMC biology 2025 Feb 28;23(1):64
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function.
Li X, Hu Y, Li J, Shi Y, Zhong Q, Ma X, Jiang D, Zhang S, Zhuang S, Liu N
Renal failure 2025 Dec;47(1):2561218
Renal failure 2025 Dec;47(1):2561218
Ribosome-binding protein 1 maintains peroxisome biogenesis.
Fatima K, Vihinen H, Akpinar A, Somborac T, Paatero A, Jokitalo E, Paavilainen V, Katajisto P, Konovalova S
Journal of cell science 2025 Dec 15;138(24)
Journal of cell science 2025 Dec 15;138(24)
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L
Journal of translational medicine 2025 Dec 11;24(1):71
Journal of translational medicine 2025 Dec 11;24(1):71
Exposure to submicroplastics promotes the progression of nonalcoholic fatty liver disease in ApoE-deficient mice.
Li Q, Niu X, Cai Y, Li L, Xia Z
Toxicology 2025 Aug;515:154137
Toxicology 2025 Aug;515:154137
Genetic algorithm-back propagation artificial neural network model- and response surface methodology-based optimization of crude Lophatherum gracile Brongn. polysaccharides extraction and their anti-NAFLD effects via regulating liver-adipose tissue crosstalk.
Wu C, Chen QC, Ni Q, Cai WF, Jiang CP, Yi YK, Liu L, Shen CY
International journal of biological macromolecules 2025 Aug;320(Pt 1):145806
International journal of biological macromolecules 2025 Aug;320(Pt 1):145806
Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats.
Saito T, George J, Ozaki K, Tsuchishima M, Tsutsumi M
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):145
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):145
NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease.
Wu YC, Yan Q, Yue SQ, Pan LX, Yang DS, Tao LS, Wei ZY, Rong F, Qian C, Han MQ, Zuo FC, Yang JF, Xu JJ, Shi ZR, Du J, Chen ZL, Xu T
International journal of biological sciences 2024;20(6):2219-2235
International journal of biological sciences 2024;20(6):2219-2235
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
Yang Y, Yuan W, He K, Lin C, Du S, Kou Y, Nie B
Frontiers in pharmacology 2024;15:1366479
Frontiers in pharmacology 2024;15:1366479
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Zheng M, Zhang S, Zhou J, Lin M, Liao Y
Translational oncology 2024 Sep;47:102043
Translational oncology 2024 Sep;47:102043
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Choi J, Smith DM, Lee YJ, Cai D, Hossain MJ, O'Connor TJ, Deme P, Haughey NJ, Scafidi S, Riddle RC, Wolfgang MJ
iScience 2024 Sep 20;27(9):110642
iScience 2024 Sep 20;27(9):110642
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
Zhang W, Cheng Q, Yin L, Liu Y, Chen L, Jiang Z, Jiang X, Qian S, Li B, Wu M, Yin X, Wang T, Lu Q, Yang T
Chemico-biological interactions 2024 Sep 1;400:111157
Chemico-biological interactions 2024 Sep 1;400:111157
Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration.
Guo X, Zhou J, La Yan, Liu X, Yuan Y, Ye J, Zhang Z, Chen H, Ma Y, Zhong Z, Luo G, Chen H
Developmental cell 2024 Nov 18;59(22):3008-3024.e8
Developmental cell 2024 Nov 18;59(22):3008-3024.e8
Gestational supplementation of Bifidobacterium, Lactobacillus, and Streptococcus thermophilus attenuates hepatic steatosis in offspring mice through promoting fatty acid β-oxidation.
Chen H, Wu Q, Chen X, Yu X, Zhao H, Huang Q, Huang Y, Wang J, Huang X, Wei J, Wu F, Xiao X, Wang L
Journal of food science 2024 May;89(5):3064-3077
Journal of food science 2024 May;89(5):3064-3077
Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.
Wang C, Zeng W, Wang L, Xiong X, Chen S, Huang Q, Zeng G, Huang Q
Drug development research 2024 Jun;85(4):e22213
Drug development research 2024 Jun;85(4):e22213
Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.
Ding Z, Wei Y, Dai J, Pan C, Yang L, Li Q, Zhang Y, Yan Q, Wu C, Li A, Lan Z, Liu S, Wang X
Journal of translational medicine 2024 Jun 6;22(1):544
Journal of translational medicine 2024 Jun 6;22(1):544
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Dong S, Zhang M, Cheng Z, Zhang X, Liang W, Li S, Li L, Xu Q, Song S, Liu Z, Yang G, Zhao X, Tao Z, Liang S, Wang K, Zhang G, Hu S
Redox biology 2024 Jul;73:103207
Redox biology 2024 Jul;73:103207
ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia.
Tannoury M, Ayoub M, Dehgane L, Nemazanyy I, Dubois K, Izabelle C, Brousse A, Roos-Weil D, Maloum K, Merle-Béral H, Bauvois B, Saubamea B, Chapiro E, Nguyen-Khac F, Garnier D, Susin SA
Leukemia 2024 Feb;38(2):302-317
Leukemia 2024 Feb;38(2):302-317
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease.
Li L, Kong L, Xu S, Wang C, Gu J, Luo H, Meng Q
Hepatology international 2024 Feb;18(1):188-205
Hepatology international 2024 Feb;18(1):188-205
TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions.
Manandhar L, Dutta RK, Devkota P, Chhetri A, Wei X, Park C, Kwon HM, Park R
Cell communication and signaling : CCS 2024 Feb 21;22(1):142
Cell communication and signaling : CCS 2024 Feb 21;22(1):142
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
Pang J, Yin L, Jiang W, Wang H, Cheng Q, Jiang Z, Cao Y, Zhu X, Li B, Qian S, Yin X, Wang T, Lu Q, Yang T
Cellular signalling 2024 Dec;124:111478
Cellular signalling 2024 Dec;124:111478
Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy.
Zhang Y, Zhou J, Yang L, Xiao H, Liu D, Kang X
Antioxidants (Basel, Switzerland) 2024 Dec 9;13(12)
Antioxidants (Basel, Switzerland) 2024 Dec 9;13(12)
Scoparone alleviates nonalcoholic fatty liver disease by modulating the PPARα signaling pathway.
Huang P, Yang L, Liu T, Jiang Y, Chen Z, Song H, Zheng P
European journal of pharmacology 2024 Dec 5;984:177033
European journal of pharmacology 2024 Dec 5;984:177033
Trivalent Chromium Ameliorates Lipid Accumulation and Enhances Glucose Metabolism in the High-NEFA Environment of Bovine Hepatocytes by Regulating PI3K/AKT Pathways.
Wen Y, Mei L, Yang D, Zeng Y, Zhao C, Wang Y, Wang J
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26898-26914
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26898-26914
Abnormal redox balance at membrane contact sites causes axonopathy in GDAP1-related Charcot-Marie-Tooth disease.
Cantarero L, Roldán M, Rodríguez-Sanz M, Mathison AJ, Díaz-Osorio Y, Pijuan J, Frías M, Urrutia R, Hoenicka J, Palau F
Research square 2024 Dec 31;
Research square 2024 Dec 31;
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
Zheng Y, Wang Y, Xiong X, Zhang L, Zhu J, Huang B, Liu X, Liu J, Zhu Z, Yang G, Qu H, Zheng H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
Hepatocyte-Specific PEX16 Abrogation in Mice Leads to Hepatocyte Proliferation, Alteration of Hepatic Lipid Metabolism, and Resistance to High-Fat Diet (HFD)-Induced Hepatic Steatosis and Obesity.
Chen X, Wang L, Denning KL, Mazur A, Xu Y, Wang K, Lawrence LM, Wang X, Lu Y
Biomedicines 2024 Apr 30;12(5)
Biomedicines 2024 Apr 30;12(5)
Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue.
Liu M, He L
Cellular and molecular life sciences : CMLS 2024 Apr 22;81(1):190
Cellular and molecular life sciences : CMLS 2024 Apr 22;81(1):190
Targeting nucleotide metabolic pathways in colorectal cancer by integrating scRNA-seq, spatial transcriptome, and bulk RNA-seq data.
Zhao S, Zhang P, Niu S, Xie J, Liu Y, Liu Y, Zhao N, Cheng C, Lu P
Functional & integrative genomics 2024 Apr 10;24(2):72
Functional & integrative genomics 2024 Apr 10;24(2):72
Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features.
Mo Y, Zhao J, Zhao R, Huang Y, Liang Z, Zhou X, Chu J, Pan X, Duan S, Chen S, Mo L, Huang B, Huang Z, Wei J, Zheng Q, Luo W
Open life sciences 2023;18(1):20220696
Open life sciences 2023;18(1):20220696
Acute murine cytomegalovirus infection boosts cell-type specific response and lipid metabolism changes in the liver of infant mice.
Gao J, Wang A, Bu X, Jia W
Frontiers in immunology 2023;14:1169869
Frontiers in immunology 2023;14:1169869
Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
Yamashita A, Ignatenko O, Nguyen M, Lambert R, Watt K, Daneault C, Robillard-Frayne I, Topisirovic I, Rosiers CD, McBride HM
Biology direct 2023 Sep 22;18(1):60
Biology direct 2023 Sep 22;18(1):60
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
He Y, Kaya I, Shariatgorji R, Lundkvist J, Wahlberg LU, Nilsson A, Mamula D, Kehr J, Zareba-Paslawska J, Biverstål H, Chergui K, Zhang X, Andren PE, Svenningsson P
Nature communications 2023 Sep 19;14(1):5804
Nature communications 2023 Sep 19;14(1):5804
TM4SF5-mediated abnormal food-intake behavior and apelin expression facilitate non-alcoholic fatty liver disease features.
Pinanga YD, Lee HA, Shin EA, Lee H, Pyo KH, Kim JE, Lee EH, Kim W, Kim S, Kim HY, Lee JW
iScience 2023 Sep 15;26(9):107625
iScience 2023 Sep 15;26(9):107625
Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.
Yao Z, Xu N, Shang G, Wang H, Tao H, Wang Y, Qin Z, Tan S, Feng J, Zhu J, Ma F, Tian S, Zhang Q, Qu Y, Hou J, Guo J, Zhao J, Hou Y, Ding C
Nature communications 2023 Sep 13;14(1):5670
Nature communications 2023 Sep 13;14(1):5670
Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice.
Elmansi AM, Miller RA
GeroScience 2023 Oct;45(5):2967-2981
GeroScience 2023 Oct;45(5):2967-2981
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis.
Gui Y, Wang Y, Palanza Z, Wang JL, Gupta P, Tao J, Qiao Y, Hargis G, Kreutzer DL, Bastacky SI, Yu Y, Wang Y, Liu S, Fu H, Zhou D
Molecular metabolism 2023 May;71:101712
Molecular metabolism 2023 May;71:101712
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
Futile cycle of β-oxidation and de novo lipogenesis are associated with essential fatty acids depletion in lipoatrophy.
Chaves-Filho AB, Peixoto AS, Castro É, Oliveira TE, Perandini LA, Moreira RJ, da Silva RP, da Silva BP, Moretti EH, Steiner AA, Miyamoto S, Yoshinaga MY, Festuccia WT
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Mar;1868(3):159264
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Mar;1868(3):159264
Proteomics reveals defective peroxisomal fatty acid oxidation during the progression of acute kidney injury and repair.
Chen J, Zheng QY, Wang LM, Luo J, Chen KH, He YN
Heliyon 2023 Jul;9(7):e18134
Heliyon 2023 Jul;9(7):e18134
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Ding M, Zhou F, Li Y, Liu C, Gu Y, Wu J, Fan G, Li Y, Li X
Chinese herbal medicines 2023 Jul;15(3):421-429
Chinese herbal medicines 2023 Jul;15(3):421-429
Hepatic DKK1-driven steatosis is CD36 dependent.
Yang Z, Huang X, Zhang J, You K, Xiong Y, Fang J, Getachew A, Cheng Z, Yu X, Wang Y, Wu F, Wang N, Feng S, Lin X, Yang F, Chen Y, Wei H, Li YX
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Landowski M, Bhute VJ, Grindel S, Haugstad Z, Gyening YK, Tytanic M, Brush RS, Moyer LJ, Nelson DW, Davis CR, Yen CE, Ikeda S, Agbaga MP, Ikeda A
Communications biology 2023 Jan 4;6(1):8
Communications biology 2023 Jan 4;6(1):8
LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease.
Bai M, Wu M, Jiang M, He J, Deng X, Xu S, Fan J, Miao M, Wang T, Li Y, Yu X, Wang L, Zhang Y, Huang S, Yang L, Jia Z, Zhang A
EMBO molecular medicine 2023 Feb 8;15(2):e16581
EMBO molecular medicine 2023 Feb 8;15(2):e16581
A cottonseed oil-enriched diet improves liver and plasma lipid levels in a male mouse model of fatty liver.
Son Y, Shockey J, Dowd MK, Shieh JG, Cooper JA, Paton CM
American journal of physiology. Regulatory, integrative and comparative physiology 2023 Feb 1;324(2):R171-R182
American journal of physiology. Regulatory, integrative and comparative physiology 2023 Feb 1;324(2):R171-R182
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Yuan T, Xia Y, Pan S, Li B, Ye Z, Yan X, Hu W, Li L, Song B, Yu W, Li H, Rao T, Lin F, Zhou X, Cheng F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
MAPL loss dysregulates bile and liver metabolism in mice.
Goyon V, Besse-Patin A, Zunino R, Ignatenko O, Nguyen M, Coyaud É, Lee JM, Nguyen BN, Raught B, McBride HM
EMBO reports 2023 Dec 6;24(12):e57972
EMBO reports 2023 Dec 6;24(12):e57972
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Chen H, Ma Y, Qi X, Tian J, Ma Y, Niu T
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Li Y, Liu Y, Chen Z, Tang K, Yang L, Jiang Y, Wang J, Huang P, Wang J, Zheng P, Song H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Chen H, Qi X, Guan K, Wang R, Li Q, Ma Y
Journal of dairy science 2023 Apr;106(4):2271-2288
Journal of dairy science 2023 Apr;106(4):2271-2288
RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis.
Ding H, Yu JH, Ge G, Ma YY, Wang JC, Zhang J, Liu J
Journal of clinical and translational hepatology 2023 Apr 28;11(2):261-272
Journal of clinical and translational hepatology 2023 Apr 28;11(2):261-272
The Adaptive Characteristics of Cholesterol and Bile Acid Metabolism in Nile Tilapia Fed a High-Fat Diet.
Li RX, Qian YF, Zhou WH, Wang JX, Zhang YY, Luo Y, Qiao F, Chen LQ, Zhang ML, Du ZY
Aquaculture nutrition 2022;2022:8016616
Aquaculture nutrition 2022;2022:8016616
Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARα Signaling Pathway.
Huang P, Yang L, Liu Y, Jiang Y, Li Y, Chen Z, Song H, Zheng P
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1124901
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1124901
Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice.
Shimizu K, Nishimuta S, Fukumura Y, Michinaga S, Egusa Y, Hase T, Terada T, Sakurai F, Mizuguchi H, Tomita K, Nishinaka T
PloS one 2022;17(9):e0274297
PloS one 2022;17(9):e0274297
D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.
Hu M, Chen Y, Deng F, Chang B, Luo J, Dong L, Lu X, Zhang Y, Chen Z, Zhou J
Frontiers in immunology 2022;13:877650
Frontiers in immunology 2022;13:877650
ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma.
Zhao Z, Zhao Z, Wang J, Zhang H, Xi Z, Xia Q
Frontiers in oncology 2022;12:840287
Frontiers in oncology 2022;12:840287
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
Dong S, Li S, Wang X, Liang S, Zhang W, Li L, Xu Q, Shi B, Cheng Z, Zhang X, Zhong M, Zhang G, Hu S
Frontiers in oncology 2022;12:813852
Frontiers in oncology 2022;12:813852
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Dai W, Xiang W, Han L, Yuan Z, Wang R, Ma Y, Yang Y, Cai S, Xu Y, Mo S, Li Q, Cai G
Cancer communications (London, England) 2022 Sep;42(9):848-867
Cancer communications (London, England) 2022 Sep;42(9):848-867
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
Tong Y, Sun M, Chen L, Wang Y, Li Y, Li L, Zhang X, Cai Y, Qie J, Pang Y, Xu Z, Zhao J, Zhang X, Liu Y, Tian S, Qin Z, Feng J, Zhang F, Zhu J, Xu Y, Lou W, Ji Y, Zhao J, He F, Hou Y, Ding C
Journal of hematology & oncology 2022 Nov 25;15(1):168
Journal of hematology & oncology 2022 Nov 25;15(1):168
FGF21 Reduces Lipid Accumulation in Bovine Hepatocytes by Enhancing Lipid Oxidation and Reducing Lipogenesis via AMPK Signaling.
Kong Y, Zhao C, Tan P, Liu S, Huang Y, Zeng F, Ma P, Guo Y, Zhao B, Wang J
Animals : an open access journal from MDPI 2022 Apr 6;12(7)
Animals : an open access journal from MDPI 2022 Apr 6;12(7)
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Zhang G, Han J, Wang L, Yang X, Yan Z, Qu M, Zhou H, Bilal H, Wang F, Ge H, Yang X
iScience 2022 Apr 15;25(4):104085
iScience 2022 Apr 15;25(4):104085
Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect.
Klouwer FCC, Falkenberg KD, Ofman R, Koster J, van Gent D, Ferdinandusse S, Wanders RJA, Waterham HR
Frontiers in cell and developmental biology 2021;9:661298
Frontiers in cell and developmental biology 2021;9:661298
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
Mu Y, Maharjan Y, Kumar Dutta R, Wei X, Kim JH, Son J, Park C, Park R
PloS one 2021;16(2):e0245799
PloS one 2021;16(2):e0245799
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Guo W, Zhong W, Hao L, Dong H, Sun X, Yue R, Li T, Zhou Z
Cellular and molecular gastroenterology and hepatology 2021;12(5):1599-1615
Cellular and molecular gastroenterology and hepatology 2021;12(5):1599-1615
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087
Frontiers in pharmacology 2021;12:741087
The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells.
Zhang H, Shen Y, Kim IM, Weintraub NL, Tang Y
Frontiers in endocrinology 2021;12:642857
Frontiers in endocrinology 2021;12:642857
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Xu Y, Denning KL, Lu Y
Biochemical pharmacology 2021 Oct;192:114678
Biochemical pharmacology 2021 Oct;192:114678
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Ma C, Wang Z, Xia R, Wei L, Zhang C, Zhang J, Zhao L, Wu H, Kang L, Yang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity.
Xiong Y, Chen Y, Huang X, Yang Z, Zhang J, Yu X, Fang J, Tao J, You K, Cheng Z, Tan S, Xu Y, Yuan F, Liu Y, Zhuang Y, Yang F, Li Y
Life sciences 2021 Mar 1;268:119000
Life sciences 2021 Mar 1;268:119000
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Chen X, Xu Y, Denning KL, Grigore A, Lu Y
Free radical biology & medicine 2021 Jun;169:283-293
Free radical biology & medicine 2021 Jun;169:283-293
Elucidation of the mechanism of NEFA-induced PERK-eIF2α signaling pathway regulation of lipid metabolism in bovine hepatocytes.
Huang Y, Zhao C, Kong Y, Tan P, Liu S, Liu Y, Zeng F, Yuan Y, Zhao B, Wang J
The Journal of steroid biochemistry and molecular biology 2021 Jul;211:105893
The Journal of steroid biochemistry and molecular biology 2021 Jul;211:105893
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, Yuan C, Shi Y
Journal of cellular physiology 2021 Jan;236(1):625-640
Journal of cellular physiology 2021 Jan;236(1):625-640
CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα.
Zayed MA, Jin X, Yang C, Belaygorod L, Engel C, Desai K, Harroun N, Saffaf O, Patterson BW, Hsu FF, Semenkovich CF
Diabetes 2021 Feb;70(2):549-561
Diabetes 2021 Feb;70(2):549-561
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation.
Cholico GN, Fling RR, Zacharewski NA, Fader KA, Nault R, Zacharewski TR
Scientific reports 2021 Aug 3;11(1):15689
Scientific reports 2021 Aug 3;11(1):15689
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Han C, Jiang YH, Li W, Liu Y
Journal of ethnopharmacology 2021 Apr 6;269:113768
Journal of ethnopharmacology 2021 Apr 6;269:113768
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, Zhang J, Liu J
Nutrition & metabolism 2020;17:46
Nutrition & metabolism 2020;17:46
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Gao Y, Zhang S, Li J, Zhao J, Xiao Q, Zhu Y, Zhang J, Huang W
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
Shen S, Faouzi S, Souquere S, Roy S, Routier E, Libenciuc C, André F, Pierron G, Scoazec JY, Robert C
Cell reports 2020 Nov 24;33(8):108421
Cell reports 2020 Nov 24;33(8):108421
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression.
Xu L, Xia H, Ni D, Hu Y, Liu J, Qin Y, Zhou Q, Yi Q, Xie Y
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
Miyamoto T, Hosoba K, Itabashi T, Iwane AH, Akutsu SN, Ochiai H, Saito Y, Yamamoto T, Matsuura S
The EMBO journal 2020 Jun 17;39(12):e103499
The EMBO journal 2020 Jun 17;39(12):e103499
Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
He A, Chen X, Tan M, Chen Y, Lu D, Zhang X, Dean JM, Razani B, Lodhi IJ
Molecular cell 2020 Jul 2;79(1):30-42.e4
Molecular cell 2020 Jul 2;79(1):30-42.e4
Impact of discontinuation of fish oil after pioglitazone-fish oil combination therapy in diabetic KK mice.
Iizuka Y, Chiba K, Kim H, Hirako S, Wada M, Matsumoto A
The Journal of nutritional biochemistry 2020 Feb;76:108265
The Journal of nutritional biochemistry 2020 Feb;76:108265
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Luo Y, Xie C, Brocker CN, Fan J, Wu X, Feng L, Wang Q, Zhao J, Lu D, Tandon M, Cam M, Krausz KW, Liu W, Gonzalez FJ
Gastroenterology 2019 Sep;157(3):744-759.e4
Gastroenterology 2019 Sep;157(3):744-759.e4
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Zhang Y, Wang S, Zhao T, Yang L, Guo S, Shi Y, Zhang X, Zhou L, Ye L
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression.
Kumar S, Rani R, Karns R, Gandhi CR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3825-3840
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3825-3840
Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats.
Zhang YZ, Zhang ZM, Zhou LT, Zhu J, Zhang XH, Qi W, Ding S, Xu Q, Han X, Zhao YM, Song XY, Zhao TY, Ye L
Biomedical and environmental sciences : BES 2019 Jun;32(6):406-418
Biomedical and environmental sciences : BES 2019 Jun;32(6):406-418
Effect of selenium nanoparticles against abnormal fatty acid metabolism induced by hexavalent chromium in chicken's liver.
Luo M, Huang S, Zhang J, Zhang L, Mehmood K, Jiang J, Zhang N, Zhou D
Environmental science and pollution research international 2019 Jul;26(21):21828-21834
Environmental science and pollution research international 2019 Jul;26(21):21828-21834
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.
Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ
The Journal of clinical investigation 2019 Feb 1;129(2):694-711
The Journal of clinical investigation 2019 Feb 1;129(2):694-711
miR-222 targets ACOX1, promotes triglyceride accumulation in hepatocytes.
Wang JJ, Zhang YT, Tseng YJ, Zhang J
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Aug;18(4):360-365
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Aug;18(4):360-365
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2.
Lai YH, Liu H, Chiang WF, Chen TW, Chu LJ, Yu JS, Chen SJ, Chen HC, Tan BC
Theranostics 2018;8(2):486-504
Theranostics 2018;8(2):486-504
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D
EMBO reports 2018 May;19(5)
EMBO reports 2018 May;19(5)
A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase.
Ferdinandusse S, Denis S, van Roermund CWT, Preece MA, Koster J, Ebberink MS, Waterham HR, Wanders RJA
Biochimica et biophysica acta. Molecular basis of disease 2018 Mar;1864(3):952-958
Biochimica et biophysica acta. Molecular basis of disease 2018 Mar;1864(3):952-958
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2018 Jan 11;8(1):408
Scientific reports 2018 Jan 11;8(1):408
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
Lyu Z, Mao Z, Li Q, Xia Y, Liu Y, He Q, Wang Y, Zhao H, Lu Z, Zhou Q
EBioMedicine 2018 Dec;38:178-190
EBioMedicine 2018 Dec;38:178-190
PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation.
Eun SY, Lee JN, Nam IK, Liu ZQ, So HS, Choe SK, Park R
Experimental & molecular medicine 2018 Apr 6;50(4):1-12
Experimental & molecular medicine 2018 Apr 6;50(4):1-12
p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure.
Xiao Y, Wang J, Yan W, Zhou K, Cao Y, Cai W
Cell death & disease 2017 Oct 12;8(10):e3110
Cell death & disease 2017 Oct 12;8(10):e3110
SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p.
Sun LN, Zhi Z, Chen LY, Zhou Q, Li XM, Gan WJ, Chen S, Yang M, Liu Y, Shen T, Xu Y, Li JM
Cancer letters 2017 Nov 28;409:104-115
Cancer letters 2017 Nov 28;409:104-115
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2017 Aug 21;7(1):8976
Scientific reports 2017 Aug 21;7(1):8976
Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice.
Sun Q, Zhang W, Zhong W, Sun X, Zhou Z
Alcoholism, clinical and experimental research 2016 Oct;40(10):2076-2084
Alcoholism, clinical and experimental research 2016 Oct;40(10):2076-2084
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Niewiadomski J, Zhou JQ, Roman HB, Liu X, Hirschberger LL, Locasale JW, Stipanuk MH
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek LM, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, Leutz A, Sonenberg N, Wang ZQ, von Maltzahn J, Müller C, Calkhoven CF
EMBO reports 2015 Aug;16(8):1022-36
EMBO reports 2015 Aug;16(8):1022-36
Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration.
Wang Y, Kou Y, Wang X, Cederbaum A, Wang R
PloS one 2014;9(3):e92504
PloS one 2014;9(3):e92504
Dietary nicotinic acid supplementation ameliorates chronic alcohol-induced fatty liver in rats.
Li Q, Xie G, Zhang W, Zhong W, Sun X, Tan X, Sun X, Jia W, Zhou Z
Alcoholism, clinical and experimental research 2014 Jul;38(7):1982-92
Alcoholism, clinical and experimental research 2014 Jul;38(7):1982-92
Expressional studies of the aldehyde oxidase (AOX1) gene during myogenic differentiation in C2C12 cells.
Kamli MR, Kim J, Pokharel S, Jan AT, Lee EJ, Choi I
Biochemical and biophysical research communications 2014 Aug 8;450(4):1291-6
Biochemical and biophysical research communications 2014 Aug 8;450(4):1291-6
Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice.
Sun X, Tang Y, Tan X, Li Q, Zhong W, Sun X, Jia W, McClain CJ, Zhou Z
American journal of physiology. Gastrointestinal and liver physiology 2012 Mar 1;302(5):G548-57
American journal of physiology. Gastrointestinal and liver physiology 2012 Mar 1;302(5):G548-57
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation.
Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, Russell AP, Gerber AN, Bai X, Yan Z, Nosek TM, Brotto M, Hoppel CL, Jain MK
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 24;109(17):6739-44
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 24;109(17):6739-44
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Kassmann CM, Quintes S, Rietdorf J, Möbius W, Sereda MW, Nientiedt T, Saher G, Baes M, Nave KA
FEBS letters 2011 Jul 21;585(14):2205-11
FEBS letters 2011 Jul 21;585(14):2205-11
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F
PloS one 2009 Oct 28;4(10):e7641
PloS one 2009 Oct 28;4(10):e7641
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10957-1-AP(AOX antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 10957-1-AP(AOX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACOX1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACOX1. This antibody recognizes human,mouse,rat antigen. The ACOX1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
