DCABH-8912

antibody from Creative Diagnostics

Targeting: CNN1 Sm-Calp, SMCC

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DCABH-8912

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-8912, RRID:AB_2481960

Product name

Rabbit Anti-Human Calponin 1 monoclonal antibody, clone FQ809Z

Antibody type

Monoclonal

Description

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

FQ809Z

Storage

4°C