orb2638312

antibody from Biorbyt

Targeting: CNN1 Sm-Calp, SMCC

Western blot

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

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Validation data

Product number: orb2638312 - Provider product page
Provider: Biorbyt
Product name: Calponin 1 Antibody
Antibody type: Monoclonal
Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kDa form and a 29kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this mAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Reactivity: Human, Rat
Host: Mouse
Conjugate: Unconjugated
Antibody clone number: CALP
Vial size: 100 ug
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

CNN1 protein structure - orb2638312 shown in red.