Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [4]
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Validation data
Reference
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- Product number
- 21404-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21404-1-AP, RRID:AB_10732819
- Product name
- SMMHC antibody
- Antibody type
- Polyclonal
- Description
- SMMHC antibody (Cat. #21404-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways.
MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.
TWIST1 induces phenotypic switching of vascular smooth muscle cells by downregulating p68 and microRNA-143/145.
Modulation of Vascular Smooth Muscle Cell Phenotype by High Mobility Group AT-Hook 1.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Neonatal Streptococcus Pneumoniae pneumonia induces airway SMMHC expression through HMGB1/TLR4/ERK.
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis.
Vascular Adhesion Protein-1 Determines the Cellular Properties of Endometrial Pericytes.
Bioinformatics Analysis Reveals MicroRNA-193a-3p Regulates ACTG2 to Control Phenotype Switch in Human Vascular Smooth Muscle Cells.
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2.
Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction.
Autophagy is involved in the differentiation of epicardial progenitor cells into vascular smooth muscle cells in mice.
CTRP13 attenuates vascular calcification by regulating Runx2.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
CD137-CD137L interaction modulates neointima formation and the phenotype transformation of vascular smooth muscle cells via NFATc1 signaling.
The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling.
Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE-/- mice.
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
Regulated lysosomal exocytosis mediates cancer progression.
Wang M, Luo P, Shi W, Guo J, Huo S, Yan D, Peng L, Zhang C, Lv J, Lin L, Li S
Oxidative medicine and cellular longevity 2021;2021:6621232
Oxidative medicine and cellular longevity 2021;2021:6621232
MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.
Cao Y, Cao Z, Wang W, Jie X, Li L
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
TWIST1 induces phenotypic switching of vascular smooth muscle cells by downregulating p68 and microRNA-143/145.
Zhang J, Guo JR, Wu XL, Wang X, Zhu ZM, Wang Y, Gu X, Fan Y
FEBS open bio 2021 Mar;11(3):932-943
FEBS open bio 2021 Mar;11(3):932-943
Modulation of Vascular Smooth Muscle Cell Phenotype by High Mobility Group AT-Hook 1.
Jung Y, Lee HS, Ha JM, Jin SY, Kum HJ, Vafaeinik F, Ha HK, Song SH, Kim CD, Bae SS
Journal of lipid and atherosclerosis 2021 Jan;10(1):99-110
Journal of lipid and atherosclerosis 2021 Jan;10(1):99-110
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Neonatal Streptococcus Pneumoniae pneumonia induces airway SMMHC expression through HMGB1/TLR4/ERK.
Li Y, Guo Z, Zhang G, Tian X, Li Q, Luo Z
Immunology letters 2021 Dec;240:149-158
Immunology letters 2021 Dec;240:149-158
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis.
Childs BG, Zhang C, Shuja F, Sturmlechner I, Trewartha S, Fierro Velasco R, Baker D, Li H, van Deursen JM
Nature aging 2021 Aug;1(8):698-714
Nature aging 2021 Aug;1(8):698-714
Vascular Adhesion Protein-1 Determines the Cellular Properties of Endometrial Pericytes.
Gharanei S, Fishwick K, Peter Durairaj R, Jin T, Siamantouras E, Liu KK, Straube A, Lucas ES, Weston CJ, Rantakari P, Salmi M, Jalkanen S, Brosens JJ, Tan BK
Frontiers in cell and developmental biology 2020;8:621016
Frontiers in cell and developmental biology 2020;8:621016
Bioinformatics Analysis Reveals MicroRNA-193a-3p Regulates ACTG2 to Control Phenotype Switch in Human Vascular Smooth Muscle Cells.
Wang W, Wang Y, Piao H, Li B, Zhu Z, Li D, Wang T, Liu K
Frontiers in genetics 2020;11:572707
Frontiers in genetics 2020;11:572707
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811
Theranostics 2020;10(17):7787-7811
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, Chen J
International journal of molecular medicine 2019 Sep;44(3):871-884
International journal of molecular medicine 2019 Sep;44(3):871-884
Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.
Du H, Zhao Q, Zang H, Chang C, Li X
Life sciences 2019 Nov 15;237:116943
Life sciences 2019 Nov 15;237:116943
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2.
Wang C, Xu W, An J, Liang M, Li Y, Zhang F, Tong Q, Huang K
Nature communications 2019 Mar 13;10(1):1203
Nature communications 2019 Mar 13;10(1):1203
Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction.
Iguchi N, Dönmez Mİ, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG
American journal of physiology. Renal physiology 2019 Jul 1;317(1):F197-F206
American journal of physiology. Renal physiology 2019 Jul 1;317(1):F197-F206
Autophagy is involved in the differentiation of epicardial progenitor cells into vascular smooth muscle cells in mice.
Liu Y, Liu B, Li Y, Li Y, Du J, Deng S, Jing X, She Q
Experimental cell research 2019 Feb 15;375(2):60-71
Experimental cell research 2019 Feb 15;375(2):60-71
CTRP13 attenuates vascular calcification by regulating Runx2.
Li Y, Wang W, Chao Y, Zhang F, Wang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9627-9637
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9627-9637
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Zhang JR, Lu QB, Feng WB, Wang HP, Tang ZH, Cheng H, Du Q, Wang YB, Li KX, Sun HJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
CD137-CD137L interaction modulates neointima formation and the phenotype transformation of vascular smooth muscle cells via NFATc1 signaling.
Zhong W, Li B, Yang P, Chen R, Wang C, Wang Z, Shao C, Yuan W, Yan J
Molecular and cellular biochemistry 2018 Feb;439(1-2):65-74
Molecular and cellular biochemistry 2018 Feb;439(1-2):65-74
The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling.
Jourd'heuil FL, Xu H, Reilly T, McKellar K, El Alaoui C, Steppich J, Liu YF, Zhao W, Ginnan R, Conti D, Lopez-Soler R, Asif A, Keller RK, Schwarz JJ, Thanh Thuy LT, Kawada N, Long X, Singer HA, Jourd'heuil D
Arteriosclerosis, thrombosis, and vascular biology 2017 Oct;37(10):1944-1955
Arteriosclerosis, thrombosis, and vascular biology 2017 Oct;37(10):1944-1955
Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE-/- mice.
Ganguly R, Sahu S, Ohanyan V, Haney R, Chavez RJ, Shah S, Yalamanchili S, Raman P
Scientific reports 2017 Mar 27;7:45279
Scientific reports 2017 Mar 27;7:45279
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
Yao Y, Hu Z, Ye J, Hu C, Song Q, Da X, Yu Y, Li H, Xu C, Chen Q, Wang QK
Journal of the American Heart Association 2017 Jun 25;6(6)
Journal of the American Heart Association 2017 Jun 25;6(6)
Regulated lysosomal exocytosis mediates cancer progression.
Machado E, White-Gilbertson S, van de Vlekkert D, Janke L, Moshiach S, Campos Y, Finkelstein D, Gomero E, Mosca R, Qiu X, Morton CL, Annunziata I, d'Azzo A
Science advances 2015 Dec;1(11):e1500603
Science advances 2015 Dec;1(11):e1500603
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse uterus tissue were subjected to SDS PAGE followed by western blot with 21404-1-AP(MYH11 antibody) at dilution of 1:3000
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MYH11 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MYH11. This antibody recognizes human, mouse antigen. The MYH11 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 21404-1-AP(MYH11 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 21404-1-AP(MYH11 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 21404-1-AP(MYH11 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue