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- Antibody Data
- Antigen structure
- References [190]
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- Product number
- 12217-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12217-1-AP, RRID:AB_2087497
- Product name
- Gamma Cystathionase antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Gamma Cystathionase antibody (Cat. #12217-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cystathionine γ-lyase-derived H(2)S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase.
Targeting Ferroptosis-Elicited Inflammation Suppresses Hepatocellular Carcinoma Metastasis and Enhances Sorafenib Efficacy.
The Effect of Targeted Hyperoxemia on Brain Immunohistochemistry after Long-Term, Resuscitated Porcine Acute Subdural Hematoma and Hemorrhagic Shock.
Loss of cardiac mitochondrial complex I persulfidation impairs NAD(+) homeostasis in aging.
Identifying CTH and MAP1LC3B as ferroptosis biomarkers for prognostic indication in gastric cancer decoding.
Breast cancer cells have an increased ferroptosis risk induced by system x(c)(-) blockade after deliberately downregulating CYTL1 to mediate malignancy.
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Hydrogen sulfide inhibits the rupture of fetal membranes throngh anti-aging pathways.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis.
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma.
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Hypoxia increases persulfide and polysulfide formation by AMP kinase dependent cystathionine gamma lyase phosphorylation.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Choline induced cardiac dysfunction by inhibiting the production of endogenous hydrogen sulfide in spontaneously hypertensive rats.
Ethanol inhibition of undifferentiated rat neural progenitor cell replication can be prevented by chlorogenic acid via the NFATc4/CSE signaling pathway.
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H(2)S lead to H(2)S deficiency in calcific aortic valve disease.
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis.
Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer.
Hydrogen sulfide alleviates uremic cardiomyopathy by regulating PI3K/PKB/mTOR-mediated overactive autophagy in 5/6 nephrectomy mice.
Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT.
Perinatal Garlic Oil Supplementation Averts Rat Offspring Hypertension Programmed by Maternal Chronic Kidney Disease.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Hydrogen Sulfide Metabolizing Enzymes in the Intestinal Mucosa in Pediatric and Adult Inflammatory Bowel Disease.
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling.
The Vasoactive Effect of Perivascular Adipose Tissue and Hydrogen Sulfide in Thoracic Aortas of Normotensive and Spontaneously Hypertensive Rats.
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Vasorelaxant Activity of AP39, a Mitochondria-Targeted H(2)S Donor, on Mouse Mesenteric Artery Rings In Vitro.
Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver.
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Protective Effects of Allicin on Acute Myocardial Infarction in Rats via Hydrogen Sulfide-mediated Regulation of Coronary Arterial Vasomotor Function and Myocardial Calcium Transport.
Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
The Gasotransmitter Hydrogen Sulfide (H(2)S) Prevents Pathologic Calcification (PC) in Cartilage.
SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sulfide catabolism ameliorates hypoxic brain injury.
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage.
Abnormal nitration and S-sulfhydration modification of Sp1-CSE-H(2)S pathway trap the progress of hyperhomocysteinemia into a vicious cycle.
Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure.
Microbiota transplants from feces or gut content attenuated portal hypertension and portosystemic collaterals in cirrhotic rats.
Intracellular H(2)S production is an autophagy-dependent adaptive response to DNA damage.
Maternal Separation Induces Long-Term Alterations in the Cardiac Oxytocin Receptor and Cystathionine γ-Lyase Expression in Mice.
Cyanidin-3-O-Glucoside Improves Colonic Motility During Severe Acute Pancreatitis by Inhibiting the H(2)S-Regulated AMPK/mTOR Pathway.
Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner.
Honokiol ameliorates angiotensin II-induced hypertension and endothelial dysfunction by inhibiting HDAC6-mediated cystathionine γ-lyase degradation.
Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells.
Maternal N-Acetylcysteine Therapy Prevents Hypertension in Spontaneously Hypertensive Rat Offspring: Implications of Hydrogen Sulfide-Generating Pathway and Gut Microbiota.
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
Inhibition of endogenous hydrogen sulfide biosynthesis enhances the anti-cancer effect of 3,3'-diindolylmethane in human gastric cancer cells.
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2.
Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis.
Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation.
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.
Endometrial Axin2(+) Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation.
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Vasorelaxation elicited by endogenous and exogenous hydrogen sulfide in mouse mesenteric arteries.
Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia.
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Hydrogen sulfide inhibited L-type calcium channels (CaV1.2) via up-regulation of the channel sulfhydration in vascular smooth muscle cells.
17β-Estradiol nongenomically induces vascular endothelial H(2)S release by promoting phosphorylation of cystathionine γ-lyase.
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension.
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Hydrogen sulfide stimulates activation of hepatic stellate cells through increased cellular bio-energetics.
Hydrogen sulfide regulation of renal and mesenteric blood flow.
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine γ-lyase-dependent hydrogen sulfide synthesis.
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions.
Histone deacetylase 6 inhibitor tubastatin A attenuates angiotensin II-induced hypertension by preventing cystathionine γ-lyase protein degradation.
Exogenous H(2)S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD(+)-SIRT3 pathway in cardiac tissues of db/db mice.
Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis.
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress.
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
A selective and sensitive method for quantification of endogenous polysulfide production in biological samples.
Intermittent hypoxia exacerbates increased blood pressure in rats with chronic kidney disease.
Alpha-lipoic acid regulates the autophagy of vascular smooth muscle cells in diabetes by elevating hydrogen sulfide level.
Role for Cystathionine γ Lyase (CSE) in an Ethanol (E)-Induced Lesion in Fetal Brain GSH Homeostasis.
Drug resistance induces the upregulation of H(2)S-producing enzymes in HCT116 colon cancer cells.
Endogenous H(2)S sensitizes PAR4-induced bladder pain.
Early Supplementation of d-Cysteine or l-Cysteine Prevents Hypertension and Kidney Damage in Spontaneously Hypertensive Rats Exposed to High-Salt Intake.
Reduced adipose tissue H(2)S in obesity.
Diurnal Fluctuations in Plasma Hydrogen Sulfide of the Mice.
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Hydrogen sulfide improves diabetic wound healing in ob/ob mice via attenuating inflammation.
Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway.
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide.
Augmentation of cGMP/PKG pathway and colonic motility by hydrogen sulfide.
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency.
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Production of endogenous hydrogen sulfide in human gingival tissue.
Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection.
Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock.
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
Reciprocal regulation of eNOS, H(2)S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin.
Role of thiosulfate in hydrogen sulfide-dependent redox signaling in endothelial cells.
mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression.
Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.
Protective effects of hydrogen sulfide against angiotensin II-induced endoplasmic reticulum stress in HUVECs.
NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to intermittent hypoxia.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway.
Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock.
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N(G)-Nitro-L-arginine-methyl ester (L-NAME)-induced fetal programming of hypertension in adult male offspring.
The novel H(2) S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.
Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway.
Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction.
Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.
Radiation Exposure Promotes Hepatocarcinoma Cell Invasion through Epithelial Mesenchymal Transition Mediated by H2S/CSE Pathway.
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting the expression of peroxiredoxin III in H9c2 cells.
MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery.
Maternal N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and prevents programmed hypertension in male offspring exposed to prenatal dexamethasone and postnatal high-fat diet.
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.
Effects of hydrogen sulfide on high glucose-induced glomerular podocyte injury in mice.
Neuroprotective effects of hydrogen sulfide in Parkinson's disease animal models: methods and protocols.
Mitochondria-targeted hydrogen sulfide donor AP39 improves neurological outcomes after cardiac arrest in mice.
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells.
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes.
Role of cystathionine beta synthase in lipid metabolism in ovarian cancer.
Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S.
Evidence for a functional vasodilatatory role for hydrogen sulphide in the human cutaneous microvasculature.
Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells.
Hydrogen sulfide is essential for Schwann cell responses to peripheral nerve injury.
Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.
Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia-inducible factor-1α.
Hydrogen sulfide-induced enhancement of gastric fundus smooth muscle tone is mediated by voltage-dependent potassium and calcium channels in mice.
The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide.
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.
S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair.
Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons.
Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism.
Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance.
H2 S inhibits the activation of hepatic stellate cells and downregulates the expression of urotensin II.
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).
Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells.
Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress.
The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma.
Suppression of endogenous hydrogen sulfide contributes to the radiation-induced bystander effects on hypoxic HepG2 cells.
Is cystathionine gamma-lyase protein expressed in the heart?
Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism.
Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress.
Hydrogen sulfide contributes to hypoxia-induced radioresistance on hepatoma cells.
Hydrogen Sulfide in the RVLM and PVN has No Effect on Cardiovascular Regulation.
Cadmium induced radioadaptive response via an ATM-independent H(2)S/cystathionine γ-lyase modulation.
Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta.
The dual role of the cystathionine gamma-lyase/hydrogen sulfide pathway in CVB3-induced myocarditis in mice.
Hu YT, Liu ZW, Zhang TH, Ma YE, He L, Zhang J, Zhou YY, Vidal-Puig A, Pan DJ, Wu F
Acta pharmacologica Sinica 2024 Nov;45(11):2366-2379
Acta pharmacologica Sinica 2024 Nov;45(11):2366-2379
Targeting Ferroptosis-Elicited Inflammation Suppresses Hepatocellular Carcinoma Metastasis and Enhances Sorafenib Efficacy.
Mu M, Huang CX, Qu C, Li PL, Wu XN, Yao W, Shen C, Huang R, Wan CC, Jian ZW, Zheng L, Wu RQ, Lao XM, Kuang DM
Cancer research 2024 Mar 15;84(6):841-854
Cancer research 2024 Mar 15;84(6):841-854
The Effect of Targeted Hyperoxemia on Brain Immunohistochemistry after Long-Term, Resuscitated Porcine Acute Subdural Hematoma and Hemorrhagic Shock.
Münz F, Datzmann T, Hoffmann A, Gröger M, Mathieu R, Mayer S, Zink F, Gässler H, Wolfschmitt EM, Hogg M, Calzia E, Asfar P, Radermacher P, Kapapa T, Merz T
International journal of molecular sciences 2024 Jun 14;25(12)
International journal of molecular sciences 2024 Jun 14;25(12)
Loss of cardiac mitochondrial complex I persulfidation impairs NAD(+) homeostasis in aging.
Drekolia MK, Karantanou C, Wittig I, Li Y, Fuhrmann DC, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli SI
Redox biology 2024 Feb;69:103014
Redox biology 2024 Feb;69:103014
Identifying CTH and MAP1LC3B as ferroptosis biomarkers for prognostic indication in gastric cancer decoding.
Qu H, Liang Y, Guo Q, Lu L, Yang Y, Xu W, Zhang Y, Qin Y
Scientific reports 2024 Feb 22;14(1):4352
Scientific reports 2024 Feb 22;14(1):4352
Breast cancer cells have an increased ferroptosis risk induced by system x(c)(-) blockade after deliberately downregulating CYTL1 to mediate malignancy.
Xue W, Yu Y, Yao Y, Zhou L, Huang Y, Wang Y, Chen Z, Wang L, Li X, Wang X, Du R, Shen Y, Xu Q
Redox biology 2024 Apr;70:103034
Redox biology 2024 Apr;70:103034
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
Li Q, Kang J, Liu N, Huang J, Zhang X, Pang K, Zhang S, Wang M, Zhao Y, Dong S, Li H, Zhao D, Lu F, Zhang W
Free radical biology & medicine 2024 Apr;216:118-138
Free radical biology & medicine 2024 Apr;216:118-138
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
Li J, Feng C, Pang X, Li X, Dou X, Jiang E, Shang Z
Discover oncology 2024 Apr 8;15(1):109
Discover oncology 2024 Apr 8;15(1):109
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Dilxat T, Shi Q, Chen X, Liu X
Aging 2024 Apr 12;16(7):6521-6536
Aging 2024 Apr 12;16(7):6521-6536
PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.
Yamamoto T, Hayashida T, Masugi Y, Oshikawa K, Hayakawa N, Itoh M, Nishime C, Suzuki M, Nagayama A, Kawai Y, Hishiki T, Matsuura T, Naito Y, Kubo A, Yamamoto A, Yoshioka Y, Kurahori T, Nagasaka M, Takizawa M, Takano N, Kawakami K, Sakamoto M, Wakui M, Yamamoto T, Kitagawa Y, Kabe Y, Horisawa K, Suzuki A, Matsumoto M, Suematsu M
Cancer research 2024 Apr 1;84(7):1065-1083
Cancer research 2024 Apr 1;84(7):1065-1083
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Katsouda A, Markou M, Zampas P, Varela A, Davos CH, Vellecco V, Cirino G, Bucci M, Papapetropoulos A
Frontiers in pharmacology 2023;14:1090654
Frontiers in pharmacology 2023;14:1090654
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Hydrogen sulfide inhibits the rupture of fetal membranes throngh anti-aging pathways.
Wang J, Xu J, Chao B, Liu H, Xie L, Qi H, Luo X
Placenta 2023 Nov;143:22-33
Placenta 2023 Nov;143:22-33
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Yoon SJ, Combs JA, Falzone A, Prieto-Farigua N, Caldwell S, Ackerman HD, Flores ER, DeNicola GM
Cancer research 2023 May 2;83(9):1426-1442
Cancer research 2023 May 2;83(9):1426-1442
B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis.
Du X, Ma X, Tan Y, Shao F, Li C, Zhao Y, Miao Y, Han L, Dang G, Song Y, Yang D, Deng Z, Wang Y, Jiang C, Kong W, Feng J, Wang X
Signal transduction and targeted therapy 2023 Mar 13;8(1):103
Signal transduction and targeted therapy 2023 Mar 13;8(1):103
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Li H, Wei Y, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Hao J
Acta cardiologica 2023 Jul;78(5):594-606
Acta cardiologica 2023 Jul;78(5):594-606
Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma.
Idei U, Ohta T, Yamatani H, Seino M, Nagase S
International journal of molecular sciences 2023 Jul 22;24(14)
International journal of molecular sciences 2023 Jul 22;24(14)
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Bell HN, Huber AK, Singhal R, Korimerla N, Rebernick RJ, Kumar R, El-Derany MO, Sajjakulnukit P, Das NK, Kerk SA, Solanki S, James JG, Kim D, Zhang L, Chen B, Mehra R, Frankel TL, Győrffy B, Fearon ER, Pasca di Magliano M, Gonzalez FJ, Banerjee R, Wahl DR, Lyssiotis CA, Green M, Shah YM
Cell metabolism 2023 Jan 3;35(1):134-149.e6
Cell metabolism 2023 Jan 3;35(1):134-149.e6
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Hypoxia increases persulfide and polysulfide formation by AMP kinase dependent cystathionine gamma lyase phosphorylation.
Alam S, Pardue S, Shen X, Glawe JD, Yagi T, Bhuiyan MAN, Patel RP, Dominic PS, Virk CS, Bhuiyan MS, Orr AW, Petit C, Kolluru GK, Kevil CG
Redox biology 2023 Dec;68:102949
Redox biology 2023 Dec;68:102949
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Choline induced cardiac dysfunction by inhibiting the production of endogenous hydrogen sulfide in spontaneously hypertensive rats.
Zhang W, Zhang Y, Xia Y, Feng G, Wang Y, Wei C, Tang A, Song K, Qiu R, Wu Y, Jin S
Physiological research 2023 Dec 31;72(6):719-730
Physiological research 2023 Dec 31;72(6):719-730
Ethanol inhibition of undifferentiated rat neural progenitor cell replication can be prevented by chlorogenic acid via the NFATc4/CSE signaling pathway.
Shanmugam S, Patel D, Rodriguez AL, Walchale A, Liu X, Bergeson SE, Mahimainathan L, Narasimhan M, Henderson GI
Alcohol, clinical & experimental research 2023 Aug;47(8):1530-1543
Alcohol, clinical & experimental research 2023 Aug;47(8):1530-1543
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Cui X, Yao M, Feng Y, Li C, Li Y, Guo D, He S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H(2)S lead to H(2)S deficiency in calcific aortic valve disease.
Combi Z, Potor L, Nagy P, Sikura KÉ, Ditrói T, Jurányi EP, Galambos K, Szerafin T, Gergely P, Whiteman M, Torregrossa R, Ding Y, Beke L, Hendrik Z, Méhes G, Balla G, Balla J
Redox biology 2023 Apr;60:102629
Redox biology 2023 Apr;60:102629
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Peng S, Wang M, Zhang S, Liu N, Li Q, Kang J, Chen L, Li M, Pang K, Huang J, Lu F, Zhao D, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114200
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114200
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Cornwell A, Ziółkowski H, Badiei A
Biomolecules 2023 Apr 29;13(5)
Biomolecules 2023 Apr 29;13(5)
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Liang Z, Miao Y, Teng X, Xiao L, Guo Q, Xue H, Tian D, Jin S, Wu Y
Frontiers in molecular biosciences 2022;9:947778
Frontiers in molecular biosciences 2022;9:947778
Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis.
Ye X, Li Y, Lv B, Qiu B, Zhang S, Peng H, Kong W, Tang C, Huang Y, Du J, Jin H
Oxidative medicine and cellular longevity 2022;2022:6153772
Oxidative medicine and cellular longevity 2022;2022:6153772
Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer.
Sendo K, Seino M, Ohta T, Nagase S
Oncotarget 2022;13:224-236
Oncotarget 2022;13:224-236
Hydrogen sulfide alleviates uremic cardiomyopathy by regulating PI3K/PKB/mTOR-mediated overactive autophagy in 5/6 nephrectomy mice.
Feng J, Li H, Wang S
Frontiers in pharmacology 2022;13:1027597
Frontiers in pharmacology 2022;13:1027597
Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
Thanki KK, Johnson P, Higgins EJ, Maskey M, Phillips C, Dash S, Almenas FA, Govar AA, Tian B, Villéger R, Beswick E, Wang R, Szabo C, Chao C, Pinchuk IV, Hellmich MR, Módis K
Redox biology 2022 Sep;55:102417
Redox biology 2022 Sep;55:102417
MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT.
Zhang J, Cen L, Zhang X, Tang C, Chen Y, Zhang Y, Yu M, Lu C, Li M, Li S, Lin B, Zhang T, Song X, Yu C, Wu H, Shen Z
Redox biology 2022 Oct;56:102469
Redox biology 2022 Oct;56:102469
Perinatal Garlic Oil Supplementation Averts Rat Offspring Hypertension Programmed by Maternal Chronic Kidney Disease.
Tain YL, Hou CY, Chang-Chien GP, Lin S, Hsu CN
Nutrients 2022 Nov 2;14(21)
Nutrients 2022 Nov 2;14(21)
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
Hydrogen Sulfide Metabolizing Enzymes in the Intestinal Mucosa in Pediatric and Adult Inflammatory Bowel Disease.
Stummer N, Weghuber D, Feichtinger RG, Huber S, Mayr JA, Kofler B, Neureiter D, Klieser E, Hochmann S, Lauth W, Schneider AM
Antioxidants (Basel, Switzerland) 2022 Nov 12;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 12;11(11)
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
Zhou X, Liu J, Zheng Y, Zhang Z, Wu Y, Yang W, Liu J, Huang Y, Yi Y, Zhao Z, Xiao H, Mo X, Wang J
Cell reports 2022 May 3;39(5):110750
Cell reports 2022 May 3;39(5):110750
Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling.
Fiore A, Zeitler L, Russier M, Groß A, Hiller MK, Parker JL, Stier L, Köcher T, Newstead S, Murray PJ
Molecular cell 2022 Mar 3;82(5):920-932.e7
Molecular cell 2022 Mar 3;82(5):920-932.e7
The Vasoactive Effect of Perivascular Adipose Tissue and Hydrogen Sulfide in Thoracic Aortas of Normotensive and Spontaneously Hypertensive Rats.
Golas S, Berenyiova A, Majzunova M, Drobna M, Tuorkey MJ, Cacanyiova S
Biomolecules 2022 Mar 16;12(3)
Biomolecules 2022 Mar 16;12(3)
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Xi Y, Wen X, Zhang Y, Jiao L, Bai S, Shi S, Chang G, Wu R, Sun F, Hao J, Li H
Aging and disease 2022 Jun;13(3):910-926
Aging and disease 2022 Jun;13(3):910-926
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
Li H, Wu R, Xi Y, Li H, Chang G, Sun F, Wei C, Jiao L, Wen X, Zhang G, Zaid A, Hao J
Cell biology international 2022 Jul;46(7):1098-1108
Cell biology international 2022 Jul;46(7):1098-1108
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity.
Katsouda A, Valakos D, Dionellis VS, Bibli SI, Akoumianakis I, Karaliota S, Zuhra K, Fleming I, Nagahara N, Havaki S, Gorgoulis VG, Thanos D, Antoniades C, Szabo C, Papapetropoulos A
The Journal of experimental medicine 2022 Jul 4;219(7)
The Journal of experimental medicine 2022 Jul 4;219(7)
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Wen X, Xi Y, Zhang Y, Jiao L, Shi S, Bai S, Sun F, Chang G, Wu R, Hao J, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease.
Hsu CN, Hou CY, Chang-Chien GP, Lin S, Yang HW, Tain YL
Antioxidants (Basel, Switzerland) 2022 Jan 11;11(1)
Antioxidants (Basel, Switzerland) 2022 Jan 11;11(1)
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Vasorelaxant Activity of AP39, a Mitochondria-Targeted H(2)S Donor, on Mouse Mesenteric Artery Rings In Vitro.
da Costa Marques LA, Teixeira SA, de Jesus FN, Wood ME, Torregrossa R, Whiteman M, Costa SKP, Muscará MN
Biomolecules 2022 Feb 9;12(2)
Biomolecules 2022 Feb 9;12(2)
Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver.
Yang B, Yin C, Zhang Y, Xing G, Wang S, Li F, Aschner M, Lu R
Toxicology research 2022 Apr;11(2):374-384
Toxicology research 2022 Apr;11(2):374-384
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Xu H, Wei K, Tu J, Chen Y, He Y, Ding Y, Xu H, Bao X, Xie H, Fang H, Wang H
Frontiers in cell and developmental biology 2021;9:741046
Frontiers in cell and developmental biology 2021;9:741046
Protective Effects of Allicin on Acute Myocardial Infarction in Rats via Hydrogen Sulfide-mediated Regulation of Coronary Arterial Vasomotor Function and Myocardial Calcium Transport.
Cui T, Liu W, Yu C, Ren J, Li Y, Shi X, Li Q, Zhang J
Frontiers in pharmacology 2021;12:752244
Frontiers in pharmacology 2021;12:752244
Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress.
Chen YH, Teng X, Hu ZJ, Tian DY, Jin S, Wu YM
Frontiers in physiology 2021;12:653601
Frontiers in physiology 2021;12:653601
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
The Gasotransmitter Hydrogen Sulfide (H(2)S) Prevents Pathologic Calcification (PC) in Cartilage.
Nasi S, Ehirchiou D, Bertrand J, Castelblanco M, Mitchell J, Ishii I, So A, Busso N
Antioxidants (Basel, Switzerland) 2021 Sep 8;10(9)
Antioxidants (Basel, Switzerland) 2021 Sep 8;10(9)
SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice.
Nguyen TTP, Kim DY, Lee YG, Lee YS, Truong XT, Lee JH, Song DK, Kwon TK, Park SH, Jung CH, Moon C, Osborne TF, Im SS, Jeon TI
Molecular cell 2021 Sep 16;81(18):3820-3832.e7
Molecular cell 2021 Sep 16;81(18):3820-3832.e7
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Sulfide catabolism ameliorates hypoxic brain injury.
Marutani E, Morita M, Hirai S, Kai S, Grange RMH, Miyazaki Y, Nagashima F, Traeger L, Magliocca A, Ida T, Matsunaga T, Flicker DR, Corman B, Mori N, Yamazaki Y, Batten A, Li R, Tanaka T, Ikeda T, Nakagawa A, Atochin DN, Ihara H, Olenchock BA, Shen X, Nishida M, Hanaoka K, Kevil CG, Xian M, Bloch DB, Akaike T, Hindle AG, Motohashi H, Ichinose F
Nature communications 2021 May 25;12(1):3108
Nature communications 2021 May 25;12(1):3108
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
Villa E, Sahu U, O'Hara BP, Ali ES, Helmin KA, Asara JM, Gao P, Singer BD, Ben-Sahra I
Molecular cell 2021 May 20;81(10):2076-2093.e9
Molecular cell 2021 May 20;81(10):2076-2093.e9
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Lai X, Wang M, Zhu Y, Feng X, Liang H, Wu J, Nie L, Li L, Shao L
Journal of hazardous materials 2021 May 15;410:124566
Journal of hazardous materials 2021 May 15;410:124566
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage.
Trautwein B, Merz T, Denoix N, Szabo C, Calzia E, Radermacher P, McCook O
Antioxidants (Basel, Switzerland) 2021 Feb 3;10(2)
Antioxidants (Basel, Switzerland) 2021 Feb 3;10(2)
Abnormal nitration and S-sulfhydration modification of Sp1-CSE-H(2)S pathway trap the progress of hyperhomocysteinemia into a vicious cycle.
Luo C, Ji D, Li Y, Cao Y, Zhang S, Yan W, Xue K, Chai J, Wu Y, Liu H, Wang W
Free radical biology & medicine 2021 Feb 20;164:20-33
Free radical biology & medicine 2021 Feb 20;164:20-33
Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure.
Barrera A, Morales-Loredo H, Garcia JM, Fregoso G, Pace CE, Mendiola PJ, Naik JS, Gonzalez Bosc LV, Kanagy NL
American journal of physiology. Heart and circulatory physiology 2021 Feb 1;320(2):H511-H519
American journal of physiology. Heart and circulatory physiology 2021 Feb 1;320(2):H511-H519
Microbiota transplants from feces or gut content attenuated portal hypertension and portosystemic collaterals in cirrhotic rats.
Huang HC, Tsai MH, Chang CC, Pun CK, Huang YH, Hou MC, Lee FY, Hsu SJ
Clinical science (London, England : 1979) 2021 Dec 22;135(24):2709-2728
Clinical science (London, England : 1979) 2021 Dec 22;135(24):2709-2728
Intracellular H(2)S production is an autophagy-dependent adaptive response to DNA damage.
Jiang X, MacArthur MR, Treviño-Villarreal JH, Kip P, Ozaki CK, Mitchell SJ, Mitchell JR
Cell chemical biology 2021 Dec 16;28(12):1669-1678.e5
Cell chemical biology 2021 Dec 16;28(12):1669-1678.e5
Maternal Separation Induces Long-Term Alterations in the Cardiac Oxytocin Receptor and Cystathionine γ-Lyase Expression in Mice.
Wigger DC, Gröger N, Lesse A, Krause S, Merz T, Gündel H, Braun K, McCook O, Radermacher P, Bock J, Waller C
Oxidative medicine and cellular longevity 2020;2020:4309605
Oxidative medicine and cellular longevity 2020;2020:4309605
Cyanidin-3-O-Glucoside Improves Colonic Motility During Severe Acute Pancreatitis by Inhibiting the H(2)S-Regulated AMPK/mTOR Pathway.
Lian W, Chen W
Drug design, development and therapy 2020;14:3385-3391
Drug design, development and therapy 2020;14:3385-3391
Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner.
Jia G, Yu S, Sun W, Yang J, Wang Y, Qi Y, Chen Y
Frontiers in pharmacology 2020;11:29
Frontiers in pharmacology 2020;11:29
Honokiol ameliorates angiotensin II-induced hypertension and endothelial dysfunction by inhibiting HDAC6-mediated cystathionine γ-lyase degradation.
Chi Z, Le TPH, Lee SK, Guo E, Kim D, Lee S, Seo SY, Lee SY, Kim JH, Lee SY
Journal of cellular and molecular medicine 2020 Sep;24(18):10663-10676
Journal of cellular and molecular medicine 2020 Sep;24(18):10663-10676
Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells.
Sanchez-Aranguren LC, Ahmad S, Dias IHK, Alzahrani FA, Rezai H, Wang K, Ahmed A
Scientific reports 2020 Sep 25;10(1):15810
Scientific reports 2020 Sep 25;10(1):15810
Maternal N-Acetylcysteine Therapy Prevents Hypertension in Spontaneously Hypertensive Rat Offspring: Implications of Hydrogen Sulfide-Generating Pathway and Gut Microbiota.
Hsu CN, Hou CY, Chang-Chien GP, Lin S, Tain YL
Antioxidants (Basel, Switzerland) 2020 Sep 13;9(9)
Antioxidants (Basel, Switzerland) 2020 Sep 13;9(9)
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy UB, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii CM, López LC
Human molecular genetics 2020 Nov 25;29(19):3296-3311
Human molecular genetics 2020 Nov 25;29(19):3296-3311
Inhibition of endogenous hydrogen sulfide biosynthesis enhances the anti-cancer effect of 3,3'-diindolylmethane in human gastric cancer cells.
Ye F, Li X, Sun K, Xu W, Shi H, Bian J, Lu R, Ye Y
Life sciences 2020 Nov 15;261:118348
Life sciences 2020 Nov 15;261:118348
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.
Chen M, Zhou C, Xu H, Zhang T, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109936
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109936
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Xue WL, Chen RQ, Zhang QQ, Li XH, Cao L, Li MY, Li Y, Lin G, Chen Y, Wang MJ, Zhu YC
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2.
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen MN, Dwivedi SKD, Ramchandran R, Mukherjee P, Bhattacharya R
Science advances 2020 Jul;6(27)
Science advances 2020 Jul;6(27)
Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis.
Han Y, Li Y, Hu Z, Wang X, Liu J, Ren X, Yu Y, Li Y, Li W, Sun Y
MicrobiologyOpen 2020 Jan;9(1):e00951
MicrobiologyOpen 2020 Jan;9(1):e00951
Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation.
Bibli SI, Hu J, Leisegang MS, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes RP, Papapetropoulos A, Sigala F, Fleming I
Redox biology 2020 Jan;28:101379
Redox biology 2020 Jan;28:101379
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.
Saini V, Chinta KC, Reddy VP, Glasgow JN, Stein A, Lamprecht DA, Rahman MA, Mackenzie JS, Truebody BE, Adamson JH, Kunota TTR, Bailey SM, Moellering DR, Lancaster JR Jr, Steyn AJC
Nature communications 2020 Jan 28;11(1):557
Nature communications 2020 Jan 28;11(1):557
Endometrial Axin2(+) Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation.
Syed SM, Kumar M, Ghosh A, Tomasetig F, Ali A, Whan RM, Alterman D, Tanwar PS
Cell stem cell 2020 Jan 2;26(1):64-80.e13
Cell stem cell 2020 Jan 2;26(1):64-80.e13
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
De Cicco P, Ercolano G, Rubino V, Terrazzano G, Ruggiero G, Cirino G, Ianaro A
British journal of pharmacology 2020 Feb;177(4):884-897
British journal of pharmacology 2020 Feb;177(4):884-897
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli SI, Thanki K, Resto VA, Chao C, Hellmich MR, Szabo C, Papapetropoulos A, Módis K
British journal of pharmacology 2020 Feb;177(4):866-883
British journal of pharmacology 2020 Feb;177(4):866-883
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, Sun Y, Du H, Wang B, Chen J, Dong S, Lu F, Zhang W
British journal of pharmacology 2020 Feb;177(4):836-856
British journal of pharmacology 2020 Feb;177(4):836-856
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Sikura KÉ, Potor L, Szerafin T, Oros M, Nagy P, Méhes G, Hendrik Z, Zarjou A, Agarwal A, Posta N, Torregrossa R, Whiteman M, Fürtös I, Balla G, Balla J
British journal of pharmacology 2020 Feb;177(4):793-809
British journal of pharmacology 2020 Feb;177(4):793-809
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, Molina H, Garcia-Bermudez J, Pratt DA, Birsoy K
Nature chemical biology 2020 Dec;16(12):1351-1360
Nature chemical biology 2020 Dec;16(12):1351-1360
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
Wang B, Xu T, Li Y, Wang W, Lyu C, Luo D, Yang Q, Ning N, Chen ZJ, Yan J, Chen DB, Li J
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12):e4275-89
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12):e4275-89
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, Li Q, Shu F, Sun Y, Liu N, Peng S, Zhao Y, Dong S, Zhao D, Lu F, Zhang W
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Xu Q, Li Y, Gao X, Kang K, Williams JG, Tong L, Liu J, Ji M, Deterding LJ, Tong X, Locasale JW, Li L, Shats I, Li X
Nature communications 2020 Aug 7;11(1):3978
Nature communications 2020 Aug 7;11(1):3978
Vasorelaxation elicited by endogenous and exogenous hydrogen sulfide in mouse mesenteric arteries.
Hart JL
Naunyn-Schmiedeberg's archives of pharmacology 2020 Apr;393(4):551-564
Naunyn-Schmiedeberg's archives of pharmacology 2020 Apr;393(4):551-564
Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia.
Lai Q, Yuan G, Wang H, Liu Z, Kou J, Yu B, Li F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109820
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109820
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Yu M, Du H, Wang B, Chen J, Lu F, Peng S, Sun Y, Liu N, Sun X, Shiyun D, Zhao Y, Wang Y, Zhao D, Lu F, Zhang W
Aging and disease 2020 Apr;11(2):286-300
Aging and disease 2020 Apr;11(2):286-300
Hydrogen sulfide inhibited L-type calcium channels (CaV1.2) via up-regulation of the channel sulfhydration in vascular smooth muscle cells.
Dai L, Qian Y, Zhou J, Zhu C, Jin L, Li S
European journal of pharmacology 2019 Sep 5;858:172455
European journal of pharmacology 2019 Sep 5;858:172455
17β-Estradiol nongenomically induces vascular endothelial H(2)S release by promoting phosphorylation of cystathionine γ-lyase.
Xu X, Yan Q, Liu X, Li P, Li X, Chen Y, Simoncini T, Liu J, Zhu D, Fu X
The Journal of biological chemistry 2019 Oct 25;294(43):15577-15592
The Journal of biological chemistry 2019 Oct 25;294(43):15577-15592
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Módis K, Ramanujam VS, Govar AA, Lopez E, Anderson KE, Wang R, Szabo C
Biochemical pharmacology 2019 Nov;169:113604
Biochemical pharmacology 2019 Nov;169:113604
Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension.
Shi L, Liu XY, Huang ZG, Ma ZY, Xi Y, Wang LY, Sun NL
Journal of geriatric cardiology : JGC 2019 Nov;16(11):822-834
Journal of geriatric cardiology : JGC 2019 Nov;16(11):822-834
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Zhu J, Berisa M, Schwörer S, Qin W, Cross JR, Thompson CB
Cell metabolism 2019 Nov 5;30(5):865-876.e5
Cell metabolism 2019 Nov 5;30(5):865-876.e5
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, Hui J, Wei A
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Hydrogen sulfide stimulates activation of hepatic stellate cells through increased cellular bio-energetics.
Damba T, Zhang M, Buist-Homan M, van Goor H, Faber KN, Moshage H
Nitric oxide : biology and chemistry 2019 Nov 1;92:26-33
Nitric oxide : biology and chemistry 2019 Nov 1;92:26-33
Hydrogen sulfide regulation of renal and mesenteric blood flow.
Morales-Loredo H, Barrera A, Garcia JM, Pace CE, Naik JS, Gonzalez Bosc LV, Kanagy NL
American journal of physiology. Heart and circulatory physiology 2019 Nov 1;317(5):H1157-H1165
American journal of physiology. Heart and circulatory physiology 2019 Nov 1;317(5):H1157-H1165
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Qin M, Long F, Wu W, Yang D, Huang M, Xiao C, Chen X, Liu X, Zhu YZ
Free radical biology & medicine 2019 Jun;137:99-109
Free radical biology & medicine 2019 Jun;137:99-109
Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
Goren I, Köhler Y, Aglan A, Pfeilschifter J, Beck KF, Frank S
Nitric oxide : biology and chemistry 2019 Jun 1;87:31-42
Nitric oxide : biology and chemistry 2019 Jun 1;87:31-42
S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine γ-lyase-dependent hydrogen sulfide synthesis.
Yadav PK, Vitvitsky V, Kim H, White A, Cho US, Banerjee R
The Journal of biological chemistry 2019 Jul 12;294(28):11011-11022
The Journal of biological chemistry 2019 Jul 12;294(28):11011-11022
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions.
Forsström S, Jackson CB, Carroll CJ, Kuronen M, Pirinen E, Pradhan S, Marmyleva A, Auranen M, Kleine IM, Khan NA, Roivainen A, Marjamäki P, Liljenbäck H, Wang L, Battersby BJ, Richter U, Velagapudi V, Nikkanen J, Euro L, Suomalainen A
Cell metabolism 2019 Dec 3;30(6):1040-1054.e7
Cell metabolism 2019 Dec 3;30(6):1040-1054.e7
Histone deacetylase 6 inhibitor tubastatin A attenuates angiotensin II-induced hypertension by preventing cystathionine γ-lyase protein degradation.
Chi Z, Byeon HE, Seo E, Nguyen QT, Lee W, Jeong Y, Choi J, Pandey D, Berkowitz DE, Kim JH, Lee SY
Pharmacological research 2019 Aug;146:104281
Pharmacological research 2019 Aug;146:104281
Exogenous H(2)S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD(+)-SIRT3 pathway in cardiac tissues of db/db mice.
Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, Lu F, Liu N, Yu M, Peng S, Wang Y, Zhao D, Zhao Y, Ren H, Cheng Z, Dong S, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis.
De Cicco P, Sanders T, Cirino G, Maloy KJ, Ianaro A
Frontiers in immunology 2018;9:499
Frontiers in immunology 2018;9:499
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Zhang GY, Lu D, Duan SF, Gao YR, Liu SY, Hong Y, Dong PZ, Chen YG, Li T, Wang DY, Cheng XS, He F, Wei JS, Li GY, Zhang QY, Wu DD, Ji XY
Oxidative medicine and cellular longevity 2018;2018:9647809
Oxidative medicine and cellular longevity 2018;2018:9647809
Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress.
Chen Y, Jin S, Teng X, Hu Z, Zhang Z, Qiu X, Tian D, Wu Y
Oxidative medicine and cellular longevity 2018;2018:6717212
Oxidative medicine and cellular longevity 2018;2018:6717212
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Potor L, Nagy P, Méhes G, Hendrik Z, Jeney V, Pethő D, Vasas A, Pálinkás Z, Balogh E, Gyetvai Á, Whiteman M, Torregrossa R, Wood ME, Olvasztó S, Nagy P, Balla G, Balla J
Oxidative medicine and cellular longevity 2018;2018:3812568
Oxidative medicine and cellular longevity 2018;2018:3812568
A selective and sensitive method for quantification of endogenous polysulfide production in biological samples.
Bibli SI, Luck B, Zukunft S, Wittig J, Chen W, Xian M, Papapetropoulos A, Hu J, Fleming I
Redox biology 2018 Sep;18:295-304
Redox biology 2018 Sep;18:295-304
Intermittent hypoxia exacerbates increased blood pressure in rats with chronic kidney disease.
Riggs JL, Pace CE, Ward HH, Gonzalez Bosc LV, Rios L, Barrera A, Kanagy NL
American journal of physiology. Renal physiology 2018 Oct 1;315(4):F927-F941
American journal of physiology. Renal physiology 2018 Oct 1;315(4):F927-F941
Alpha-lipoic acid regulates the autophagy of vascular smooth muscle cells in diabetes by elevating hydrogen sulfide level.
Qiu X, Liu K, Xiao L, Jin S, Dong J, Teng X, Guo Q, Chen Y, Wu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3723-3738
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3723-3738
Role for Cystathionine γ Lyase (CSE) in an Ethanol (E)-Induced Lesion in Fetal Brain GSH Homeostasis.
Patel D, Rathinam M, Jarvis C, Mahimainathan L, Henderson G, Narasimhan M
International journal of molecular sciences 2018 May 22;19(5)
International journal of molecular sciences 2018 May 22;19(5)
Drug resistance induces the upregulation of H(2)S-producing enzymes in HCT116 colon cancer cells.
Untereiner AA, Pavlidou A, Druzhyna N, Papapetropoulos A, Hellmich MR, Szabo C
Biochemical pharmacology 2018 Mar;149:174-185
Biochemical pharmacology 2018 Mar;149:174-185
Endogenous H(2)S sensitizes PAR4-induced bladder pain.
Wang W, Bo Q, Du J, Yu X, Zhu K, Cui J, Zhao H, Wang Y, Shi B, Zhu Y
American journal of physiology. Renal physiology 2018 Jun 1;314(6):F1077-F1086
American journal of physiology. Renal physiology 2018 Jun 1;314(6):F1077-F1086
Early Supplementation of d-Cysteine or l-Cysteine Prevents Hypertension and Kidney Damage in Spontaneously Hypertensive Rats Exposed to High-Salt Intake.
Hsu CN, Lin YJ, Lu PC, Tain YL
Molecular nutrition & food research 2018 Jan;62(2)
Molecular nutrition & food research 2018 Jan;62(2)
Reduced adipose tissue H(2)S in obesity.
Katsouda A, Szabo C, Papapetropoulos A
Pharmacological research 2018 Feb;128:190-199
Pharmacological research 2018 Feb;128:190-199
Diurnal Fluctuations in Plasma Hydrogen Sulfide of the Mice.
Jin S, Tan B, Teng X, Meng R, Jiao X, Tian D, Xiao L, Xue H, Guo Q, Duan X, Wu Y
Frontiers in pharmacology 2017;8:682
Frontiers in pharmacology 2017;8:682
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Peng J, Tang ZH, Ren Z, He B, Zeng Y, Liu LS, Wang Z, Wei DH, Zheng XL, Jiang ZS
Frontiers in pharmacology 2017;8:486
Frontiers in pharmacology 2017;8:486
Hydrogen sulfide improves diabetic wound healing in ob/ob mice via attenuating inflammation.
Zhao H, Lu S, Chai J, Zhang Y, Ma X, Chen J, Guan Q, Wan M, Liu Y
Journal of diabetes and its complications 2017 Sep;31(9):1363-1369
Journal of diabetes and its complications 2017 Sep;31(9):1363-1369
Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway.
You J, Shi X, Liang H, Ye J, Wang L, Han H, Fang H, Kang W, Wang T
Oncotarget 2017 Sep 12;8(39):65677-65686
Oncotarget 2017 Sep 12;8(39):65677-65686
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Magierowski M, Magierowska K, Surmiak M, Hubalewska-Mazgaj M, Kwiecien S, Wallace JL, Brzozowski T
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Oct;68(5):749-756
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Oct;68(5):749-756
Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide.
Nalli AD, Wang H, Bhattacharya S, Blakeney BA, Murthy KS
Pharmacology research & perspectives 2017 Oct;5(5)
Pharmacology research & perspectives 2017 Oct;5(5)
Augmentation of cGMP/PKG pathway and colonic motility by hydrogen sulfide.
Nalli AD, Bhattacharya S, Wang H, Kendig DM, Grider JR, Murthy KS
American journal of physiology. Gastrointestinal and liver physiology 2017 Oct 1;313(4):G330-G341
American journal of physiology. Gastrointestinal and liver physiology 2017 Oct 1;313(4):G330-G341
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K, Szabo C, Chao C, Hellmich MR
Cancer research 2017 Nov 1;77(21):5741-5754
Cancer research 2017 Nov 1;77(21):5741-5754
Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency.
Wang P, Wu L, Ju Y, Fu M, Shuang T, Qian Z, Wang R
Antioxidants & redox signaling 2017 Nov 1;27(13):931-944
Antioxidants & redox signaling 2017 Nov 1;27(13):931-944
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Zhang Z, Jin S, Teng X, Duan X, Chen Y, Wu Y
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Production of endogenous hydrogen sulfide in human gingival tissue.
Chun-Mei J, Wu C, Guo-Liang M, Yue G, Ning C, Ji Y
Archives of oral biology 2017 Feb;74:108-113
Archives of oral biology 2017 Feb;74:108-113
Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection.
Bibli SI, Szabo C, Chatzianastasiou A, Luck B, Zukunft S, Fleming I, Papapetropoulos A
Molecular pharmacology 2017 Dec;92(6):718-730
Molecular pharmacology 2017 Dec;92(6):718-730
Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock.
Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O
Intensive care medicine experimental 2017 Dec;5(1):30
Intensive care medicine experimental 2017 Dec;5(1):30
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, Zhao Y, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
Ahmad A, Druzhyna N, Szabo C
Burns : journal of the International Society for Burn Injuries 2017 Aug;43(5):1021-1033
Burns : journal of the International Society for Burn Injuries 2017 Aug;43(5):1021-1033
Reciprocal regulation of eNOS, H(2)S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin.
Sigala F, Efentakis P, Karageorgiadi D, Filis K, Zampas P, Iliodromitis EK, Zografos G, Papapetropoulos A, Andreadou I
Redox biology 2017 Aug;12:70-81
Redox biology 2017 Aug;12:70-81
Role of thiosulfate in hydrogen sulfide-dependent redox signaling in endothelial cells.
Leskova A, Pardue S, Glawe JD, Kevil CG, Shen X
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H256-H264
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H256-H264
mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression.
Khan NA, Nikkanen J, Yatsuga S, Jackson C, Wang L, Pradhan S, Kivelä R, Pessia A, Velagapudi V, Suomalainen A
Cell metabolism 2017 Aug 1;26(2):419-428.e5
Cell metabolism 2017 Aug 1;26(2):419-428.e5
Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.
Lu L, Kingdom J, Burton GJ, Cindrova-Davies T
The American journal of pathology 2017 Apr;187(4):908-920
The American journal of pathology 2017 Apr;187(4):908-920
Protective effects of hydrogen sulfide against angiotensin II-induced endoplasmic reticulum stress in HUVECs.
Hu HJ, Jiang ZS, Qiu J, Zhou SH, Liu QM
Molecular medicine reports 2017 Apr;15(4):2213-2222
Molecular medicine reports 2017 Apr;15(4):2213-2222
NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to intermittent hypoxia.
Gonzalez Bosc LV, Osmond JM, Giermakowska WK, Pace CE, Riggs JL, Jackson-Weaver O, Kanagy NL
American journal of physiology. Heart and circulatory physiology 2017 Apr 1;312(4):H791-H799
American journal of physiology. Heart and circulatory physiology 2017 Apr 1;312(4):H791-H799
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway.
Li W, Ma F, Zhang L, Huang Y, Li X, Zhang A, Hou C, Zhu Y, Zhu Y
Oxidative medicine and cellular longevity 2016;2016:4690857
Oxidative medicine and cellular longevity 2016;2016:4690857
Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock.
Stenzel T, Weidgang C, Wagner K, Wagner F, Gröger M, Weber S, Stahl B, Wachter U, Vogt J, Calzia E, Denk S, Georgieff M, Huber-Lang M, Radermacher P, McCook O
Shock (Augusta, Ga.) 2016 Oct;46(4):398-404
Shock (Augusta, Ga.) 2016 Oct;46(4):398-404
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N(G)-Nitro-L-arginine-methyl ester (L-NAME)-induced fetal programming of hypertension in adult male offspring.
Tain YL, Lee CT, Chan JY, Hsu CN
American journal of obstetrics and gynecology 2016 Nov;215(5):636.e1-636.e72
American journal of obstetrics and gynecology 2016 Nov;215(5):636.e1-636.e72
The novel H(2) S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.
Marino A, Martelli A, Citi V, Fu M, Wang R, Calderone V, Levi R
British journal of pharmacology 2016 Nov;173(22):3222-3234
British journal of pharmacology 2016 Nov;173(22):3222-3234
Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway.
Bing W, Pang X, Qu Q, Bai X, Yang W, Bi Y, Bi X
Journal of cellular and molecular medicine 2016 May;20(5):949-61
Journal of cellular and molecular medicine 2016 May;20(5):949-61
Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction.
Zhang Y, Yang J, Wang T, Wang SG, Liu JH, Yin CP, Ye ZQ
The journal of sexual medicine 2016 Mar;13(3):350-60
The journal of sexual medicine 2016 Mar;13(3):350-60
Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.
Saha S, Chakraborty PK, Xiong X, Dwivedi SK, Mustafi SB, Leigh NR, Ramchandran R, Mukherjee P, Bhattacharya R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Jan;30(1):441-56
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Jan;30(1):441-56
Radiation Exposure Promotes Hepatocarcinoma Cell Invasion through Epithelial Mesenchymal Transition Mediated by H2S/CSE Pathway.
Pan Y, Zhou C, Yuan D, Zhang J, Shao C
Radiation research 2016 Jan;185(1):96-105
Radiation research 2016 Jan;185(1):96-105
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting the expression of peroxiredoxin III in H9c2 cells.
Liu MH, Lin XL, Yuan C, He J, Tan TP, Wu SJ, Yu S, Chen L, Liu J, Tian W, Chen YD, Fu HY, Li J, Zhang Y
Molecular medicine reports 2016 Jan;13(1):367-72
Molecular medicine reports 2016 Jan;13(1):367-72
MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery.
Kuo MM, Kim DH, Jandu S, Bergman Y, Tan S, Wang H, Pandey DR, Abraham TP, Shoukas AA, Berkowitz DE, Santhanam L
American journal of physiology. Heart and circulatory physiology 2016 Jan 1;310(1):H71-9
American journal of physiology. Heart and circulatory physiology 2016 Jan 1;310(1):H71-9
Maternal N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and prevents programmed hypertension in male offspring exposed to prenatal dexamethasone and postnatal high-fat diet.
Tai IH, Sheen JM, Lin YJ, Yu HR, Tiao MM, Chen CC, Huang LT, Tain YL
Nitric oxide : biology and chemistry 2016 Feb 29;53:6-12
Nitric oxide : biology and chemistry 2016 Feb 29;53:6-12
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase.
Ahmad A, Gerö D, Olah G, Szabo C
International journal of molecular medicine 2016 Dec;38(6):1683-1692
International journal of molecular medicine 2016 Dec;38(6):1683-1692
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.
Ahmad A, Druzhyna N, Szabo C
Shock (Augusta, Ga.) 2016 Aug;46(2):183-93
Shock (Augusta, Ga.) 2016 Aug;46(2):183-93
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.
Nikkanen J, Forsström S, Euro L, Paetau I, Kohnz RA, Wang L, Chilov D, Viinamäki J, Roivainen A, Marjamäki P, Liljenbäck H, Ahola S, Buzkova J, Terzioglu M, Khan NA, Pirnes-Karhu S, Paetau A, Lönnqvist T, Sajantila A, Isohanni P, Tyynismaa H, Nomura DK, Battersby BJ, Velagapudi V, Carroll CJ, Suomalainen A
Cell metabolism 2016 Apr 12;23(4):635-48
Cell metabolism 2016 Apr 12;23(4):635-48
Effects of hydrogen sulfide on high glucose-induced glomerular podocyte injury in mice.
Liu Y, Zhao H, Qiang Y, Qian G, Lu S, Chen J, Wang X, Guan Q, Liu Y, Fu Y
International journal of clinical and experimental pathology 2015;8(6):6814-20
International journal of clinical and experimental pathology 2015;8(6):6814-20
Neuroprotective effects of hydrogen sulfide in Parkinson's disease animal models: methods and protocols.
Xue X, Bian JS
Methods in enzymology 2015;554:169-86
Methods in enzymology 2015;554:169-86
Mitochondria-targeted hydrogen sulfide donor AP39 improves neurological outcomes after cardiac arrest in mice.
Ikeda K, Marutani E, Hirai S, Wood ME, Whiteman M, Ichinose F
Nitric oxide : biology and chemistry 2015 Sep 15;49:90-6
Nitric oxide : biology and chemistry 2015 Sep 15;49:90-6
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
Syhr KMJ, Boosen M, Hohmann SW, Longen S, Köhler Y, Pfeilschifter J, Beck KF, Geisslinger G, Schmidtko A, Kallenborn-Gerhardt W
Brain research 2015 Oct 22;1624:380-389
Brain research 2015 Oct 22;1624:380-389
H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells.
Ju Y, Untereiner A, Wu L, Yang G
Biochimica et biophysica acta 2015 Nov;1850(11):2293-303
Biochimica et biophysica acta 2015 Nov;1850(11):2293-303
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes.
Liu MH, Lin XL, Zhang Y, He J, Tan TP, Wu SJ, Liu J, Tian W, Chen L, Yu S, Li J, Yuan C
Molecular medicine reports 2015 Nov;12(5):6841-8
Molecular medicine reports 2015 Nov;12(5):6841-8
Role of cystathionine beta synthase in lipid metabolism in ovarian cancer.
Chakraborty PK, Xiong X, Mustafi SB, Saha S, Dhanasekaran D, Mandal NA, McMeekin S, Bhattacharya R, Mukherjee P
Oncotarget 2015 Nov 10;6(35):37367-84
Oncotarget 2015 Nov 10;6(35):37367-84
Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S.
Salloum FN, Sturz GR, Yin C, Rehman S, Hoke NN, Kukreja RC, Xi L
Experimental biology and medicine (Maywood, N.J.) 2015 May;240(5):669-81
Experimental biology and medicine (Maywood, N.J.) 2015 May;240(5):669-81
Evidence for a functional vasodilatatory role for hydrogen sulphide in the human cutaneous microvasculature.
Kutz JL, Greaney JL, Santhanam L, Alexander LM
The Journal of physiology 2015 May 1;593(9):2121-9
The Journal of physiology 2015 May 1;593(9):2121-9
Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells.
Nalli AD, Rajagopal S, Mahavadi S, Grider JR, Murthy KS
American journal of physiology. Cell physiology 2015 Mar 15;308(6):C485-95
American journal of physiology. Cell physiology 2015 Mar 15;308(6):C485-95
Hydrogen sulfide is essential for Schwann cell responses to peripheral nerve injury.
Park BS, Kim HW, Rhyu IJ, Park C, Yeo SG, Huh Y, Jeong NY, Jung J
Journal of neurochemistry 2015 Jan;132(2):230-42
Journal of neurochemistry 2015 Jan;132(2):230-42
Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.
Coletta C, Módis K, Szczesny B, Brunyánszki A, Oláh G, Rios EC, Yanagi K, Ahmad A, Papapetropoulos A, Szabo C
Molecular medicine (Cambridge, Mass.) 2015 Feb 18;21(1):1-14
Molecular medicine (Cambridge, Mass.) 2015 Feb 18;21(1):1-14
Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia-inducible factor-1α.
Flannigan KL, Agbor TA, Motta JP, Ferraz JG, Wang R, Buret AG, Wallace JL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Apr;29(4):1591-602
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Apr;29(4):1591-602
Hydrogen sulfide-induced enhancement of gastric fundus smooth muscle tone is mediated by voltage-dependent potassium and calcium channels in mice.
Meng XM, Huang X, Zhang CM, Liu DH, Lu HL, Kim YC, Xu WX
World journal of gastroenterology 2015 Apr 28;21(16):4840-51
World journal of gastroenterology 2015 Apr 28;21(16):4840-51
The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide.
Altaany Z, Ju Y, Yang G, Wang R
Science signaling 2014 Sep 9;7(342):ra87
Science signaling 2014 Sep 9;7(342):ra87
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.
Jurkowska H, Roman HB, Hirschberger LL, Sasakura K, Nagano T, Hanaoka K, Krijt J, Stipanuk MH
Amino acids 2014 May;46(5):1353-65
Amino acids 2014 May;46(5):1353-65
S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair.
Zhao K, Ju Y, Li S, Altaany Z, Wang R, Yang G
EMBO reports 2014 Jul;15(7):792-800
EMBO reports 2014 Jul;15(7):792-800
Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons.
Miyamoto R, Otsuguro K, Yamaguchi S, Ito S
Journal of neurochemistry 2014 Jul;130(1):29-40
Journal of neurochemistry 2014 Jul;130(1):29-40
Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism.
Flannigan KL, Ferraz JG, Wang R, Wallace JL
PloS one 2013;8(8):e71962
PloS one 2013;8(8):e71962
Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance.
Bhattacharyya S, Saha S, Giri K, Lanza IR, Nair KS, Jennings NB, Rodriguez-Aguayo C, Lopez-Berestein G, Basal E, Weaver AL, Visscher DW, Cliby W, Sood AK, Bhattacharya R, Mukherjee P
PloS one 2013;8(11):e79167
PloS one 2013;8(11):e79167
H2 S inhibits the activation of hepatic stellate cells and downregulates the expression of urotensin II.
Liu Y, Li Y, Yang W, Cao G
Hepatology research : the official journal of the Japan Society of Hepatology 2013 Jun;43(6):670-8
Hepatology research : the official journal of the Japan Society of Hepatology 2013 Jun;43(6):670-8
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).
Asimakopoulou A, Panopoulos P, Chasapis CT, Coletta C, Zhou Z, Cirino G, Giannis A, Szabo C, Spyroulias GA, Papapetropoulos A
British journal of pharmacology 2013 Jun;169(4):922-32
British journal of pharmacology 2013 Jun;169(4):922-32
Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells.
Altaany Z, Yang G, Wang R
Journal of cellular and molecular medicine 2013 Jul;17(7):879-88
Journal of cellular and molecular medicine 2013 Jul;17(7):879-88
Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress.
Bos EM, Wang R, Snijder PM, Boersema M, Damman J, Fu M, Moser J, Hillebrands JL, Ploeg RJ, Yang G, Leuvenink HG, van Goor H
Journal of the American Society of Nephrology : JASN 2013 Apr;24(5):759-70
Journal of the American Society of Nephrology : JASN 2013 Apr;24(5):759-70
The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma.
Zhang G, Wang P, Yang G, Cao Q, Wang R
The American journal of pathology 2013 Apr;182(4):1188-95
The American journal of pathology 2013 Apr;182(4):1188-95
Suppression of endogenous hydrogen sulfide contributes to the radiation-induced bystander effects on hypoxic HepG2 cells.
Zhang J, Xie Y, Xu Y, Shao C
Radiation research 2012 Nov;178(5):395-402
Radiation research 2012 Nov;178(5):395-402
Is cystathionine gamma-lyase protein expressed in the heart?
Fu M, Zhang W, Yang G, Wang R
Biochemical and biophysical research communications 2012 Nov 30;428(4):469-74
Biochemical and biophysical research communications 2012 Nov 30;428(4):469-74
Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism.
Hassan MI, Boosen M, Schaefer L, Kozlowska J, Eisel F, von Knethen A, Beck M, Hemeida RA, El-Moselhy MA, Hamada FM, Beck KF, Pfeilschifter J
British journal of pharmacology 2012 Aug;166(8):2231-42
British journal of pharmacology 2012 Aug;166(8):2231-42
Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress.
Wang XY, Yang CT, Zheng DD, Mo LQ, Lan AP, Yang ZL, Hu F, Chen PX, Liao XX, Feng JQ
Molecular and cellular biochemistry 2012 Apr;363(1-2):419-26
Molecular and cellular biochemistry 2012 Apr;363(1-2):419-26
Hydrogen sulfide contributes to hypoxia-induced radioresistance on hepatoma cells.
Zhang J, Xie Y, Xu Y, Pan Y, Shao C
Journal of radiation research 2011;52(5):622-8
Journal of radiation research 2011;52(5):622-8
Hydrogen Sulfide in the RVLM and PVN has No Effect on Cardiovascular Regulation.
Streeter E, Al-Magableh M, Hart JL, Badoer E
Frontiers in physiology 2011;2:55
Frontiers in physiology 2011;2:55
Cadmium induced radioadaptive response via an ATM-independent H(2)S/cystathionine γ-lyase modulation.
Pan Y, Yuan D, Zhang J, Shao C
Mutation research 2011 Feb 10;707(1-2):67-73
Mutation research 2011 Feb 10;707(1-2):67-73
Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta.
Al-Magableh MR, Hart JL
Naunyn-Schmiedeberg's archives of pharmacology 2011 Apr;383(4):403-13
Naunyn-Schmiedeberg's archives of pharmacology 2011 Apr;383(4):403-13
The dual role of the cystathionine gamma-lyase/hydrogen sulfide pathway in CVB3-induced myocarditis in mice.
Hua W, Jiang J, Rong X, Wu R, Qiu H, Zhang Y, Chen Q
Biochemical and biophysical research communications 2009 Oct 23;388(3):595-600
Biochemical and biophysical research communications 2009 Oct 23;388(3):595-600
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 12217-1-AP(CSE antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CSE (IP:12217-1-AP, 3ug; Detection:12217-1-AP 1:1000) with HEK-293 cells lysate 2700ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Gamma cystathionase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Gamma cystathionase. This antibody recognizes human,mouse,rat antigen. The Gamma cystathionase antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
