ABIN560521

antibody from antibodies-online

Targeting: CTH

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN560521

Provider

antibodies-online

Product name

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405), (full length) antibody

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Epitope

AA 1-405, full length

Isotype

IgG

Antibody clone number

4E1-1B7

Vial size

100 μg

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Handling

Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.

Li JJ, Li Q, Du HP, Wang YL, You SJ, Wang F, Xu XS, Cheng J, Cao YJ, Liu CF, Hu LF
International journal of molecular sciences 2015 Jun 3;16(6):12560-77

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Statins upregulate cystathionine γ-lyase transcription and H2S generation via activating Akt signaling in macrophage.

Xu Y, Du HP, Li J, Xu R, Wang YL, You SJ, Liu H, Wang F, Cao YJ, Liu CF, Hu LF
Pharmacological research 2014 Sep;87:18-25

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Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.

Ida T, Sawa T, Ihara H, Tsuchiya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S, Matsunaga T, Yamamoto M, Ono K, Devarie-Baez NO, Xian M, Fukuto JM, Akaike T
Proceedings of the National Academy of Sciences of the United States of America 2014 May 27;111(21):7606-11

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Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells.

Badiei A, Rivers-Auty J, Ang AD, Bhatia M
Applied microbiology and biotechnology 2013 Sep;97(17):7845-52

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Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.

Yang G, Zhao K, Ju Y, Mani S, Cao Q, Puukila S, Khaper N, Wu L, Wang R
Antioxidants & redox signaling 2013 May 20;18(15):1906-19

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Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis.

Mani S, Li H, Untereiner A, Wu L, Yang G, Austin RC, Dickhout JG, Lhoták Š, Meng QH, Wang R
Circulation 2013 Jun 25;127(25):2523-34

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Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe.

Dufton N, Natividad J, Verdu EF, Wallace JL
Scientific reports 2012;2:499

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MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells.

Yang G, Pei Y, Cao Q, Wang R
Journal of cellular physiology 2012 Sep;227(9):3192-200

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Is cystathionine gamma-lyase protein expressed in the heart?

Fu M, Zhang W, Yang G, Wang R
Biochemical and biophysical research communications 2012 Nov 30;428(4):469-74

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Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells.

Yang G, Li H, Tang G, Wu L, Zhao K, Cao Q, Xu C, Wang R
Journal of molecular and cellular cardiology 2012 Mar;52(3):677-88

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Hydrogen sulfide producing enzymes in pregnancy and preeclampsia.

Holwerda KM, Bos EM, Rajakumar A, Ris-Stalpers C, van Pampus MG, Timmer A, Erwich JJ, Faas MM, van Goor H, Lely AT
Placenta 2012 Jun;33(6):518-21

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Hydrogen sulfide modulates contractile function in rat jejunum.

Kasparek MS, Linden DR, Farrugia G, Sarr MG
The Journal of surgical research 2012 Jun 15;175(2):234-42

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Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α.

Wu B, Teng H, Yang G, Wu L, Wang R
British journal of pharmacology 2012 Dec;167(7):1492-505

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Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model.

Li X, Mao XB, Hei RY, Zhang ZB, Wen LT, Zhang PZ, Qiu JH, Qiao L
PloS one 2011;6(10):e26728

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Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells.

Yang G, Pei Y, Teng H, Cao Q, Wang R
The Journal of biological chemistry 2011 Jul 29;286(30):26450-60

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Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract.

Martin GR, McKnight GW, Dicay MS, Coffin CS, Ferraz JG, Wallace JL
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2010 Feb;42(2):103-9

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Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator.

Feng X, Chen Y, Zhao J, Tang C, Jiang Z, Geng B
Biochemical and biophysical research communications 2009 Feb 27;380(1):153-9

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Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.

Wallace JL, Vong L, McKnight W, Dicay M, Martin GR
Gastroenterology 2009 Aug;137(2):569-78, 578.e1

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Hydrogen sulfide protects rat lung from ischemia-reperfusion injury.

Fu Z, Liu X, Geng B, Fang L, Tang C
Life sciences 2008 Jun 6;82(23-24):1196-202

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Hydrogen sulfide enhances ulcer healing in rats.

Wallace JL, Dicay M, McKnight W, Martin GR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Dec;21(14):4070-6

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Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon.

Schicho R, Krueger D, Zeller F, Von Weyhern CW, Frieling T, Kimura H, Ishii I, De Giorgio R, Campi B, Schemann M
Gastroenterology 2006 Nov;131(5):1542-52

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

ELISA

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

ELISA