Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- MAB2329 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2329, RRID:AB_10629567
- Product name
- DEFA5 monoclonal antibody, clone 8C8
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant DEFA5.
- Isotype
- IgG
- Antibody clone number
- 8C8
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues.
Reduced Paneth cell alpha-defensins in ileal Crohn's disease.
Localization of human intestinal defensin 5 in Paneth cell granules.
Wehkamp J, Chu H, Shen B, Feathers RW, Kays RJ, Lee SK, Bevins CL
FEBS letters 2006 Oct 2;580(22):5344-50
FEBS letters 2006 Oct 2;580(22):5344-50
Reduced Paneth cell alpha-defensins in ileal Crohn's disease.
Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H Jr, Fellermann K, Ganz T, Stange EF, Bevins CL
Proceedings of the National Academy of Sciences of the United States of America 2005 Dec 13;102(50):18129-34
Proceedings of the National Academy of Sciences of the United States of America 2005 Dec 13;102(50):18129-34
Localization of human intestinal defensin 5 in Paneth cell granules.
Porter EM, Liu L, Oren A, Anton PA, Ganz T
Infection and immunity 1997 Jun;65(6):2389-95
Infection and immunity 1997 Jun;65(6):2389-95
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using DEFA5 monoclonal antibody, clone 8C8 (Cat # MAB2329).
- Validation comment
- Immunohistochemistry