ABIN497988
antibody from antibodies-online
Targeting: ATG16L1
APG16L, ATG16A, ATG16L, FLJ10035, WDR30
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
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Validation data
Reference
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- Product number
- ABIN497988 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- ATG16 antibody was raised against a 18 amino acid peptide from near the amino terminus of Human ATG16 (Genbank accession No. NP_110430).
- Description
- Immunoaffinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Autophagy as a cell death and tumor suppressor mechanism.
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.
Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.
Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, Natsume T, Ohsumi Y, Yoshimori T
Journal of cell science 2003 May 1;116(Pt 9):1679-88
Journal of cell science 2003 May 1;116(Pt 9):1679-88
Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y
The Journal of cell biology 2000 Sep 18;150(6):1507-13
The Journal of cell biology 2000 Sep 18;150(6):1507-13
Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Mizushima N, Noda T, Ohsumi Y
The EMBO journal 1999 Jul 15;18(14):3888-96
The EMBO journal 1999 Jul 15;18(14):3888-96
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5
Carcinogenesis 1993 Dec;14(12):2501-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20063PU-N ATG16 antibody staining of HeLa Cell Lysate by Western Blotting at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20063PU-N ATG16 antibody staining of HeLa Cell Lysate by Immunofluorescence at 4.75 ?g/ml.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20063PU-N ATG16 antibody staining of HeLa Cell Lysate by Immunocytochemistry at 2 ?g/ml.