ABIN1881524
antibody from antibodies-online
Targeting: MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881524 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (pSer12) antibody
- Antibody type
- Polyclonal
- Antigen
- This MAP1LC3A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of human MAP1LC3A.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer12
- Antibody clone number
- RB30640
- Vial size
- 400 μL
- Concentration
- 0.27 mg/mL
Submitted references p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.
Protein kinase C inhibits autophagy and phosphorylates LC3.
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.
Regulation of the autophagy protein LC3 by phosphorylation.
Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z, Oren M
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 26;107(43):18511-6
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 26;107(43):18511-6
Protein kinase C inhibits autophagy and phosphorylates LC3.
Jiang H, Cheng D, Liu W, Peng J, Feng J
Biochemical and biophysical research communications 2010 May 14;395(4):471-6
Biochemical and biophysical research communications 2010 May 14;395(4):471-6
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.
Namgoong GM, Khanal P, Cho HG, Lim SC, Oh YK, Kang BS, Shim JH, Yoo JC, Choi HS
The Journal of biological chemistry 2010 Jul 30;285(31):23829-41
The Journal of biological chemistry 2010 Jul 30;285(31):23829-41
Regulation of the autophagy protein LC3 by phosphorylation.
Cherra SJ 3rd, Kulich SM, Uechi G, Balasubramani M, Mountzouris J, Day BW, Chu CT
The Journal of cell biology 2010 Aug 23;190(4):533-9
The Journal of cell biology 2010 Aug 23;190(4):533-9
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- Dot blot analysis of MAP1LC3A Antibody (Phospho S12) Phospho-specific Pab (ABIN1881524) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 μg per mL.