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- References [11]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 18722-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18722-1-AP, RRID:AB_10597104
- Product name
- LC3A-Specific antibody
- Antibody type
- Polyclonal
- Description
- LC3A-Specific antibody (Cat. #18722-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Tcap Deficiency in Zebrafish Leads to ROS Production and Mitophagy, and Idebenone Improves its Phenotypes.
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats.
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Autophagy Triggered by Oxidative Stress Appears to Be Mediated by the AKT/mTOR Signaling Pathway in the Liver of Sleep-Deprived Rats.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy.
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
He S, Shi Y, Ye J, Yin J, Yang Y, Liu D, Shen T, Zeng D, Zhang M, Li S, Xu F, Cai Y, Zhao F, Li H, Peng D
Translational psychiatry 2023 Nov 25;13(1):362
Translational psychiatry 2023 Nov 25;13(1):362
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Zhang L, Zhang X, Che D, Zeng L, Zhang Y, Nan K, Zhang X, Zhang H, Guo Z
Phytotherapy research : PTR 2023 Jan;37(1):124-139
Phytotherapy research : PTR 2023 Jan;37(1):124-139
Tcap Deficiency in Zebrafish Leads to ROS Production and Mitophagy, and Idebenone Improves its Phenotypes.
Lv X, Zhang R, Xu L, Wang G, Yan C, Lin P
Frontiers in cell and developmental biology 2022;10:836464
Frontiers in cell and developmental biology 2022;10:836464
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
Gottschalk G, Peterson D, Knox K, Maynard M, Whelan RJ, Roy A
Molecular and cellular neurosciences 2022 May;120:103731
Molecular and cellular neurosciences 2022 May;120:103731
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Mei J, Sheng X, Yan Y, Cai X, Zhang C, Tian J, Zhang M, Zhou J, Shan H, Huang C
BMC molecular and cell biology 2022 Jun 27;23(1):24
BMC molecular and cell biology 2022 Jun 27;23(1):24
Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats.
Li Y, Zhang W, Liu M, Zhang Q, Lin Z, Jia M, Liu D, Lin L
Oxidative medicine and cellular longevity 2021;2021:5645090
Oxidative medicine and cellular longevity 2021;2021:5645090
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Li J, Xie J, Wang YZ, Gan YR, Wei L, Ding GW, Ding YH, Xie DX
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Autophagy Triggered by Oxidative Stress Appears to Be Mediated by the AKT/mTOR Signaling Pathway in the Liver of Sleep-Deprived Rats.
Li Y, Zhang Y, Ji G, Shen Y, Zhao N, Liang Y, Wang Z, Liu M, Lin L
Oxidative medicine and cellular longevity 2020;2020:6181630
Oxidative medicine and cellular longevity 2020;2020:6181630
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy.
Kessel D, Evans CL
Photochemistry and photobiology 2016 Jul;92(4):620-3
Photochemistry and photobiology 2016 Jul;92(4):620-3
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Zhu X, Ruan Z, Yang X, Chu K, Wu H, Li Y, Huang Y
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 18722-1-AP(LC3-Specific antibody) at dilution of 1:1500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MAP1LC3A antibody 18722-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
