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LearnABIN2838028
antibody from antibodies-online
Targeting: MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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- Product number
- ABIN2838028 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-LC3 (APG8) (full length) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- full length
- Isotype
- IgG
- Antibody clone number
- 166AT1234
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors.
GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells.
CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism.
Atorvastatin induces autophagic cell death in prostate cancer cells in vitro.
The effect of RNAi silencing of p62 using an osmotic polysorbitol transporter on autophagy and tumorigenesis in lungs of K-rasLA1 mice.
Induction of autophagy is essential for monocyte-macrophage differentiation.
Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction.
Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy.
Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis.
Protein kinase C inhibits autophagy and phosphorylates LC3.
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.
Processing of autophagic protein LC3 by the 20S proteasome.
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition.
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation.
Intracellular localization of GASP/ECOP/VOPP1.
The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras.
Rabionet M, Bayerle A, Jennemann R, Heid H, Fuchser J, Marsching C, Porubsky S, Bolenz C, Guillou F, Gröne HJ, Gorgas K, Sandhoff R
Human molecular genetics 2015 Sep 1;24(17):4792-808
Human molecular genetics 2015 Sep 1;24(17):4792-808
GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells.
Hsin IL, Ou CC, Wu MF, Jan MS, Hsiao YM, Lin CH, Ko JL
Molecular pharmaceutics 2015 May 4;12(5):1534-43
Molecular pharmaceutics 2015 May 4;12(5):1534-43
CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism.
Vlahava VM, Eliopoulos AG, Sourvinos G
Cellular signalling 2015 Jun;27(6):1253-63
Cellular signalling 2015 Jun;27(6):1253-63
Atorvastatin induces autophagic cell death in prostate cancer cells in vitro.
He Z, Yuan J, Qi P, Zhang L, Wang Z
Molecular medicine reports 2015 Jun;11(6):4403-8
Molecular medicine reports 2015 Jun;11(6):4403-8
The effect of RNAi silencing of p62 using an osmotic polysorbitol transporter on autophagy and tumorigenesis in lungs of K-rasLA1 mice.
Islam MA, Shin JY, Yun CH, Cho CS, Seo HW, Chae C, Cho MH
Biomaterials 2014 Feb;35(5):1584-96
Biomaterials 2014 Feb;35(5):1584-96
Induction of autophagy is essential for monocyte-macrophage differentiation.
Zhang Y, Morgan MJ, Chen K, Choksi S, Liu ZG
Blood 2012 Mar 22;119(12):2895-905
Blood 2012 Mar 22;119(12):2895-905
Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction.
Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, Li C, Fan Y, Yu J, Pei Z, Zeng J
Autophagy 2012 Jan;8(1):63-76
Autophagy 2012 Jan;8(1):63-76
Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy.
Zhou D, Kang KH, Spector SA
The Journal of infectious diseases 2012 Apr 15;205(8):1258-67
The Journal of infectious diseases 2012 Apr 15;205(8):1258-67
Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis.
Song D, Lee FS
The Journal of biological chemistry 2011 May 6;286(18):15797-805
The Journal of biological chemistry 2011 May 6;286(18):15797-805
Protein kinase C inhibits autophagy and phosphorylates LC3.
Jiang H, Cheng D, Liu W, Peng J, Feng J
Biochemical and biophysical research communications 2010 May 14;395(4):471-6
Biochemical and biophysical research communications 2010 May 14;395(4):471-6
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.
Namgoong GM, Khanal P, Cho HG, Lim SC, Oh YK, Kang BS, Shim JH, Yoo JC, Choi HS
The Journal of biological chemistry 2010 Jul 30;285(31):23829-41
The Journal of biological chemistry 2010 Jul 30;285(31):23829-41
Processing of autophagic protein LC3 by the 20S proteasome.
Gao Z, Gammoh N, Wong PM, Erdjument-Bromage H, Tempst P, Jiang X
Autophagy 2010 Jan;6(1):126-37
Autophagy 2010 Jan;6(1):126-37
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG
The Journal of clinical investigation 2010 Jan;120(1):127-41
The Journal of clinical investigation 2010 Jan;120(1):127-41
Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.
Shen S, Kepp O, Martins I, Vitale I, Souquère S, Castedo M, Pierron G, Kroemer G
Cell cycle (Georgetown, Tex.) 2010 Jan 15;9(2):377-83
Cell cycle (Georgetown, Tex.) 2010 Jan 15;9(2):377-83
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition.
Tuffy LP, Concannon CG, D'Orsi B, King MA, Woods I, Huber HJ, Ward MW, Prehn JH
Molecular and cellular biology 2010 Dec;30(23):5484-501
Molecular and cellular biology 2010 Dec;30(23):5484-501
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation.
Gao C, Cao W, Bao L, Zuo W, Xie G, Cai T, Fu W, Zhang J, Wu W, Zhang X, Chen YG
Nature cell biology 2010 Aug;12(8):781-90
Nature cell biology 2010 Aug;12(8):781-90
Intracellular localization of GASP/ECOP/VOPP1.
Baras A, Moskaluk CA
Journal of molecular histology 2010 Apr;41(2-3):153-64
Journal of molecular histology 2010 Apr;41(2-3):153-64
The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras.
Byun JY, Yoon CH, An S, Park IC, Kang CM, Kim MJ, Lee SJ
Carcinogenesis 2009 Nov;30(11):1880-8
Carcinogenesis 2009 Nov;30(11):1880-8
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
