ABIN1449600
antibody from antibodies-online
Targeting: MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN1449600 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (cleaved) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Lung autophagic response following exposure of mice to whole body irradiation, with and without amifostine.
Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas.
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas.
Zois CE, Giatromanolaki A, Kainulainen H, Botaitis S, Torvinen S, Simopoulos C, Kortsaris A, Sivridis E, Koukourakis MI
Biochemical and biophysical research communications 2011 Jan 7;404(1):552-8
Biochemical and biophysical research communications 2011 Jan 7;404(1):552-8
Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas.
Giatromanolaki A, Koukourakis MI, Harris AL, Polychronidis A, Gatter KC, Sivridis E
Journal of clinical pathology 2010 Oct;63(10):867-72
Journal of clinical pathology 2010 Oct;63(10):867-72
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas.
Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL, Gatter KC, Giatromanolaki A
The American journal of pathology 2010 May;176(5):2477-89
The American journal of pathology 2010 May;176(5):2477-89
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Cleaved-LC3 Antibody (APG8a) Cat.-No AP32167PU-N in Mouse brain tissue lysate. Cleaved-LC3 (APG8a) was detected using the purified Pab.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- SY5Y cells were pretreated with 5nM bafilomycin for 24hr and fixed in 4% of paraformaldehyde. Treatment with Cleaved-LC3 Antibody (APG8a) Cat.-No AP32167PU-N at dilution 1/100. Data courtesy of Jianhui Zhu, MD, PhD & Charleen T. Chu, MD, PhD, University of Pittsburgh School of Medicine.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-Fixed, Paraffin-Embedded human cancer tissue reacted with the primary antibody Cleaved-LC3 Antibody (APG8a) Cat.-No AP32167PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.