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- References [19]
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- Product number
- 20371-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20371-1-AP, RRID:AB_10694153
- Product name
- SFRS2 antibody
- Antibody type
- Polyclonal
- Description
- SFRS2 antibody (Cat. #20371-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation.
5-Methylcytosine-modified circRNA-CCNL2 regulates vascular remdeling in hypoxic pulmonary hypertension through binding to FXR2.
5-azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia.
Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells.
Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation.
HuR promotes triglyceride synthesis and intestinal fat absorption.
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Perturb mRNA Splicing through Aberrant Interactions with SRSF2.
Chromatin target of protein arginine methyltransferases alleviates cerebral ischemia/reperfusion-induced injury by regulating RNA alternative splicing.
Neuronal activation affects the organization and protein composition of the nuclear speckles.
tRF-20-M0NK5Y93-induced MALAT1 promotes colon cancer metastasis through alternative splicing of SMC1A.
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
SRSF2 is required for mRNA splicing during spermatogenesis.
SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice.
SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.
Zhang N, Zhao R, Zhong X, Dong Q, Liu Y, Yu K, Han L, Meng F, Wu J, Chen Q, Li X, Chen Q, Zhang K, Huang H, Zhang J, Wu S, Ren Y, Wang W, Liu Y
Nature communications 2026 Jan 8;17(1):1406
Nature communications 2026 Jan 8;17(1):1406
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation.
Koo AS, Jia W, Kim S, Scalf M, Boos CE, Chen Y, Wang D, Voter AF, Bajaj A, Smith LM, Keck JL, Bakkenist CJ, Guo L, Tibbetts RS
bioRxiv : the preprint server for biology 2025 May 28;
bioRxiv : the preprint server for biology 2025 May 28;
5-Methylcytosine-modified circRNA-CCNL2 regulates vascular remdeling in hypoxic pulmonary hypertension through binding to FXR2.
Sun H, Liao X, Wang S, Yuan H, Bai J, Feng H, Li M, Song X, Ma C, Zhang L, Zhao X, Zheng X, Zhu D
International journal of biological macromolecules 2025 Mar;296:139638
International journal of biological macromolecules 2025 Mar;296:139638
5-azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia.
Gao B, Li Y, Zhao L, Zou Z, Ma X, Hong J, Xiang J, Dou X, Yang FC, Xu M, He C
bioRxiv : the preprint server for biology 2025 Jun 27;
bioRxiv : the preprint server for biology 2025 Jun 27;
Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells.
Lyu P, Agarwal G, Guo CJ, Ye T, Weng C, Antoszewski M, Joubran S, Caulier A, Poeschla M, Sankaran VG
bioRxiv : the preprint server for biology 2025 Jul 16;
bioRxiv : the preprint server for biology 2025 Jul 16;
Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.
Damodaran AP, Gavard O, Gagné JP, Rogalska ME, Behera AK, Mancini E, Bertolin G, Courtheoux T, Kumari B, Cailloce J, Mereau A, Poirier GG, Valcárcel J, Gonatopoulos-Pournatzis T, Watrin E, Prigent C
The Journal of biological chemistry 2025 Jan;301(1):108000
The Journal of biological chemistry 2025 Jan;301(1):108000
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation.
Koo AS, Jia W, Kim SH, Scalf M, Boos CE, Chen Y, Wang D, Voter AF, Bajaj A, Smith LM, Keck JL, Bakkenist CJ, Guo L, Tibbetts RS
The Journal of biological chemistry 2025 Dec;301(12):110857
The Journal of biological chemistry 2025 Dec;301(12):110857
HuR promotes triglyceride synthesis and intestinal fat absorption.
Liu C, Lin Y, Wang Y, Lin S, Zhou J, Tang H, Yi X, Ma Z, Xia T, Jiang B, Tian F, Ju Z, Liu B, Gu X, Yang Z, Wang W
Cell reports 2024 May 28;43(5):114238
Cell reports 2024 May 28;43(5):114238
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Perturb mRNA Splicing through Aberrant Interactions with SRSF2.
Chen X, Cao Z, Wang Y
Analytical chemistry 2024 Jun 11;96(23):9713-9720
Analytical chemistry 2024 Jun 11;96(23):9713-9720
Chromatin target of protein arginine methyltransferases alleviates cerebral ischemia/reperfusion-induced injury by regulating RNA alternative splicing.
Cui Y, Zhang Z, Lv M, Duan Z, Liu W, Gao J, Xu R, Wan Q
iScience 2024 Jan 19;27(1):108688
iScience 2024 Jan 19;27(1):108688
Neuronal activation affects the organization and protein composition of the nuclear speckles.
Szczepankiewicz AA, Parobczak K, Zaręba-Kozioł M, Ruszczycki B, Bijata M, Trzaskoma P, Hajnowski G, Holm-Kaczmarek D, Włodarczyk J, Sas-Nowosielska H, Wilczyński GM, Rędowicz MJ, Magalska A
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119829
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119829
tRF-20-M0NK5Y93-induced MALAT1 promotes colon cancer metastasis through alternative splicing of SMC1A.
Luan N, Wang J, Sheng B, Zhou Q, Ye X, Zhu X, Sun J, Tang Z, Wang J
American journal of cancer research 2023;13(3):852-871
American journal of cancer research 2023;13(3):852-871
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
Gu X, Li K, Zhang M, Chen Y, Zhou J, Yao C, Zang Y, He J, Wan J, Guo B
Cell reports 2023 Oct 31;42(10):113264
Cell reports 2023 Oct 31;42(10):113264
SRSF2 is required for mRNA splicing during spermatogenesis.
Lei WL, Du Z, Meng TG, Su R, Li YY, Liu W, Sun SM, Liu MY, Hou Y, Zhang CH, Gui Y, Schatten H, Han Z, Liu C, Sun F, Wang ZB, Qian WP, Sun QY
BMC biology 2023 Oct 23;21(1):231
BMC biology 2023 Oct 23;21(1):231
SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice.
Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22918
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22918
SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK
EMBO molecular medicine 2021 Nov 8;13(11):e14163
EMBO molecular medicine 2021 Nov 8;13(11):e14163
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6
Cell reports 2019 Jul 2;28(1):78-90.e6
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Raihan O, Brishti A, Molla MR, Li W, Zhang Q, Xu P, Khan MI, Zhang J, Liu Q
Neuroscience 2018 Oct 15;390:160-173
Neuroscience 2018 Oct 15;390:160-173
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.
Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L
Nature communications 2018 Jun 25;9(1):2464
Nature communications 2018 Jun 25;9(1):2464
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFRS2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SFRS2. This antibody recognizes human,mouse,rat antigen. The SFRS2 antibody has been validated for the following applications: ELISA, WB analysis.
