NB100-1774
antibody from Novus Biologicals
Targeting: SRSF2
PR264, SC-35, SC35, SFRS2, SFRS2A
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB100-1774 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1774, RRID:AB_10128431
- Product name
- Mouse Monoclonal SC35 Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. Recognizes a phospho-epitope on the non-snRNP (small nuclear ribonucleoprotein particles) factor SC-35. The antibody reacts with the splicing factor SC-35 and with the SC-35-related non-snRNP factor SF2/ASF.
- Reactivity
- Human, Mouse, Rat, Drosophila
- Host
- Mouse
- Antigen sequence
This antibody recognizes a phospho-
epitope of the non-snRNP (small nuc
lear ribonucleoprotein particles) f
actor SC35.- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation.
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.
Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2.
Gadd45a is an RNA binding protein and is localized in nuclear speckles.
A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys.
A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys.
Associations between distinct pre-mRNA splicing components and the cell nucleus.
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus.
Wu N, Nguyen XN, Wang L, Appourchaux R, Zhang C, Panthu B, Gruffat H, Journo C, Alais S, Qin J, Zhang N, Tartour K, Catez F, Mahieux R, Ohlmann T, Liu M, Du B, Cimarelli A
PLoS pathogens 2019 Oct;15(10):e1008093
PLoS pathogens 2019 Oct;15(10):e1008093
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.
Malik AM, Miguez RA, Li X, Ho YS, Feldman EL, Barmada SJ
eLife 2018 Jul 17;7
eLife 2018 Jul 17;7
Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2.
Grindheim AK, Hollås H, Raddum AM, Saraste J, Vedeler A
Journal of cell science 2016 Jan 15;129(2):314-28
Journal of cell science 2016 Jan 15;129(2):314-28
Gadd45a is an RNA binding protein and is localized in nuclear speckles.
Sytnikova YA, Kubarenko AV, Schäfer A, Weber AN, Niehrs C
PloS one 2011 Jan 7;6(1):e14500
PloS one 2011 Jan 7;6(1):e14500
A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys.
Nie GY, Hampton AL, Fu GQ, Liu YX, Findlay JK, Salamonsen LA
Reproduction (Cambridge, England) 2002 Aug;124(2):209-17
Reproduction (Cambridge, England) 2002 Aug;124(2):209-17
A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys.
Nie GY, Hampton AL, Fu GQ, Liu YX, Findlay JK, Salamonsen LA
Reproduction (Cambridge, England) 2002 Aug;124(2):209-17
Reproduction (Cambridge, England) 2002 Aug;124(2):209-17
Associations between distinct pre-mRNA splicing components and the cell nucleus.
Spector DL, Fu XD, Maniatis T
The EMBO journal 1991 Nov;10(11):3467-81
The EMBO journal 1991 Nov;10(11):3467-81
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus.
Fu XD, Maniatis T
Nature 1990 Feb 1;343(6257):437-41
Nature 1990 Feb 1;343(6257):437-41
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SC35 Antibody (SC-35) [NB100-1774] - SC-35 recombinant protein (3 ug) was separated on SDS-PAGE and probed with Mouse Anti-Splicing Factor SC-35 Clone: SC-35. The antibody was developed using Goat Anti-Mouse IgG-Peroxidase and a chemiluminescent substrate. Lanes 1. Antibody dilution 1:100; 2. Antibody dilution 1:250; 3. Antibody dilution 1:500; 4. Antibody dilution 1:1,000