Antibody data
- Antibody Data
- Antigen structure
- References [117]
- Comments [0]
- Validations [0]
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- Product number
- 10088-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10088-2-AP, RRID:AB_2062351
- Product name
- ATG7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG7 antibody (Cat. #10088-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Picornavirus VP3 protein induces autophagy through the TP53-BAD-BAX axis to promote viral replication.
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass decline.
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
ATG7/GAPLINC/IRF3 axis plays a critical role in regulating pathogenesis of influenza A virus.
Cellular evidence of communication strategies for small intestinal high endothelial cells: Ultrastructural insights of nano-scale exosomes and autophagy.
Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Progranulin Protects against Aspergillus fumigatus Keratitis by Attenuating the Inflammatory Response through Enhancing Autophagy.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
A new insight of cadmium-induced cellular evidence of autophagic-associated spermiophagy during spermatogenesis.
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy.
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress.
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Bushen Wenyang Huayu Decoction inhibits autophagy by regulating the SIRT1-FoXO-1 pathway in endometriosis rats.
Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model.
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K-Akt-mTOR pathway.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Low concentrations of tumor necrosis factor-alpha promote human periodontal ligament stem cells osteogenic differentiation by activation of autophagy via inhibition of AKT/mTOR pathway.
Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux.
Kartogenin Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Autophagy.
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
Upregulation of nuclear division cycle 80 contributes to therapeutic resistance via the promotion of autophagy-related protein-7-dependent autophagy in lung cancer.
Patient-driven discovery of CCN1 to rescue cutaneous wound healing in diabetes via the intracellular EIF3A/CCN1/ATG7 signaling by nanoparticle-enabled delivery.
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity.
The Role of Extracellular Vesicles in Optic Nerve Injury: Neuroprotection and Mitochondrial Homeostasis.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Nuclear Receptor 4A2 (NR4A2/NURR1) Regulates Autophagy and Chemoresistance in Pancreatic Ductal Adenocarcinoma.
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway.
Autophagy regulates functional differentiation of mammary epithelial cells.
Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes.
Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
JNK pathway and heat shock response mediate the survival of C26 colon carcinoma bearing mice fed with the mushroom Pleurotus eryngii var. eryngii without affecting tumor growth or cachexia.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
SIRT3 ameliorates osteoarthritis via regulating chondrocyte autophagy and apoptosis through the PI3K/Akt/mTOR pathway.
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis.
m(6)A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7.
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
STING directly activates autophagy to tune the innate immune response.
The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM(2.5)).
In Vivo Autophagy Up-Regulation of Small Intestine Enterocytes in Chinese Soft-Shelled Turtles during Hibernation.
Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury.
LIPOPHAGY: a novel form of steroidogenic activity within the LEYDIG cell during the reproductive cycle of turtle.
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Evaluating expression of autophagy-related genes in oriental river prawn Macrobrachium nipponense as potential biomarkers for hypoxia exposure.
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Fecal Microbiota Transplantation Beneficially Regulates Intestinal Mucosal Autophagy and Alleviates Gut Barrier Injury.
Preantral follicular atresia occurs mainly through autophagy, while antral follicles degenerate mostly through apoptosis.
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Water‑soluble nano‑pearl powder promotes MC3T3‑E1 cell differentiation by enhancing autophagy via the MEK/ERK signaling pathway.
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Increased expression of autophagy-related proteins in keratocystic odontogenic tumours: its possible association with growth potential.
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Mao R, Zhu Z, Yang F, Sun D, Zhou X, Cao W, Qin X, Dang W, Liu H, Tian H, Zhang K, Wu Q, Liu X, Zheng H
Autophagy 2024 Sep;20(9):1928-1947
Autophagy 2024 Sep;20(9):1928-1947
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Xu M, Zhong W, Yang C, Liu M, Yuan X, Lu T, Li D, Zhang G, Liu H, Zeng Y, Yang X, Zhou Y, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass decline.
Yu Y, Yang J, Zheng L, Su H, Cao S, Jiang X, Liu X, Liu W, Wang Z, Meng F, Xu H, Wen D, Sun C, Song X, Vidal-Puig A, Cao L
Molecular metabolism 2024 Mar;81:101892
Molecular metabolism 2024 Mar;81:101892
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Wu Z, Zhang W, Chen L, Wang T, Wang X, Shi H, Zhang L, Zhong M, Shi X, Mao X, Chen H, Li Q
Pharmacological research 2024 Mar;201:107097
Pharmacological research 2024 Mar;201:107097
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
Chen M, Zhang X, Kong F, Gao P, Ge X, Zhou L, Han J, Guo X, Zhang Y, Yang H
Autophagy 2024 Jun;20(6):1286-1313
Autophagy 2024 Jun;20(6):1286-1313
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Wu J, Jiang L, Wang S, Peng L, Zhang R, Liu Z
International immunopharmacology 2024 Jun 15;134:112235
International immunopharmacology 2024 Jun 15;134:112235
ATG7/GAPLINC/IRF3 axis plays a critical role in regulating pathogenesis of influenza A virus.
Chen B, Guo G, Wang G, Zhu Q, Wang L, Shi W, Wang S, Chen Y, Chi X, Wen F, Maarouf M, Huang S, Yang Z, Chen JL
PLoS pathogens 2024 Jan;20(1):e1011958
PLoS pathogens 2024 Jan;20(1):e1011958
Cellular evidence of communication strategies for small intestinal high endothelial cells: Ultrastructural insights of nano-scale exosomes and autophagy.
Hao P, Yin W, Chen X, Qin S, Yu Y, Yuan Y, Quan X, Hu B, Chen S, Wu Y
Micron (Oxford, England : 1993) 2024 Jan;176:103559
Micron (Oxford, England : 1993) 2024 Jan;176:103559
Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice.
Li X, Pan Y, Liu K, Yang Y, Ye Y, Xu Q, Fan M, Guo F
Cellular signalling 2024 Jan;113:110929
Cellular signalling 2024 Jan;113:110929
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.
Hou LS, Zhai XP, Zhang YW, Xing JH, Li C, Zhou SY, Zhu XH, Zhang BL
Liver international : official journal of the International Association for the Study of the Liver 2024 Aug;44(8):1937-1951
Liver international : official journal of the International Association for the Study of the Liver 2024 Aug;44(8):1937-1951
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Hu SS, Wang TY, Ni L, Hu FX, Yue BW, Zheng Y, Wang TL, Kumar A, Wang YY, Wang JE, Zhou ZY
Current medical science 2024 Aug;44(4):748-758
Current medical science 2024 Aug;44(4):748-758
Progranulin Protects against Aspergillus fumigatus Keratitis by Attenuating the Inflammatory Response through Enhancing Autophagy.
Qi P, Liu X, Li C, Xu Q, Hu L, Duan H, Zhao G, Lin J
ACS infectious diseases 2024 Aug 9;10(8):2826-2835
ACS infectious diseases 2024 Aug 9;10(8):2826-2835
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Zhang W, Chen L, Liu J, Chen B, Shi H, Chen H, Qi H, Wu Z, Mao X, Wang X, Huang Y, Li J, Yu Z, Zhong M, Wang T, Li Q
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
A new insight of cadmium-induced cellular evidence of autophagic-associated spermiophagy during spermatogenesis.
Ali W, Deng K, Sun J, Ma Y, Liu Z, Zou H
Environmental science and pollution research international 2023 Sep;30(45):101064-101074
Environmental science and pollution research international 2023 Sep;30(45):101064-101074
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Chen Q, Hu K, Shi J, Li H, Li W
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy.
Huang X, Yao J, Liu L, Chen J, Mei L, Huangfu J, Luo D, Wang X, Lin C, Chen X, Yang Y, Ouyang S, Wei F, Wang Z, Zhang S, Xiang T, Neculai D, Sun Q, Kong E, Tate EW, Yang A
Molecular cell 2023 Oct 5;83(19):3485-3501.e11
Molecular cell 2023 Oct 5;83(19):3485-3501.e11
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Lian N, Tong J, Zhu W, Meng Q, Jiang M, Bian M, Li Y
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
Li L, Li S, Pan Z, Zhang Y, Hua Z
Journal of neurochemistry 2023 Nov;167(4):582-599
Journal of neurochemistry 2023 Nov;167(4):582-599
ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress.
Liu J, Lu S, Zheng L, Guo Q, Cao L, Xiao Y, Chen D, Zou Y, Liu X, Deng C, Zhang S, Yang R, Wang Y, Zhang Y, Zhang N, Song X, Xing C, Wang Z, Cao L
Cell reports 2023 Nov 28;42(11):113402
Cell reports 2023 Nov 28;42(11):113402
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Liao D, Shangguan D, Wu Y, Chen Y, Liu N, Tang J, Yao D, Shi Y
Psychopharmacology 2023 May;240(5):1179-1190
Psychopharmacology 2023 May;240(5):1179-1190
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Shao D, Shen W, Miao Y, Gao Z, Pan M, Wei Q, Yan Z, Zhao X, Ma B
Journal of animal science and biotechnology 2023 May 3;14(1):61
Journal of animal science and biotechnology 2023 May 3;14(1):61
Bushen Wenyang Huayu Decoction inhibits autophagy by regulating the SIRT1-FoXO-1 pathway in endometriosis rats.
Li Y, An M, Fu X, Meng X, Ma Y, Liu H, Li Q, Xu H, Chen J
Journal of ethnopharmacology 2023 May 23;308:116277
Journal of ethnopharmacology 2023 May 23;308:116277
Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model.
Jiang X, Song Y, Fang J, Yang X, Mu S, Zhang J
International immunopharmacology 2023 Mar;116:109717
International immunopharmacology 2023 Mar;116:109717
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
Xing J, Hu C, Che S, Lan Y, Huang L, Liu L, Yin Y, Li H, Liao M, Qi W
Microbiology spectrum 2023 Jun 15;11(3):e0318622
Microbiology spectrum 2023 Jun 15;11(3):e0318622
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
Gou Q, Che S, Chen M, Chen H, Shi J, Hou Y
Cancer science 2023 Jul;114(7):2871-2881
Cancer science 2023 Jul;114(7):2871-2881
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Jia X, Qian J, Chen H, Liu Q, Hussain S, Jin J, Shi J, Hou Y
European journal of pharmacology 2023 Jul 5;950:175749
European journal of pharmacology 2023 Jul 5;950:175749
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Wu F, Tu C, Zhang K, Che H, Lin Q, Li Z, Zhou Q, Tang B, Yang Y, Chen M, Shao C
Biochemical and biophysical research communications 2023 Jan 15;640:173-182
Biochemical and biophysical research communications 2023 Jan 15;640:173-182
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K-Akt-mTOR pathway.
Chen H, Zhu T, Huang X, Xu W, Di Z, Ma Y, Xue M, Bi S, Shen Y, Yu Y, Shen Y, Feng L
Pharmacology research & perspectives 2023 Feb;11(1):e01041
Pharmacology research & perspectives 2023 Feb;11(1):e01041
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
Sun X, Du J, Meng H, Liu F, Yang N, Deng S, Wan H, Ye D, Song E, Zeng H
Cell biology and toxicology 2023 Dec;39(6):3255-3267
Cell biology and toxicology 2023 Dec;39(6):3255-3267
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Gou Q, Chen H, Chen M, Shi J, Jin J, Liu Q, Hou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Liu Y, Chen X, Zhao Y, Wang XY, Luo YW, Chen L, Wang W, Zhong S, Hu M, Dai Z, Jiang J, Wang X, Ji H, Cheng XX, Zheng A, Zuo J, Liu H, Ma D, Luo Z, Cao F, Hu S, Huang AL, Tang KF
Cell reports 2023 Aug 29;42(8):112852
Cell reports 2023 Aug 29;42(8):112852
Low concentrations of tumor necrosis factor-alpha promote human periodontal ligament stem cells osteogenic differentiation by activation of autophagy via inhibition of AKT/mTOR pathway.
Yuping Q, Yijun L, Limei W
Molecular biology reports 2023 Apr;50(4):3329-3339
Molecular biology reports 2023 Apr;50(4):3329-3339
Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux.
Saha K, Subramenium Ganapathy A, Wang A, Michael Morris N, Suchanec E, Ding W, Yochum G, Koltun W, Nighot M, Ma T, Nighot P
Journal of Crohn's & colitis 2023 Apr 3;17(3):433-449
Journal of Crohn's & colitis 2023 Apr 3;17(3):433-449
Kartogenin Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Autophagy.
Yan H, Yu T, Li J, Zhang T, Li Q, Zhou Y, Liu D
Stem cells international 2022;2022:1278921
Stem cells international 2022;2022:1278921
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
Zhou D, Yao Y, Zong L, Zhou G, Feng M, Chen J, Liu G, Chen G, Sun K, Yao H, Liu Y, Shi X, Zhang W, Shi B, Tai Q, Wu G, Sun L, Hu W, Zhu X, He S
International journal of biological sciences 2022;18(8):3374-3389
International journal of biological sciences 2022;18(8):3374-3389
Upregulation of nuclear division cycle 80 contributes to therapeutic resistance via the promotion of autophagy-related protein-7-dependent autophagy in lung cancer.
Chen X, He Q, Zeng S, Xu Z
Frontiers in pharmacology 2022;13:985601
Frontiers in pharmacology 2022;13:985601
Patient-driven discovery of CCN1 to rescue cutaneous wound healing in diabetes via the intracellular EIF3A/CCN1/ATG7 signaling by nanoparticle-enabled delivery.
Jiang JS, Zang J, Ru Y, Luo Y, Song JK, Luo Y, Fei XY, Zhang Z, Zhang Y, Yang D, Zhou M, Chen QL, Bai Y, Li YY, Kuai L, Li B
Biomaterials 2022 Sep;288:121698
Biomaterials 2022 Sep;288:121698
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Zhang S, Xie Y, Yan F, Zhang Y, Yang Z, Chen Z, Zhao Y, Huang Z, Cai L, Deng Z
Autophagy 2022 Sep;18(9):2229-2245
Autophagy 2022 Sep;18(9):2229-2245
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.
Ganapathy AS, Saha K, Suchanec E, Singh V, Verma A, Yochum G, Koltun W, Nighot M, Ma T, Nighot P
Autophagy 2022 Sep;18(9):2086-2103
Autophagy 2022 Sep;18(9):2086-2103
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Zhang W, Wu Z, Qi H, Chen L, Wang T, Mao X, Shi H, Chen H, Zhong M, Shi X, Wang X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
Hou W, Chen M, Ye C, Chen E, Li W, Zhang W
Biomolecules 2022 Oct 31;12(11)
Biomolecules 2022 Oct 31;12(11)
Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity.
Xiao Y, Wang J, Wang J, Wang H, Wu S, Bao W
Ecotoxicology and environmental safety 2022 Nov;246:114183
Ecotoxicology and environmental safety 2022 Nov;246:114183
The Role of Extracellular Vesicles in Optic Nerve Injury: Neuroprotection and Mitochondrial Homeostasis.
Park M, Shin HA, Duong VA, Lee H, Lew H
Cells 2022 Nov 22;11(23)
Cells 2022 Nov 22;11(23)
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
Liu J, Wang L, Ge L, Sun W, Song Z, Lu X, Jin C, Wu S, Yang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Wang C, Tang Z, Zhang Z, Liu T, Zhang J, Huang H, Li Y
Bioengineered 2022 Mar;13(3):7328-7339
Bioengineered 2022 Mar;13(3):7328-7339
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
He Z, Cai K, Zeng Z, Lei S, Cao W, Li X
Cell death & disease 2022 Mar 14;13(3):233
Cell death & disease 2022 Mar 14;13(3):233
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
Zhou J, Huang Q, Wang L, Li E, Huang W, Xiang Z
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2022 Jun;38(5):331-338
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2022 Jun;38(5):331-338
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Wang H, Zhou Y, Xu C, Cao Y, Xiao Y, Cai D, Uemoto Y, Wu S, Bao W
Chemosphere 2022 Jul;298:134199
Chemosphere 2022 Jul;298:134199
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
Zhou J, Tan Y, Hu L, Fu J, Li D, Chen J, Long Y
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.
Fan M, Gao J, Zhou L, Xue W, Wang Y, Chen J, Li W, Yu Y, Liu B, Shen Y, Xu Q
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4407-4423
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4407-4423
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
Shi L, Song Z, Li C, Deng F, Xia Y, Huang J, Wu X, Zhu J
Cells 2022 Dec 7;11(24)
Cells 2022 Dec 7;11(24)
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Zhou C, Dong X, Wang M, Qian X, Hu M, Liang K, Liang Y, Zhang R, Huang Y, Lyu H, Xiao S, Tang Y, Ali DW, Michalak M, Chen XZ, Tang J
Cell insight 2022 Aug;1(4):100045
Cell insight 2022 Aug;1(4):100045
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
Xia B, Zhong R, Wu W, Luo C, Meng Q, Gao Q, Zhao Y, Chen L, Zhang S, Zhao X, Zhang H
Microbiome 2022 Aug 31;10(1):139
Microbiome 2022 Aug 31;10(1):139
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420
Food & function 2022 Apr 20;13(8):4399-4420
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
Xie D, Zhao T, Zhang X, Kui L, Wang Q, Wu Y, Zheng T, Ma P, Zhang Y, Molteni H, Geng R, Yang Y, Li B, Zheng QY
Frontiers in cellular neuroscience 2021;15:753369
Frontiers in cellular neuroscience 2021;15:753369
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Liu Y, Zhong W, Zhang J, Chen W, Lu Y, Qiao Y, Zeng Z, Huang H, Cai S, Dong H
Frontiers in pharmacology 2021;12:739220
Frontiers in pharmacology 2021;12:739220
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Chen L, Niu X, Qiao X, Liu S, Ma H, Shi X, He X, Zhong M
Frontiers in immunology 2021;12:739039
Frontiers in immunology 2021;12:739039
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721
Experimental eye research 2021 Oct;211:108721
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Nuclear Receptor 4A2 (NR4A2/NURR1) Regulates Autophagy and Chemoresistance in Pancreatic Ductal Adenocarcinoma.
Zarei M, Shrestha R, Johnson S, Yu Z, Karki K, Vaziri-Gohar A, Epps J, Du H, Suva L, Zarei M, Safe S
Cancer research communications 2021 Nov;1(2):65-78
Cancer research communications 2021 Nov;1(2):65-78
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
Gao L, Yang X, Liang B, Jia Y, Tan S, Chen A, Cao P, Zhang Z, Zheng S, Sun L, Zhang F, Shao J
Toxicology 2021 Mar 30;452:152707
Toxicology 2021 Mar 30;452:152707
Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway.
Fan X, Zhou J, Yan X, Bi X, Liang J, Lu S, Luo L, Zhou D, Yin Z
Life sciences 2021 Jun 15;275:119355
Life sciences 2021 Jun 15;275:119355
Autophagy regulates functional differentiation of mammary epithelial cells.
Elswood J, Pearson SJ, Payne HR, Barhoumi R, Rijnkels M, W Porter W
Autophagy 2021 Feb;17(2):420-438
Autophagy 2021 Feb;17(2):420-438
Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes.
Xu T, Xu X, Chu Y, Jiang D, Xu G
International journal of molecular medicine 2021 Dec;48(6)
International journal of molecular medicine 2021 Dec;48(6)
Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling.
Chen F, Guo L, Di J, Li M, Dong D, Pei D
Journal of genetics and genomics = Yi chuan xue bao 2021 Dec;48(12):1091-1103
Journal of genetics and genomics = Yi chuan xue bao 2021 Dec;48(12):1091-1103
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
Wang Q, Liang D, Shen P, Yu Y, Yan Y, You W
Translational oncology 2021 Aug;14(8):101045
Translational oncology 2021 Aug;14(8):101045
JNK pathway and heat shock response mediate the survival of C26 colon carcinoma bearing mice fed with the mushroom Pleurotus eryngii var. eryngii without affecting tumor growth or cachexia.
Barone R, Caruso Bavisotto C, Rappa F, Gargano ML, Macaluso F, Paladino L, Vitale AM, Alfano S, Campanella C, Gorska M, Di Felice V, Cappello F, Venturella G, Marino Gammazza A
Food & function 2021 Apr 7;12(7):3083-3095
Food & function 2021 Apr 7;12(7):3083-3095
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
SIRT3 ameliorates osteoarthritis via regulating chondrocyte autophagy and apoptosis through the PI3K/Akt/mTOR pathway.
Xu K, He Y, Moqbel SAA, Zhou X, Wu L, Bao J
International journal of biological macromolecules 2021 Apr 1;175:351-360
International journal of biological macromolecules 2021 Apr 1;175:351-360
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, Zhao X, Yang L, Tao P, Xia P, Feng J
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
Yang Q, Li F, Miao Y, Luo X, Dai S, Liu J, Niu W, Sun Y
Journal of hazardous materials 2020 Nov 5;398:122327
Journal of hazardous materials 2020 Nov 5;398:122327
Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis.
Bao J, Chen Z, Xu L, Wu L, Xiong Y
Aging 2020 Mar 17;12(6):5152-5167
Aging 2020 Mar 17;12(6):5152-5167
m(6)A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7.
Wang X, Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, Shi H, Wang F, Wang Y
Autophagy 2020 Jul;16(7):1221-1235
Autophagy 2020 Jul;16(7):1221-1235
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
Xuan H, Ou A, Hao S, Shi J, Jin X
Nutrients 2020 Jan 29;12(2)
Nutrients 2020 Jan 29;12(2)
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Aras S, Purandare N, Gladyck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
STING directly activates autophagy to tune the innate immune response.
Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, Sehgal SA, Wang X, Wang J, Shang Y, Jiang Z, Liu L, Chen Q
Cell death and differentiation 2019 Sep;26(9):1735-1749
Cell death and differentiation 2019 Sep;26(9):1735-1749
The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM(2.5)).
Dai P, Shen D, Shen J, Tang Q, Xi M, Li Y, Li C
Chemosphere 2019 Nov;235:1134-1145
Chemosphere 2019 Nov;235:1134-1145
In Vivo Autophagy Up-Regulation of Small Intestine Enterocytes in Chinese Soft-Shelled Turtles during Hibernation.
Vistro WA, Zhang Y, Bai X, Yang P, Huang Y, Qu W, Baloch AS, Wu R, Tarique I, Chen Q
Biomolecules 2019 Nov 1;9(11)
Biomolecules 2019 Nov 1;9(11)
Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury.
Liu Z, Li T, Zhu F, Deng S, Li X, He Y
Cell death & disease 2019 Mar 7;10(3):227
Cell death & disease 2019 Mar 7;10(3):227
LIPOPHAGY: a novel form of steroidogenic activity within the LEYDIG cell during the reproductive cycle of turtle.
Tarique I, Vistro WA, Bai X, Yang P, Hong C, Huang Y, Haseeb A, Liu E, Gandahi NS, Xu M, Liu Y, Chen Q
Reproductive biology and endocrinology : RB&E 2019 Feb 9;17(1):19
Reproductive biology and endocrinology : RB&E 2019 Feb 9;17(1):19
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Tang B, Bao N, He G, Wang J
Gene 2019 Feb 20;686:56-62
Gene 2019 Feb 20;686:56-62
Evaluating expression of autophagy-related genes in oriental river prawn Macrobrachium nipponense as potential biomarkers for hypoxia exposure.
Sun S, Wu Y, Fu H, Yang M, Ge X, Zhu J, Xuan F, Wu X
Ecotoxicology and environmental safety 2019 Apr 30;171:484-492
Ecotoxicology and environmental safety 2019 Apr 30;171:484-492
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Ji L, Gao J, Kong R, Gao Y, Ji X, Zhao D
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Fecal Microbiota Transplantation Beneficially Regulates Intestinal Mucosal Autophagy and Alleviates Gut Barrier Injury.
Cheng S, Ma X, Geng S, Jiang X, Li Y, Hu L, Li J, Wang Y, Han X
mSystems 2018 Sep-Oct;3(5)
mSystems 2018 Sep-Oct;3(5)
Preantral follicular atresia occurs mainly through autophagy, while antral follicles degenerate mostly through apoptosis.
Meng L, Jan SZ, Hamer G, van Pelt AM, van der Stelt I, Keijer J, Teerds KJ
Biology of reproduction 2018 Oct 1;99(4):853-863
Biology of reproduction 2018 Oct 1;99(4):853-863
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Cui Y, Zhang Z, Zhang B, Zhao L, Hou C, Zeng Q, Nie J, Yu J, Zhao Y, Gao T, Wang A, Liu H
Toxicology letters 2018 Nov;297:24-33
Toxicology letters 2018 Nov;297:24-33
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, Song Z, Zhang L, Zhang X, Tian X
Neuropharmacology 2018 Jun;135:151-162
Neuropharmacology 2018 Jun;135:151-162
Water‑soluble nano‑pearl powder promotes MC3T3‑E1 cell differentiation by enhancing autophagy via the MEK/ERK signaling pathway.
Cheng Y, Zhang W, Fan H, Xu P
Molecular medicine reports 2018 Jul;18(1):993-1000
Molecular medicine reports 2018 Jul;18(1):993-1000
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Hu X, Mei S, Meng W, Xue S, Jiang L, Yang Y, Hui L, Chen Y, Guan MX
Cancer letters 2018 Jul 1;425:1-12
Cancer letters 2018 Jul 1;425:1-12
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Liu J, Lv X, Dong W, Hu M, Xu J, Qian G, Li Y
Inflammation 2018 Dec;41(6):2222-2235
Inflammation 2018 Dec;41(6):2222-2235
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
Pan S, Jia Y, Yang X, Cai D, Liu Z, Song H, Zhao R
European journal of nutrition 2018 Apr;57(3):991-1001
European journal of nutrition 2018 Apr;57(3):991-1001
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Chen S, Wu DD, Sang XB, Wang LL, Zong ZH, Sun KX, Liu BL, Zhao Y
Cell death & disease 2017 Oct 12;8(10):e3118
Cell death & disease 2017 Oct 12;8(10):e3118
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
Increased expression of autophagy-related proteins in keratocystic odontogenic tumours: its possible association with growth potential.
Li RF, Chen G, Zhao Y, Zhao YF, Liu B
The British journal of oral & maxillofacial surgery 2014 Jul;52(6):551-6
The British journal of oral & maxillofacial surgery 2014 Jul;52(6):551-6
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.
Jin R, Zhu W, Cao S, Chen R, Jin H, Liu Y, Wang S, Wang W, Xiao G
PloS one 2013;8(1):e52909
PloS one 2013;8(1):e52909
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Zhan Y, Gong K, Chen C, Wang H, Li W
Free radical biology & medicine 2012 Aug 1;53(3):532-43
Free radical biology & medicine 2012 Aug 1;53(3):532-43
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