67341-1-Ig

antibody from Proteintech Group

Targeting: ATG7 APG7L, DKFZp434N0735, GSA7

Provider product page for 67341-1-Ig

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Antibody data

Antibody Data
Antigen structure
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Product number: 67341-1-Ig - Provider product page
Provider: Proteintech Group
Product name: ATG7 antibody
Antibody type: Monoclonal
Description: KD/KO validated ATG7 antibody (Cat. #67341-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat, Pig and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 2B5A10
Vial size: 20ul, 150ul

ATG7 protein structure - 67341-1-Ig shown in red.

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Lin Z, Cheng Y, Tang Q, Zheng H, Li H, Lian Y
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NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells.

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Aging cell 2026 Feb;25(2):e70373

miR-512-3p/RPS6KA2 Axis Regulates Cisplatin Resistance in Ovarian Cancer via Autophagy and Ferroptosis.

Wu J, Chen H, Wang S, Peng L, Hu X, Liu Z
Oncology research 2025;34(1):26

Modular Nanoassemblies Mimicking p62 Aggregates for Targeted Organelle Sequestration and Degradation against Breast Cancer.

Li Y, Zhang Y, Wang J, Che Y, Gong T, Zhang Z, Liu R, Fu Y
ACS nano 2025 Oct 21;19(41):36478-36495

Dual-mechanism mucoadhesive hydrogel integrating pH-independent barriers and autophagy-driven immunotherapy for the treatment of ulcerative colitis.

Wang J, Ouyang S, Lin G, Li D, Ding B, Chen Y, Tong B, Ouyang T, Xu H, Wu W
Acta biomaterialia 2025 Oct 1;205:302-318

TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts.

Ly T, Pickard B, Pandey A, Yap M, Opara J, Arnold L, Martinez-Rivera N, Rosa-Molinar E, New J, Werner L, Farrokhian N, Gunewardena S, O'Neil M, Bur A, Anant S, Washburn MP, Barnaba C, Ding WX, Thomas SM
Autophagy 2025 Nov;21(11):2473-2496

Stress dynamically modulates neuronal autophagy to gate depression onset.

Yang L, Guo C, Zheng Z, Dong Y, Xie Q, Lv Z, Li M, Lu Y, Guo X, Deng R, Liu Y, Feng Y, Mu R, Zhang X, Ma H, Chen Z, Zhang Z, Dong Z, Yang W, Zhang X, Cui Y
Nature 2025 May;641(8062):427-437

A bacterial RING ubiquitin ligase triggering stepwise degradation of BRISC via TOLLIP-mediated selective autophagy manipulates host inflammatory response.

Pan X, Sun Y, Liu J, Chen R, Zhang Z, Li C, Yao H, Ma J
Autophagy 2025 Jun;21(6):1353-1372

METTL3 methylated KIF15 promotes nasopharyngeal carcinoma progression and radiation resistance by blocking ATG7-mediated autophagy through the activation of STAT3 pathway.

Li S, Wang S, Zhang L, Wu X, Tian L, Zou J, Pi G
Translational oncology 2025 Jan;51:102161

Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.

Zhang J, Fu Z, Wen F, Lyu P, Huang S, Cai X, Zhang Z, Zhang Y, Fan C, Man W, Sun X, Huang Y
Journal of neurophysiology 2025 Feb 1;133(2):490-501

RONIN/HCF1-TFEB Axis Protects Against D-Galactose-Induced Cochlear Hair Cell Senescence Through Autophagy Activation.

Wei Y, Zhang Y, Cao W, Cheng N, Xiao Y, Zhu Y, Xu Y, Zhang L, Guo L, Song J, Sha SH, Shao B, Ma F, Yang J, Ying Z, He Z, Chai R, Fang Q, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e2407880

Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis.

Ma L, Sun H, Xiang N, Xu Q
Scientific reports 2025 Apr 25;15(1):14516

Metallothionein 3 Potentiates Pulmonary Artery Smooth Muscle Cell Proliferation by Promoting Zinc-MTF1-ATG5 Axis-mediated Autophagosome Formation.

Xiong T, Li Y, Yang M, Huo B, Guo X, Liu L, Huang Y, Zhu X, Hu Q, Wei X, Jiang DS, Yi X
International journal of biological sciences 2024;20(8):2904-2921

LAMTOR1 decreased exosomal PD-L1 to enhance immunotherapy efficacy in non-small cell lung cancer.

Wu B, Huang X, Shi X, Jiang M, Liu H, Zhao L
Molecular cancer 2024 Sep 2;23(1):184

Mitochondrial tRNA(Glu) 14693A > G Mutation, an "Enhancer" to the Phenotypic Expression of Leber's Hereditary Optic Neuropathy.

Jin L, Gan D, He W, Wu N, Xiang S, Wei Y, Eriani G, Ji Y, Guan MX, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2401856

Saracatinib prompts hemin-induced K562 erythroid differentiation but suppresses erythropoiesis of hematopoietic stem cells.

Ding L, Chen D, Li Y, Xie Y, Sun X, Wang D
Human cell 2024 May;37(3):648-665

DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.

Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617

Inhibition of autophagy induced by tetrandrine promotes the accumulation of reactive oxygen species and sensitizes efficacy of tetrandrine in pancreatic cancer.

Wang Y, Xu T, Wang H, Xia G, Huang X
Cancer cell international 2024 Jul 10;24(1):241

Autophagy-enabled protein degradation: Key to platelet activation and ANGII production in patients with type 2 diabetes mellitus.

Wu Q, Yu S, Zang S, Peng K, Wang Z
Heliyon 2024 Aug 30;10(16):e36131

PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.

Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674

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Si X, Zhang G, Li M, Yao M, Shi X, Dong Z, Gao S
Pharmacology 2023;108(1):61-73

Enterovirus D68 capsid formation and stability requires acidic compartments.

Galitska G, Jassey A, Wagner MA, Pollack N, Miller K, Jackson WT
mBio 2023 Oct 31;14(5):e0214123

PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.

Kim KH, Oprescu SN, Snyder MM, Kim A, Jia Z, Yue F, Kuang S
Cell reports 2023 Nov 28;42(11):113329

TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.

Tang Q, Markby GR, MacNair AJ, Tang K, Tkacz M, Parys M, Phadwal K, MacRae VE, Corcoran BM
Cell proliferation 2023 Jun;56(6):e13435

DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.

Yu W, Ma L, Li X
Oncology reports 2023 Feb;49(2)

Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.

Zhu X, Guan Z, Fang Y, Zhang Y, Guan Z, Li S, Peng K
Journal of virology 2023 Apr 27;97(4):e0181422

Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.

Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515

Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.

Wang M, Liu K, Bu H, Cong H, Dong G, Xu N, Li C, Zhao Y, Jiang F, Zhang Y, Yuan B, Li R, Jiang J
Molecular therapy oncolytics 2022 Sep 15;26:314-329

Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.

Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970

Trillin inhibits myoblast differentiation via increasing autophagy.

Dai W, Liu K, Li R, Cao Y, Shen M, Tao J, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153962

Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.

Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen L, Hu H, Wang L
Molecular and cellular endocrinology 2022 May 1;547:111598

Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.

Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278

High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression.

Xue WJ, He CF, Zhou RY, Xu XD, Xiang LX, Wang JT, Wang XR, Zhou HG, Guo JC
Molecular brain 2022 Jul 18;15(1):61

Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells.

Pei T, Su G, Yang J, Gao W, Yang X, Zhang Y, Ren J, Shen Y, Liu X
International journal of molecular sciences 2022 Dec 11;23(24)

Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.

Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72

Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.

Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305

Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.

Zuo SQ, Li C, Liu YL, Tan YH, Wan X, Xu T, Li Q, Wang L, Wu YL, Deng FM, Tang B
FEBS open bio 2021 Oct;11(10):2705-2714

Nucleolar Stress Functions Upstream to Stimulate Expression of Autophagy Regulators.

Dannheisig DP, Schimansky A, Donow C, Pfister AS
Cancers 2021 Dec 10;13(24)

DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.

Cao Y, Li R, Shen M, Li C, Zou Y, Jiang Q, Liu S, Lu C, Li H, Liu H, Cai Y
Cell death & disease 2021 Apr 20;12(5):416

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.

Xu Q, Fan Y, Loor JJ, Liang Y, Sun X, Jia H, Zhao C, Xu C
Frontiers in pharmacology 2020;11:601716

SHANK3 Co-ordinately Regulates Autophagy and Apoptosis in Myocardial Infarction.

Man W, Gu J, Wang B, Zhang M, Hu J, Lin J, Sun D, Xiong Z, Gu X, Hao K, Guo B, Wei G, Zhang L, Song R, Li C, Wang H, Sun D
Frontiers in physiology 2020;11:1082

Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.

Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385

LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.

Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118

Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.

Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179

Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.

Inamura A, Muraoka-Hirayama S, Sakurai K
Biological & pharmaceutical bulletin 2019;42(12):1977-1987

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