Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 12222-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- DPEP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DPEP1 antibody (Cat. #12222-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis.
Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.
Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.
Li Y, Wang X, Zhang Q, Tian D, Bai Y, Feng Y, Liu W, Diao Z
International immunopharmacology 2024 May 30;133:111955
International immunopharmacology 2024 May 30;133:111955
Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.
Lau A, Rahn JJ, Chappellaz M, Chung H, Benediktsson H, Bihan D, von Mässenhausen A, Linkermann A, Jenne CN, Robbins SM, Senger DL, Lewis IA, Chun J, Muruve DA
Science advances 2022 Feb 4;8(5):eabm0142
Science advances 2022 Feb 4;8(5):eabm0142
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.
von Mässenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, Beer K, Hannani MT, Lau A, Peitzsch M, Hoppenz P, Locke S, Chavakis T, Kramann R, Muruve DA, Hugo C, Bornstein SR, Linkermann A
Science advances 2022 Feb 4;8(5):eabl8920
Science advances 2022 Feb 4;8(5):eabl8920
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Guan Y, Liang X, Ma Z, Hu H, Liu H, Miao Z, Linkermann A, Hellwege JN, Voight BF, Susztak K
Nature communications 2021 Aug 23;12(1):5078
Nature communications 2021 Aug 23;12(1):5078
Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.
Choudhury SR, Babes L, Rahn JJ, Ahn BY, Goring KR, King JC, Lau A, Petri B, Hao X, Chojnacki AK, Thanabalasuriar A, McAvoy EF, Tabariès S, Schraeder C, Patel KD, Siegel PM, Kopciuk KA, Schriemer DC, Muruve DA, Kelly MM, Yipp BG, Kubes P, Robbins SM, Senger DL
Cell 2019 Aug 22;178(5):1205-1221.e17
Cell 2019 Aug 22;178(5):1205-1221.e17
Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.
Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, Ulke-Lemée A, Beck PL, Benediktsson H, Jevnikar AM, Snelgrove SL, Hickey MJ, Senger DL, James MT, Macdonald JA, Kubes P, Jenne CN, Muruve DA
The Journal of clinical investigation 2018 Jul 2;128(7):2894-2913
The Journal of clinical investigation 2018 Jul 2;128(7):2894-2913
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DPEP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DPEP1. This antibody recognizes human,mouse,rat antigen. The DPEP1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
