Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8103 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- DPEP1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human DPEP1.
- Description
- DPEP1 (dipeptidase 1), also known as MDP, RDP or MBD1, is a 411 amino acid renal protein that localizes to the apical cell membrane and belongs to the peptidase M19 family. Existing as a disulfide-linked homodimer, DPEP1 uses zinc as a cofactor to catalyze the hydrolysis of various dipeptides and, via its catalytic activity, plays a role in glutathione and leukotriene metabolism. DPEP1 is functionally inhibited by L-penicillamine and is subject to post-translational N-glycosylation. The gene encoding DPEP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of DPEP1 polyclonal antibody