28454-1-AP

antibody from Proteintech Group

Targeting: SGK1 SGK

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

28454-1-AP

Provider

Proteintech Group

Product name

SGK1 antibody

Antibody type

Polyclonal

Description

SGK1 antibody (Cat. #28454-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

High-salt diet aggravates allergic rhinitis through the NFAT5 signaling pathway.

Jiang L, Wang Y, Huang J, Yao S, Yao Y, Zeb A, Raghavan V, Cheng L, Wang J
NPJ science of food 2026 Mar 3;10(1)

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SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.

Wang R, Wei M, Niu W, Chen J, Nan J, Zhang Y, Zhao X, Wang Q
Cells 2026 Mar 20;15(6)

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Non-canonical role of "S6K1-SGK1" pathway in neuronal necroptosis following traumatic brain injury.

Wang S, Tan Y, Hu M, Wang M, Liang L, Luo X, Chen D, Jiang B, Chen C, Huang J, Xiong K
Genes & diseases 2026 Jul;13(4):101876

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Mechanism of ultrasound-guided renal parenchymal injection of MSCs for the treatment of chronic kidney disease: down-regulated SGK1 promotes M2 macrophage polarization.

Wan S, Tang D, Yang Z, Zeng Y, Hu L, Zhu L, Xia C, Bao F, Ke C, Wang J
European journal of medical research 2026 Jan 6;31(1):211

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RFWD2 Mitigates AD-Like Cognitive Impairments via the JNK-SGK1 Signaling Pathway in Mice.

Ying M, Qi X, Wang A, Zhong G, Tong W, Yu D, Liu G, Guo Y
CNS neuroscience & therapeutics 2026 Apr;32(4):e70860

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LncRNA LINC01605 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection Through Regulating SGK1.

Li M, Li R, Zheng Z, Xiao C, Yang Q, Chen B, Dai X
Journal of cellular and molecular medicine 2025 Nov;29(22):e70963

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SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.

Yan Y, Peng J, He W, Chen Y, Ye W, Yin Z, Cao Y
Life sciences 2025 Nov 1;380:123939

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SGK1 mediates herpes simplex keratitis via the PI3K/SGK1/ Wnt signaling pathways.

Ye W, Tang S, Wang Y, Wang W, Liu Y, Xu H, Meng H, Lu Y, Huang Z, Ge Y
Cellular signalling 2025 Mar;127:111566

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Around-the-clock noise exposure induces hippocampus apoptosis and subsequent cognitive impairment via the PI3K/SGK1/Foxo3 signaling pathway.

Fu Y, Zheng P, She X, Zhu Y, Fu B, Ma K, Yang H, Gao X, Cui B
Journal of translational medicine 2025 Jun 2;23(1):613

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Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, inhibits adrenal aldosterone synthesis and renal ERK/EGR1 pathway in the treatment of diabetic kidney disease.

Saxu R, Tang H, Yu H, Ge H, Gu HF
Journal of ethnopharmacology 2025 Jun 12;349:119936

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Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.

Dong C, Zhou Y, Shen X, Hu S, Duan K, Chen T, Li W, Sun X, Li P, Wang P, Han Y, Li D, Zhi Q, Zhou J
Cell death & disease 2025 Jun 11;16(1):444

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Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice.

Wang C, Tang Y, Tang J, Zhang J, Wang S, Wu F, Wang S
European radiology experimental 2025 Jan 10;9(1):3

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Traditional Chinese Medicinal Leech Induces Apoptosis and Autophagy in Glioblastoma by SGK1/Caspase-3 and PI3K/AKT/mTOR Pathway.

Wu S, Zhou Y, Pei Z, Wang Y, Zhang Z
CNS neuroscience & therapeutics 2025 Dec;31(12):e70683

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Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.

Zhang E, Wang Y, Zhang H, Li X, Su Y, Cui J, Xu R, Mao X, Sang M, Lin Z, Zhou X
Free radical biology & medicine 2025 Aug 1;235:231-247

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Quercetin is a foe in the heart by targeting the hERG potassium channel.

Lu Z, Li S, Wei R, Li W, Huang Y, Yang T, Yan M
Iranian journal of basic medical sciences 2024;27(11):1397-1404

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Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12.

Zhang X, Zhang Z, Zhao Y, Jin L, Tai Y, Tang Y, Geng S, Zhang H, Zhai Y, Yang Y, Pan P, He P, Fang S, Sun C, Chen Y, Zhou M, Liu L, Wang H, Xu L, Zhang T, Hua J, Wang H, Zhang L
International journal of biological sciences 2024;20(8):2922-2942

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CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.

Wang D, Li Y, Chang W, Feng M, Yang Y, Zhu X, Liu Z, Fu Y
Cell death & disease 2024 Sep 27;15(9):693

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Modeling of senescence-related chemoresistance in ovarian cancer using data analysis and patient-derived organoids.

Cai X, Li Y, Zheng J, Liu L, Jiao Z, Lin J, Jiang S, Lin X, Sun Y
Frontiers in oncology 2023;13:1291559

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SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity.

Han X, Ren J, Lohner H, Yakoumatos L, Liang R, Wang H
The Journal of biological chemistry 2022 Jun;298(6):102036

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PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.

Chen Q, Jin J, Guo W, Tang Z, Luo Y, Ying Y, Lin H, Luo Z
International journal of molecular sciences 2022 Aug 8;23(15)