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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [1]
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- Product number
- sc-7220 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-7220, RRID:AB_2287961
- Product name
- Anti-TRAF5
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Rabbit
Submitted references The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.
He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, Shan M, Xiong H, Bussel JB, Chiu A, Puel A, Reichenbach J, Marodi L, Döffinger R, Vasconcelos J, Issekutz A, Krause J, Davies G, Li X, Grimbacher B, Plebani A, Meffre E, Picard C, Cunningham-Rundles C, Casanova JL, Cerutti A
Nature immunology 2010 Sep;11(9):836-45
Nature immunology 2010 Sep;11(9):836-45
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.
Hauer J, Püschner S, Ramakrishnan P, Simon U, Bongers M, Federle C, Engelmann H
Proceedings of the National Academy of Sciences of the United States of America 2005 Feb 22;102(8):2874-9
Proceedings of the National Academy of Sciences of the United States of America 2005 Feb 22;102(8):2874-9
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.
- Validation comment
- Staining pattern partly consistent with experimental and/or bioinformatic data.
