Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12868-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12868-1-AP, RRID:AB_2209712
- Product name
- TRAF5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRAF5 antibody (Cat. #12868-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references IL-17 promotes melanoma through TRAF2 as a scaffold protein recruiting PIAS2 and ELAVL1 to induce EPHA5.
Integrated analysis identifies low microRNA-215 expression as associated with a poor prognosis of patients with colorectal cancer through the IKβ-α signaling pathway.
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
TRAF5 protects against myocardial ischemia reperfusion injury via AKT signaling.
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Du J, Du Y, Chen L, Liu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547
Integrated analysis identifies low microRNA-215 expression as associated with a poor prognosis of patients with colorectal cancer through the IKβ-α signaling pathway.
Wang Z, Jiang X, Li Q, Jin Y, Liu X, Wang F, Mao Y, Hua D
Translational cancer research 2020 Sep;9(9):5233-5244
Translational cancer research 2020 Sep;9(9):5233-5244
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Ma Y, Duan J, Hao X
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
TRAF5 protects against myocardial ischemia reperfusion injury via AKT signaling.
Xu W, Zhang L, Ma S, Zhang Y, Cai Z, Zhang K, Jin D
European journal of pharmacology 2020 Jul 5;878:173092
European journal of pharmacology 2020 Jul 5;878:173092
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
Peng P, Chen T, Wang Q, Zhang Y, Zheng F, Huang S, Tang Y, Yang C, Ding W, Ren D, Huang Z, Guo Y
Oncology research and treatment 2019;42(4):165-185
Oncology research and treatment 2019;42(4):165-185
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
Wang H, Ouyang L, Gao S
Translational cancer research 2019 Aug;8(4):1578-1590
Translational cancer research 2019 Aug;8(4):1578-1590
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
Wang B, Zhao H, Zhao L, Zhang Y, Wan Q, Shen Y, Bu X, Wan M, Shen C
Cancer letters 2017 Nov 1;408:60-70
Cancer letters 2017 Nov 1;408:60-70
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12868-1-AP(TRAF5 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRAF5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRAF5. This antibody recognizes human, mouse, rat antigen. The TRAF5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.