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- References [14]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12140-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12140-1-AP, RRID:AB_10666284
- Product name
- NCKAP1 antibody
- Antibody type
- Polyclonal
- Description
- NCKAP1 antibody (Cat. #12140-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy.
Based on disulfide accumulation, leveraging a THBS1-signature to improve the outcome of head and neck carcinoma patients.
A Novel Disulfidptosis-Related Diagnostic Gene Signature and Differential Expression Validation in Ischaemic Cardiomyopathy.
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma.
The WAVE complex drives the morphogenesis of the photoreceptor outer segment cilium.
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria.
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma.
Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.
Selenoprotein S is involved in maintenance and transport of multiprotein complexes.
Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.
Bo X, Fan J, Xu S, Zeng Y, Xu A, Wang X, Wang H, Kang P, Fu Y, Fan H, Tan X, Zhou Y
Journal of inflammation research 2025;18:9967-9988
Journal of inflammation research 2025;18:9967-9988
Based on disulfide accumulation, leveraging a THBS1-signature to improve the outcome of head and neck carcinoma patients.
Jin Y, Wang Z, Zhou C, Wen M, Zhou Y, Huang S
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147679
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147679
A Novel Disulfidptosis-Related Diagnostic Gene Signature and Differential Expression Validation in Ischaemic Cardiomyopathy.
Tan X, Xu S, Zeng Y, Yu F, Qin Z, Zhang G, Fan J, Bo X, Tang J, Fan H, Zhou Y
Journal of cellular and molecular medicine 2025 Mar;29(5):e70475
Journal of cellular and molecular medicine 2025 Mar;29(5):e70475
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Zhao L, Zhang J, Song Q, Dai C, Qin Y, Li A
Frontiers in cell and developmental biology 2024;12:1516898
Frontiers in cell and developmental biology 2024;12:1516898
Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma.
Zhang Y, Sun J, Li M, Hou L, Wang Z, Dong H, Xu W, Jiang R, Geng Y, Guan C, Zhu Z, Wang H, Gong Q, Zhang G
Heliyon 2024 Jan 15;10(1):e23502
Heliyon 2024 Jan 15;10(1):e23502
The WAVE complex drives the morphogenesis of the photoreceptor outer segment cilium.
Spencer WJ, Schneider NF, Lewis TR, Castillo CM, Skiba NP, Arshavsky VY
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 21;120(12):e2215011120
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 21;120(12):e2215011120
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Chen J, Ge J, Zhang W, Xie X, Zhong X, Tang S
Frontiers in genetics 2022;13:764957
Frontiers in genetics 2022;13:764957
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria.
Fung TS, Chakrabarti R, Kollasser J, Rottner K, Stradal TEB, Kage F, Higgs HN
Current biology : CB 2022 Apr 11;32(7):1577-1592.e8
Current biology : CB 2022 Apr 11;32(7):1577-1592.e8
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
Li K, Peng YF, Guo JZ, Li M, Zhang Y, Chen JY, Lin TR, Yu X, Yu WD
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma.
Zhong XP, Kan A, Ling YH, Lu LH, Mei J, Wei W, Li SH, Guo RP
Cell death & disease 2019 May 8;10(5):369
Cell death & disease 2019 May 8;10(5):369
Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
Gromnitza S, Lepa C, Weide T, Schwab A, Pavenstädt H, George B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Mar;32(3):1665-1676
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Mar;32(3):1665-1676
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.
Wilkinson B, Li J, Coba MP
Scientific reports 2017 Jul 13;7(1):5272
Scientific reports 2017 Jul 13;7(1):5272
Selenoprotein S is involved in maintenance and transport of multiprotein complexes.
Turanov AA, Shchedrina VA, Everley RA, Lobanov AV, Yim SH, Marino SM, Gygi SP, Hatfield DL, Gladyshev VN
The Biochemical journal 2014 Sep 15;462(3):555-65
The Biochemical journal 2014 Sep 15;462(3):555-65
Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.
Wu S, Ma L, Wu Y, Zeng R, Zhu X
Cell research 2012 Aug;22(8):1270-84
Cell research 2012 Aug;22(8):1270-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12140-1-AP(NAP1;NCKAP1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NCKAP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NCKAP1. This antibody recognizes human,mouse,rat antigen. The NCKAP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
