BS6822

antibody from Bioworld Technology, Inc
Targeting: CCN1 CYR61, GIG1, IGFBP10
Provider product page for BS6822
Western blot
Immunohistochemistry

Antibody data

Product number
BS6822 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CYR61 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CYR61.
Description
Cyr61 is a secreted heparin binding protein, encoded by a growth factor-inducible immediate-early gene, that associates with the extracellular matrix and connective tissue. Cyr61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse Cyr61 homolog, Fisp12. As an angiogenic inducer, Cyr61 binds to the cell surface receptor Integrin aV/b3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of Cyr61 is elevated during vessel growth, wound healing and chondrocyte differentiation. Cyr61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CCN1 protein structure - BS6822 shown in red.