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- Antigen structure
- References [32]
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- Product number
- 26689-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CYR61/CCN1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CYR61/CCN1 antibody (Cat. #26689-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 Pathway.
YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Modulation of the hippo-YAP pathway by cyclic stretch in rat type 2 alveolar epithelial cells-a proof-of-concept study.
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
CCN1 secreted by human adipose-derived stem cells enhances wound healing and promotes angiogenesis through activating the AKT signalling pathway.
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity.
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
Patient-driven discovery of CCN1 to rescue cutaneous wound healing in diabetes via the intracellular EIF3A/CCN1/ATG7 signaling by nanoparticle-enabled delivery.
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Diabetes Promotes Retinal Vascular Endothelial Cell Injury by Inducing CCN1 Expression.
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.
A translational program that suppresses metabolism to shield the genome.
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma.
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes.
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
A Novel Electrochemiluminescent Immunoassay Based on Target Transformation Assisted with Catalyzed Hairpin Assembly Amplification for the Ultrasensitive Bioassay.
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress.
Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion.
EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy.
Expression of YAP/TAZ in Keratocystic Odontogenic Tumors and Its Possible Association with Proliferative Behavior.
Hu K, Xie L, Wu W, Zhang J, Li Y, He J, Zhang Y, Lu D, Koeffler HP, Lin L, Yin D
International journal of biological sciences 2024;20(8):3140-3155
International journal of biological sciences 2024;20(8):3140-3155
YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.
Li X, Zhong H, Shi Q, Ruan R, Huang C, Wen Q, Zeng S, Xia Y, Zeng Q, Xiong J, Wang S, Chen J, Lei W, Deng J
Cellular and molecular life sciences : CMLS 2024 Mar 17;81(1):143
Cellular and molecular life sciences : CMLS 2024 Mar 17;81(1):143
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
Chen H, Shang Y, Li X, Wang R
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Li X, Xie Z, Zhou Q, Tan X, Meng W, Pang Y, Huang L, Ding Z, Hu Y, Li R, Huang G, Li H
Molecular neurobiology 2024 Feb;61(2):1175-1186
Molecular neurobiology 2024 Feb;61(2):1175-1186
Modulation of the hippo-YAP pathway by cyclic stretch in rat type 2 alveolar epithelial cells-a proof-of-concept study.
Ran X, Müller S, Brunssen C, Huhle R, Scharffenberg M, Schnabel C, Koch T, Gama de Abreu M, Morawietz H, Ferreira JMC, Wittenstein J
Frontiers in physiology 2023;14:1253810
Frontiers in physiology 2023;14:1253810
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Guo Y, Cui Y, Li Y, Jin X, Wang D, Lei M, Chen F, Liu Y, Xu J, Yao G, Zeng G, Chen X
Cancer communications (London, England) 2023 May;43(5):582-612
Cancer communications (London, England) 2023 May;43(5):582-612
CCN1 secreted by human adipose-derived stem cells enhances wound healing and promotes angiogenesis through activating the AKT signalling pathway.
Yang Y, Li S, Sun X, Zhang L, Chen M, Fu H
International wound journal 2023 May;20(5):1667-1677
International wound journal 2023 May;20(5):1667-1677
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
Chen BJ, Jiang J, Li T, Jiang HJ, Liang XH, Tang YL
Biochemical and biophysical research communications 2023 May 7;655:127-137
Biochemical and biophysical research communications 2023 May 7;655:127-137
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity.
Pusec CM, Ilievski V, De Jesus A, Farooq Z, Zapater JL, Sweis N, Ismail H, Khan MW, Ardehali H, Cordoba-Chacon J, Layden BT
Scientific reports 2023 May 17;13(1):8034
Scientific reports 2023 May 17;13(1):8034
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
Sun Y, Jin X, Meng J, Guo F, Chen T, Zhao X, Wu H, Ren D
The EMBO journal 2023 Dec 1;42(23):e114558
The EMBO journal 2023 Dec 1;42(23):e114558
CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
Chen S, Xu Y, Yang B
Functional & integrative genomics 2023 Aug 8;23(3):270
Functional & integrative genomics 2023 Aug 8;23(3):270
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
Yuan P, Feng Z, Huang H, Wang G, Chen Z, Xu G, Xie Z, Jie Z, Zhao X, Ma Q, Wang S, Shen Y, Huang Y, Han Y, Ye H, Wang J, Shi P, Sun X
International journal of biological sciences 2022;18(8):3122-3136
International journal of biological sciences 2022;18(8):3122-3136
Patient-driven discovery of CCN1 to rescue cutaneous wound healing in diabetes via the intracellular EIF3A/CCN1/ATG7 signaling by nanoparticle-enabled delivery.
Jiang JS, Zang J, Ru Y, Luo Y, Song JK, Luo Y, Fei XY, Zhang Z, Zhang Y, Yang D, Zhou M, Chen QL, Bai Y, Li YY, Kuai L, Li B
Biomaterials 2022 Sep;288:121698
Biomaterials 2022 Sep;288:121698
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Shi H, Zhang Y, Wang Y, Fang P, Liu Y, Li W
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Toxicology and applied pharmacology 2022 Mar 15;439:115926
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Ferrand N, Fert A, Morichon R, Radosevic-Robin N, Zaoui M, Sabbah M
Cancers 2022 Mar 14;14(6)
Cancers 2022 Mar 14;14(6)
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Terry BK, Park R, Cho SH, Crino PB, Kim S
Human molecular genetics 2022 Jun 22;31(12):1979-1996
Human molecular genetics 2022 Jun 22;31(12):1979-1996
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Huang Y, Zou Y, Jie Z
Experimental and therapeutic medicine 2022 Feb;23(2):118
Experimental and therapeutic medicine 2022 Feb;23(2):118
Diabetes Promotes Retinal Vascular Endothelial Cell Injury by Inducing CCN1 Expression.
Li H, Li T, Wang H, He X, Li Y, Wen S, Peng R, Nie Y, Lu Y, Yang H, Ye Y, Shi G, Chen Y
Frontiers in cardiovascular medicine 2021;8:689318
Frontiers in cardiovascular medicine 2021;8:689318
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Fang P, Deng WJ, Fan N, Shi J, Shi HY, Ou L, Pan JL, Yang SY
Environmental toxicology 2021 Nov;36(11):2225-2235
Environmental toxicology 2021 Nov;36(11):2225-2235
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Xu G, Seng Z, Zhang M, Qu J
Environmental toxicology 2021 Dec;36(12):2500-2511
Environmental toxicology 2021 Dec;36(12):2500-2511
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.
Yan F, Wang Q, Xia M, Ru Y, Hu W, Yan G, Xiong X, Zhang M, Wang J, Li Q, Zhang B, Wang H, Lin W, Wu G, Li X
Cancer biology & medicine 2021 Dec 22;19(6):818-35
Cancer biology & medicine 2021 Dec 22;19(6):818-35
A translational program that suppresses metabolism to shield the genome.
Balukoff NC, Ho JJD, Theodoridis PR, Wang M, Bokros M, Llanio LM, Krieger JR, Schatz JH, Lee S
Nature communications 2020 Nov 13;11(1):5755
Nature communications 2020 Nov 13;11(1):5755
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma.
Miao X, Zhang N
Experimental and molecular pathology 2020 Dec;117:104546
Experimental and molecular pathology 2020 Dec;117:104546
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes.
Sun J, Zhang W, Tan Z, Zheng C, Tang Y, Ke X, Zhang Y, Liu Y, Li P, Hu Q, Wang H, Mao P, Zheng Z
Virulence 2020 Dec;11(1):113-131
Virulence 2020 Dec;11(1):113-131
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K
OncoTargets and therapy 2019;12:869-882
OncoTargets and therapy 2019;12:869-882
A Novel Electrochemiluminescent Immunoassay Based on Target Transformation Assisted with Catalyzed Hairpin Assembly Amplification for the Ultrasensitive Bioassay.
Lei HX, Niu CC, Li T, Wan YF, Liang WB, Yuan R, Liao P
ACS applied materials & interfaces 2019 Aug 28;11(34):31427-31433
ACS applied materials & interfaces 2019 Aug 28;11(34):31427-31433
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Li M, Chen J, Yu X, Xu S, Li D, Zheng Q, Yin Y
Cells 2019 Apr 17;8(4)
Cells 2019 Apr 17;8(4)
Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress.
Gao M, Chen M, Li C, Xu M, Liu Y, Cong M, Sang N, Liu S
Cell discovery 2018;4:5
Cell discovery 2018;4:5
Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion.
Wang H, Shao X, He Q, Wang C, Xia L, Yue D, Qin G, Jia C, Chen R
Journal of proteome research 2018 Oct 5;17(10):3360-3369
Journal of proteome research 2018 Oct 5;17(10):3360-3369
EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy.
Xia H, Dai X, Yu H, Zhou S, Fan Z, Wei G, Tang Q, Gong Q, Bi F
Cell death & disease 2018 Feb 15;9(3):269
Cell death & disease 2018 Feb 15;9(3):269
Expression of YAP/TAZ in Keratocystic Odontogenic Tumors and Its Possible Association with Proliferative Behavior.
Man QW, Ma YQ, Liu JY, Zhao Y, Liu B, Zhao YF
BioMed research international 2017;2017:4624890
BioMed research international 2017;2017:4624890
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