10188-1-AP
antibody from Proteintech Group
Targeting: TGFBI
BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1
Antibody data
- Antibody Data
- Antigen structure
- References [68]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [4]
Submit
Validation data
Reference
Comment
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- Product number
- 10188-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10188-1-AP, RRID:AB_2202311
- Product name
- TGFBI / BIGH3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TGFBI / BIGH3 antibody (Cat. #10188-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cancer-associated fibroblast spatial heterogeneity and EMILIN1 expression in the tumor microenvironment modulate TGF-β activity and CD8(+) T-cell infiltration in breast cancer.
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
HIF-2α-dependent TGFBI promotes ovarian cancer chemoresistance by activating PI3K/Akt pathway to inhibit apoptosis and facilitate DNA repair process.
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
An engineered glioblastoma model yields novel macrophage-secreted drivers of invasion.
OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis.
Comprehensive isolation of extracellular vesicles and nanoparticles.
Investigating the Role of TGF-β Signaling Pathways in Human Corneal Endothelial Cell Primary Culture.
Significance of Lipopolysaccharides in Gastric Cancer and Their Potential as a Biomarker for Nivolumab Sensitivity.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.
Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.
Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506.
Dihydropyrimidinase Like 2 Promotes Bladder Cancer Progression via Pyruvate Kinase M2-Induced Aerobic Glycolysis and Epithelial-Mesenchymal Transition.
High Serpin Family A Member 10 Expression Confers Platinum Sensitivity and Is Associated With Survival Benefit in High-Grade Serous Ovarian Cancer: Based on Quantitative Proteomic Analysis.
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
MiR-21-5p Induces Pyroptosis in Colorectal Cancer via TGFBI.
Raloxifene and n-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa.
High Stromal TGFBI in Lung Cancer and Intratumoral CD8-Positive T Cells were Associated with Poor Prognosis and Therapeutic Resistance to Immune Checkpoint Inhibitors.
Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia.
Dual peptide-dendrimer conjugate inhibits acetylation of transforming growth factor β-induced protein and improves survival in sepsis.
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C.
Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer.
Secreted TGF-beta-induced protein promotes aggressive progression in bladder cancer cells.
TGFBI Promotes Tumor Growth and is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma.
PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia.
TGFBI Protein Is Increased in the Urine of Patients with High-Grade Urothelial Carcinomas, and Promotes Cell Proliferation and Migration.
Collagen fiber changes related to keratoconus with secondary corneal amyloidosis.
High stromal transforming growth factor β-induced expression is a novel marker of progression and poor prognosis in gastric cancer.
Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line.
c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer.
BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation.
Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury.
Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer.
Clinical implications of transforming growth factor-beta-induced gene-h3 protein expression in lung cancer.
New histopathologic and ultrastructural findings in Reis-Bücklers corneal dystrophy caused by the Arg124Leu mutation of TGFBI gene.
Comparative proteomic analysis of extracellular secreted proteins expressed by two pathogenic Acanthamoeba castellanii clinical isolates and a non-pathogenic ATCC strain.
TGFBI Expression in Cancer Stromal Cells is Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma.
Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia.
Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2.
ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells.
Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury.
Tgfbi/Bigh3 silencing activates ERK in mouse retina.
The role of TGFBI (βig-H3) in gastrointestinal tract tumorigenesis.
Identification and validation of TGFBI as a promising prognosis marker of clear cell renal cell carcinoma.
Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues.
TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients.
TGF-β-induced (TGFBI) protein in melanoma: a signature of high metastatic potential.
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.
Ginseng treatment attenuates chronic cyclosporine nephropathy via reducing oxidative stress in an experimental mouse model.
Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model.
Construction of eukaryotic plasmid expressing human TGFBI and its influence on human corneal epithelial cells.
A unique TGFBI protein in granular corneal dystrophy types 1 and 2.
Matrix metalloproteinase 9 (MMP-9)-dependent processing of βig-h3 protein regulates cell migration, invasion, and adhesion.
Role of leukotriene B₄ receptor signaling in human preadipocyte differentiation.
Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells.
Unique TGFBI protein in lattice corneal dystrophy.
Analysis of the human pancreatic stellate cell secreted proteome.
Novel CHST6 gene mutations in 2 unrelated cases of macular corneal dystrophy.
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
TGFBI expression is associated with a better response to chemotherapy in NSCLC.
Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma.
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer.
Honda CK, Kurozumi S, Fujii T, Pourquier D, Khellaf L, Boissiere F, Horiguchi J, Oyama T, Shirabe K, Colinge J, Yokobori T, Turtoi A
Theranostics 2024;14(5):1873-1885
Theranostics 2024;14(5):1873-1885
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
Tang S, Zhang J, Lou F, Zhou H, Cai X, Wang Z, Sun L, Sun Y, Li X, Fan L, Li Y, Jin X, Deng S, Yin Q, Bai J, Wang H, Wang H
EMBO reports 2024 Mar;25(3):1208-1232
EMBO reports 2024 Mar;25(3):1208-1232
HIF-2α-dependent TGFBI promotes ovarian cancer chemoresistance by activating PI3K/Akt pathway to inhibit apoptosis and facilitate DNA repair process.
Ma S, Wang J, Cui Z, Yang X, Cui X, Li X, Zhao L
Scientific reports 2024 Feb 16;14(1):3870
Scientific reports 2024 Feb 16;14(1):3870
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Świerczewska M, Sterzyńska K, Ruciński M, Andrzejewska M, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
An engineered glioblastoma model yields novel macrophage-secreted drivers of invasion.
Akins EA, Wilkins D, Aghi MK, Kumar S
bioRxiv : the preprint server for biology 2023 Nov 19;
bioRxiv : the preprint server for biology 2023 Nov 19;
OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis.
Li M, Wang X, Yang E, Li Y, Geng Y, Chen Z, Huang S, Zhang D, Wu H
Arteriosclerosis, thrombosis, and vascular biology 2023 May;43(5):654-673
Arteriosclerosis, thrombosis, and vascular biology 2023 May;43(5):654-673
Comprehensive isolation of extracellular vesicles and nanoparticles.
Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Coffey RJ
Nature protocols 2023 May;18(5):1462-1487
Nature protocols 2023 May;18(5):1462-1487
Investigating the Role of TGF-β Signaling Pathways in Human Corneal Endothelial Cell Primary Culture.
Aouimeur I, Sagnial T, Coulomb L, Maurin C, Thomas J, Forestier P, Ninotta S, Perrache C, Forest F, Gain P, Thuret G, He Z
Cells 2023 Jun 14;12(12)
Cells 2023 Jun 14;12(12)
Significance of Lipopolysaccharides in Gastric Cancer and Their Potential as a Biomarker for Nivolumab Sensitivity.
Nakazawa N, Yokobori T, Sohda M, Hosoi N, Watanabe T, Shimoda Y, Ide M, Sano A, Sakai M, Erkhem-Ochir B, Ogawa H, Shirabe K, Saeki H
International journal of molecular sciences 2023 Jul 22;24(14)
International journal of molecular sciences 2023 Jul 22;24(14)
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.
Liu X, Li N, Zhang C, Wu X, Zhang S, Dong G, Liu G
Translational oncology 2022 May;19:101389
Translational oncology 2022 May;19:101389
Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.
Ouni E, Nedbal V, Da Pian M, Cao H, Haas KT, Peaucelle A, Van Kerk O, Herinckx G, Marbaix E, Dolmans MM, Tuuri T, Otala M, Amorim CA, Vertommen D
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:91-120
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:91-120
Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506.
Jahr H, van der Windt AE, Timur UT, Baart EB, Lian WS, Rolauffs B, Wang FS, Pufe T
International journal of molecular sciences 2022 May 4;23(9)
International journal of molecular sciences 2022 May 4;23(9)
Dihydropyrimidinase Like 2 Promotes Bladder Cancer Progression via Pyruvate Kinase M2-Induced Aerobic Glycolysis and Epithelial-Mesenchymal Transition.
Zou J, Huang R, Chen Y, Huang X, Li H, Liang P, Chen S
Frontiers in cell and developmental biology 2021;9:641432
Frontiers in cell and developmental biology 2021;9:641432
High Serpin Family A Member 10 Expression Confers Platinum Sensitivity and Is Associated With Survival Benefit in High-Grade Serous Ovarian Cancer: Based on Quantitative Proteomic Analysis.
Guo W, He X, Ni J, Ma L, Cheng X, Wang C, Chen X, Wang Y
Frontiers in oncology 2021;11:761960
Frontiers in oncology 2021;11:761960
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
Wang Y, Wei Q, Chen Y, Long S, Yao Y, Fu K
Frontiers in oncology 2021;11:604315
Frontiers in oncology 2021;11:604315
HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target.
Liu L, Zhang J, Zhang X, Cheng P, Liu L, Huang Q, Liu H, Ren S, Wei P, Wang C, Dou C, Chen L, Liu X, Zhang H, Chen M
Journal of molecular medicine (Berlin, Germany) 2021 Jan;99(1):107-118
Journal of molecular medicine (Berlin, Germany) 2021 Jan;99(1):107-118
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ
Nature cell biology 2021 Dec;23(12):1240-1254
Nature cell biology 2021 Dec;23(12):1240-1254
MiR-21-5p Induces Pyroptosis in Colorectal Cancer via TGFBI.
Jiang R, Chen X, Ge S, Wang Q, Liu Y, Chen H, Xu J, Wu J
Frontiers in oncology 2020;10:610545
Frontiers in oncology 2020;10:610545
Raloxifene and n-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa.
Aguado T, García M, García A, Ferrer-Mayorga G, Martínez-Santamaría L, Del Río M, Botella LM, Sánchez-Puelles JM
Cells 2020 Sep 16;9(9)
Cells 2020 Sep 16;9(9)
High Stromal TGFBI in Lung Cancer and Intratumoral CD8-Positive T Cells were Associated with Poor Prognosis and Therapeutic Resistance to Immune Checkpoint Inhibitors.
Nakazawa N, Yokobori T, Kaira K, Turtoi A, Baatar S, Gombodorj N, Handa T, Tsukagoshi M, Ubukata Y, Kimura A, Kogure N, Ogata K, Maeno T, Sohda M, Yajima T, Shimizu K, Mogi A, Kuwano H, Saeki H, Shirabe K
Annals of surgical oncology 2020 Mar;27(3):933-942
Annals of surgical oncology 2020 Mar;27(3):933-942
Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia.
Park HH, Kim HN, Kim H, Yoo Y, Shin H, Choi EY, Bae JS, Lee W
Science advances 2020 Jul;6(31)
Science advances 2020 Jul;6(31)
Dual peptide-dendrimer conjugate inhibits acetylation of transforming growth factor β-induced protein and improves survival in sepsis.
Lee W, Park EJ, Kwon OK, Kim H, Yoo Y, Kim SW, Seo YK, Kim IS, Na DH, Bae JS
Biomaterials 2020 Jul;246:120000
Biomaterials 2020 Jul;246:120000
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Kitamoto K, Taketani Y, Fujii W, Inamochi A, Toyono T, Miyai T, Yamagami S, Kuroda M, Usui T, Ouchi Y
Scientific reports 2020 Feb 6;10(1):2000
Scientific reports 2020 Feb 6;10(1):2000
Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C.
Steitz AM, Steffes A, Finkernagel F, Unger A, Sommerfeld L, Jansen JM, Wagner U, Graumann J, Müller R, Reinartz S
Cell death & disease 2020 Apr 20;11(4):249
Cell death & disease 2020 Apr 20;11(4):249
Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer.
Zhu H, Chen H, Wang J, Zhou L, Liu S
OncoTargets and therapy 2019;12:3441-3457
OncoTargets and therapy 2019;12:3441-3457
Secreted TGF-beta-induced protein promotes aggressive progression in bladder cancer cells.
Zou J, Huang R, Li H, Wang B, Chen Y, Chen S, Ou K, Wang X
Cancer management and research 2019;11:6995-7006
Cancer management and research 2019;11:6995-7006
TGFBI Promotes Tumor Growth and is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma.
Wang BJ, Chi KP, Shen RL, Zheng SW, Guo Y, Li JF, Fei J, He Y
Journal of Cancer 2019;10(20):4902-4912
Journal of Cancer 2019;10(20):4902-4912
PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia.
Zhang X, Liu L, Dou C, Cheng P, Liu L, Liu H, Ren S, Wang C, Jia S, Chen L, Zhang H, Chen M
Molecular therapy. Nucleic acids 2019 Sep 6;17:678-687
Molecular therapy. Nucleic acids 2019 Sep 6;17:678-687
TGFBI Protein Is Increased in the Urine of Patients with High-Grade Urothelial Carcinomas, and Promotes Cell Proliferation and Migration.
Lang K, Kahveci S, Bonberg N, Wichert K, Behrens T, Hovanec J, Roghmann F, Noldus J, Tam YC, Tannapfel A, Käfferlein HU, Brüning T
International journal of molecular sciences 2019 Sep 11;20(18)
International journal of molecular sciences 2019 Sep 11;20(18)
Collagen fiber changes related to keratoconus with secondary corneal amyloidosis.
Araki-Sasaki K, Osakabe Y, Fujita K, Miyata K, Hirano K
International medical case reports journal 2018;11:193-199
International medical case reports journal 2018;11:193-199
High stromal transforming growth factor β-induced expression is a novel marker of progression and poor prognosis in gastric cancer.
Suzuki M, Yokobori T, Gombodorj N, Yashiro M, Turtoi A, Handa T, Ogata K, Oyama T, Shirabe K, Kuwano H
Journal of surgical oncology 2018 Nov;118(6):966-974
Journal of surgical oncology 2018 Nov;118(6):966-974
Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line.
Sato T, Muramatsu T, Tanabe M, Inazawa J
Cancer science 2018 Nov;109(11):3623-3633
Cancer science 2018 Nov;109(11):3623-3633
c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer.
He H, Sinha I, Fan R, Haldosen LA, Yan F, Zhao C, Dahlman-Wright K
Oncogene 2018 May;37(19):2586-2600
Oncogene 2018 May;37(19):2586-2600
BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation.
Pan T, Lin SC, Yu KJ, Yu G, Song JH, Lewis VO, Bird JE, Moon B, Lin PP, Tannir NM, Jonasch E, Wood CG, Gallick GE, Yu-Lee LY, Lin SH, Satcher RL
Neoplasia (New York, N.Y.) 2018 Jan;20(1):32-43
Neoplasia (New York, N.Y.) 2018 Jan;20(1):32-43
Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.
Kontostathi G, Zoidakis J, Makridakis M, Lygirou V, Mermelekas G, Papadopoulos T, Vougas K, Vlamis-Gardikas A, Drakakis P, Loutradis D, Vlahou A, Anagnou NP, Pappa KI
BioMed research international 2017;2017:4180703
BioMed research international 2017;2017:4180703
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury.
Schwanekamp JA, Lorts A, Sargent MA, York AJ, Grimes KM, Fischesser DM, Gokey JJ, Whitsett JA, Conway SJ, Molkentin JD
PloS one 2017;12(7):e0181945
PloS one 2017;12(7):e0181945
Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer.
Chen WY, Tsai YC, Yeh HL, Suau F, Jiang KC, Shao AN, Huang J, Liu YN
Science signaling 2017 Aug 15;10(492)
Science signaling 2017 Aug 15;10(492)
Clinical implications of transforming growth factor-beta-induced gene-h3 protein expression in lung cancer.
He C, Sun D, Bai X, Li Y, Xu H, Xu S
OncoTargets and therapy 2016;9:4983-7
OncoTargets and therapy 2016;9:4983-7
New histopathologic and ultrastructural findings in Reis-Bücklers corneal dystrophy caused by the Arg124Leu mutation of TGFBI gene.
Qiu WY, Zheng LB, Pan F, Wang BB, Yao YF
BMC ophthalmology 2016 Sep 2;16(1):158
BMC ophthalmology 2016 Sep 2;16(1):158
Comparative proteomic analysis of extracellular secreted proteins expressed by two pathogenic Acanthamoeba castellanii clinical isolates and a non-pathogenic ATCC strain.
Huang JM, Lin WC, Li SC, Shih MH, Chan WC, Shin JW, Huang FC
Experimental parasitology 2016 Jul;166:60-7
Experimental parasitology 2016 Jul;166:60-7
TGFBI Expression in Cancer Stromal Cells is Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma.
Ozawa D, Yokobori T, Sohda M, Sakai M, Hara K, Honjo H, Kato H, Miyazaki T, Kuwano H
Annals of surgical oncology 2016 Jan;23(1):282-9
Annals of surgical oncology 2016 Jan;23(1):282-9
Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia.
Ahlfeld SK, Wang J, Gao Y, Snider P, Conway SJ
The American journal of pathology 2016 Apr;186(4):777-93
The American journal of pathology 2016 Apr;186(4):777-93
Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2.
Yamazoe K, Yoshida S, Yasuda M, Hatou S, Inagaki E, Ogawa Y, Tsubota K, Shimmura S
PloS one 2015;10(7):e0133397
PloS one 2015;10(7):e0133397
ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells.
Mężyk-Kopeć R, Wyroba B, Stalińska K, Próchnicki T, Wiatrowska K, Kilarski WW, Swartz MA, Bereta J
PloS one 2015;10(7):e0132661
PloS one 2015;10(7):e0132661
Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury.
Lim SW, Jin L, Piao SG, Chung BH, Yang CW
Laboratory investigation; a journal of technical methods and pathology 2015 Oct;95(10):1174-85
Laboratory investigation; a journal of technical methods and pathology 2015 Oct;95(10):1174-85
Tgfbi/Bigh3 silencing activates ERK in mouse retina.
Allaman-Pillet N, Oberson A, Bustamante M, Tasinato A, Hummler E, Schorderet DF
Experimental eye research 2015 Nov;140:159-170
Experimental eye research 2015 Nov;140:159-170
The role of TGFBI (βig-H3) in gastrointestinal tract tumorigenesis.
Han B, Cai H, Chen Y, Hu B, Luo H, Wu Y, Wu J
Molecular cancer 2015 Mar 24;14:64
Molecular cancer 2015 Mar 24;14:64
Identification and validation of TGFBI as a promising prognosis marker of clear cell renal cell carcinoma.
Lebdai S, Verhoest G, Parikh H, Jacquet SF, Bensalah K, Chautard D, Rioux Leclercq N, Azzouzi AR, Bigot P
Urologic oncology 2015 Feb;33(2):69.e11-8
Urologic oncology 2015 Feb;33(2):69.e11-8
Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues.
Kobayashi M, Nagashio R, Ryuge S, Murakami Y, Yanagita K, Nakashima H, Matsumoto T, Jiang SX, Saegusa M, Satoh Y, Masuda N, Sato Y
Biomedical research (Tokyo, Japan) 2014;35(2):133-43
Biomedical research (Tokyo, Japan) 2014;35(2):133-43
TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients.
Pajares MJ, Agorreta J, Salvo E, Behrens C, Wistuba II, Montuenga LM, Pio R, Rouzaut A
British journal of cancer 2014 Mar 18;110(6):1545-51
British journal of cancer 2014 Mar 18;110(6):1545-51
TGF-β-induced (TGFBI) protein in melanoma: a signature of high metastatic potential.
Lauden L, Siewiera J, Boukouaci W, Ramgolam K, Mourah S, Lebbe C, Charron D, Aoudjit F, Jabrane-Ferrat N, Al-Daccak R
The Journal of investigative dermatology 2014 Jun;134(6):1675-1685
The Journal of investigative dermatology 2014 Jun;134(6):1675-1685
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.
Zhu M, Chen Q, Liu X, Sun Q, Zhao X, Deng R, Wang Y, Huang J, Xu M, Yan J, Yu J
The FEBS journal 2014 Aug;281(16):3766-75
The FEBS journal 2014 Aug;281(16):3766-75
Ginseng treatment attenuates chronic cyclosporine nephropathy via reducing oxidative stress in an experimental mouse model.
Doh KC, Lim SW, Piao SG, Jin L, Heo SB, Zheng YF, Bae SK, Hwang GH, Min KI, Chung BH, Yang CW
American journal of nephrology 2013;37(5):421-33
American journal of nephrology 2013;37(5):421-33
Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model.
Kim DW, Walker RL, Meltzer PS, Cheng SY
Carcinogenesis 2013 Oct;34(10):2389-400
Carcinogenesis 2013 Oct;34(10):2389-400
Construction of eukaryotic plasmid expressing human TGFBI and its influence on human corneal epithelial cells.
Niu JY, Liu J, Liu L, Lü YY, Chen JS, Xu JT, Zhong JX
International journal of ophthalmology 2012;5(1):38-44
International journal of ophthalmology 2012;5(1):38-44
A unique TGFBI protein in granular corneal dystrophy types 1 and 2.
Han YP, Sim AJ, Vora SC, Huang AJ
Current eye research 2012 Nov;37(11):990-6
Current eye research 2012 Nov;37(11):990-6
Matrix metalloproteinase 9 (MMP-9)-dependent processing of βig-h3 protein regulates cell migration, invasion, and adhesion.
Kim YH, Kwon HJ, Kim DS
The Journal of biological chemistry 2012 Nov 9;287(46):38957-69
The Journal of biological chemistry 2012 Nov 9;287(46):38957-69
Role of leukotriene B₄ receptor signaling in human preadipocyte differentiation.
Hirata K, Katayama K, Nakajima A, Takada K, Kamisaki Y, Wada K
Biochemical and biophysical research communications 2012 Dec 14;429(3-4):197-203
Biochemical and biophysical research communications 2012 Dec 14;429(3-4):197-203
Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells.
Nummela P, Lammi J, Soikkeli J, Saksela O, Laakkonen P, Hölttä E
The American journal of pathology 2012 Apr;180(4):1663-74
The American journal of pathology 2012 Apr;180(4):1663-74
Unique TGFBI protein in lattice corneal dystrophy.
Han YP, Sim AJ, Vora SC, Huang AJ
Investigative ophthalmology & visual science 2011 Oct 28;52(11):8401-6
Investigative ophthalmology & visual science 2011 Oct 28;52(11):8401-6
Analysis of the human pancreatic stellate cell secreted proteome.
Wehr AY, Furth EE, Sangar V, Blair IA, Yu KH
Pancreas 2011 May;40(4):557-66
Pancreas 2011 May;40(4):557-66
Novel CHST6 gene mutations in 2 unrelated cases of macular corneal dystrophy.
Patel DA, Harocopos GJ, Chang SH, Vora SC, Lubniewski AJ, Huang AJ
Cornea 2011 Jun;30(6):664-9
Cornea 2011 Jun;30(6):664-9
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
Patel DA, Chang SH, Harocopos GJ, Vora SC, Thang DH, Huang AJ
Cornea 2010 Nov;29(11):1215-22
Cornea 2010 Nov;29(11):1215-22
TGFBI expression is associated with a better response to chemotherapy in NSCLC.
Irigoyen M, Pajares MJ, Agorreta J, Ponz-Sarvisé M, Salvo E, Lozano MD, Pío R, Gil-Bazo I, Rouzaut A
Molecular cancer 2010 May 28;9:130
Molecular cancer 2010 May 28;9:130
Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma.
Lin B, Madan A, Yoon JG, Fang X, Yan X, Kim TK, Hwang D, Hood L, Foltz G
PloS one 2010 Apr 19;5(4):e10210
PloS one 2010 Apr 19;5(4):e10210
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
Ma C, Rong Y, Radiloff DR, Datto MB, Centeno B, Bao S, Cheng AW, Lin F, Jiang S, Yeatman TJ, Wang XF
Genes & development 2008 Feb 1;22(3):308-21
Genes & development 2008 Feb 1;22(3):308-21
Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer.
Walker G, MacLeod K, Williams AR, Cameron DA, Smyth JF, Langdon SP
Gynecologic oncology 2007 Sep;106(3):461-8
Gynecologic oncology 2007 Sep;106(3):461-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 10188-1-AP( BIGH3 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-BIGH3 (IP:10188-1-AP, 3ug; Detection:10188-1-AP 1:300) with HeLa cells lysate 1000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 10188-1-AP(BIGH3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 10188-1-AP(BIGH3 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 10188-1-AP(BIGH3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TGFBI / BIGH3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TGFBI / BIGH3. This antibody recognizes human,mouse,rat antigen. The TGFBI / BIGH3 antibody has been validated for the following applications: ELISA, IP, IHC, WB analysis.