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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB2052 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2052, RRID:AB_1674772
- Product name
- EPM2A monoclonal antibody, clone k2A3
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant EPM2A.
- Isotype
- IgG
- Antibody clone number
- k2A3
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo.
Relationship between glycogen accumulation and the laforin dual specificity phosphatase.
Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: exon 1 mutations associate with an early-onset cognitive deficit subphenotype.
Tagliabracci VS, Turnbull J, Wang W, Girard JM, Zhao X, Skurat AV, Delgado-Escueta AV, Minassian BA, Depaoli-Roach AA, Roach PJ
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 4;104(49):19262-6
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 4;104(49):19262-6
Relationship between glycogen accumulation and the laforin dual specificity phosphatase.
Wang W, Parker GE, Skurat AV, Raben N, DePaoli-Roach AA, Roach PJ
Biochemical and biophysical research communications 2006 Nov 24;350(3):588-92
Biochemical and biophysical research communications 2006 Nov 24;350(3):588-92
Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: exon 1 mutations associate with an early-onset cognitive deficit subphenotype.
Ganesh S, Delgado-Escueta AV, Suzuki T, Francheschetti S, Riggio C, Avanzini G, Rabinowicz A, Bohlega S, Bailey J, Alonso ME, Rasmussen A, Thomson AE, Ochoa A, Prado AJ, Medina MT, Yamakawa K
Human molecular genetics 2002 May 15;11(11):1263-71
Human molecular genetics 2002 May 15;11(11):1263-71
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Cell lysates of HeLa (lane 1) and 293T (lane 2) (20 ug) were resolved by SDS-PAGE and probed with EPM2A monoclonal antibody, clone k2A3 (Cat # MAB2052) (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
