Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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- Product number
- ABIN2454875 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibody
- Antibody type
- Monoclonal
- Antigen
- Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T Cell.
- Description
- Purified from mouse ascites fluids by affinity chromatography
- Reactivity
- Human, Mouse
- Host
- Mouse
- Epitope
- AA 250-550
- Isotype
- IgG
- Antibody clone number
- 2A2
- Vial size
- 100 μL
- Storage
- -20°C
Submitted references LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal.
CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro.
LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/β-catenin signaling pathway in colorectal cancer cells.
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis.
Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers.
PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages.
Shaikh LH, Zhou J, Teo AE, Garg S, Neogi SG, Figg N, Yeo GS, Yu H, Maguire JJ, Zhao W, Bennett MR, Azizan EA, Davenport AP, McKenzie G, Brown MJ
The Journal of clinical endocrinology and metabolism 2015 Jun;100(6):E836-44
The Journal of clinical endocrinology and metabolism 2015 Jun;100(6):E836-44
CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
Hsu HC, Liu YS, Tseng KC, Yang TS, Yeh CY, You JF, Hung HY, Chen SJ, Chen HC
Journal of cancer research and clinical oncology 2015 Jan;141(1):11-21
Journal of cancer research and clinical oncology 2015 Jan;141(1):11-21
Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro.
Wang J, Guo X, Lui M, Chu PJ, Yoo J, Chang M, Yen Y
PloS one 2014;9(1):e85112
PloS one 2014;9(1):e85112
LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/β-catenin signaling pathway in colorectal cancer cells.
Hsu HC, Liu YS, Tseng KC, Tan BC, Chen SJ, Chen HC
Cellular signalling 2014 Nov;26(11):2333-42
Cellular signalling 2014 Nov;26(11):2333-42
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis.
Jiang N, Zhou J, Chen M, Schiff MD, Lee CH, Kong K, Embree MC, Zhou Y, Mao JJ
Biomaterials 2014 Feb;35(7):2172-80
Biomaterials 2014 Feb;35(7):2172-80
Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers.
Wu C, Xie Y, Gao F, Wang Y, Guo Y, Tian H, Li Y, Fan W
Gene 2013 Aug 1;525(1):18-25
Gene 2013 Aug 1;525(1):18-25
PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages.
Pastò A, Marchesi M, Diamantini A, Frasson C, Curtarello M, Lago C, Pilotto G, Parenti AR, Esposito G, Agostini M, Nitti D, Amadori A
PloS one 2012;7(8):e43379
PloS one 2012;7(8):e43379
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