M00239

antibody from Boster Biological Technology
Targeting: LGR5 FEX, GPR49, GPR67, HG38
Provider product page for M00239
Western blot
Immunoprecipitation
Flow cytometry

Antibody data

Product number
M00239 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-LGR5/GPR49 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for GPR49/LGR5 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, WB. Reactive species: Human, Mouse, Rat GPR49/LGR5 information: Molecular Weight: 99998 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Rapidly and constitutively internalized to the trans-Golgi network at steady state. Internalization to the trans- Golgi network may be the result of phosphorylation at Ser-861 and Ser-864; however, the phosphorylation event has not been proven (PubMed:23439653); Tissue Specificity: Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Antibody clone number
CHF-12
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
LGR5 protein structure - M00239 shown in red.