Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- M00239 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-LGR5/GPR49 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for GPR49/LGR5 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, WB. Reactive species: Human, Mouse, Rat GPR49/LGR5 information: Molecular Weight: 99998 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Rapidly and constitutively internalized to the trans-Golgi network at steady state. Internalization to the trans- Golgi network may be the result of phosphorylation at Ser-861 and Ser-864; however, the phosphorylation event has not been proven (PubMed:23439653); Tissue Specificity: Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- CHF-12
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
No comments: Submit comment
No validations: Submit validation data