Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2839373 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 443-473, Center
- Antibody clone number
- RB14555
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling.
LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Judah D, Rudkouskaya A, Wilson R, Carter DE, Dagnino L
PloS one 2012;7(5):e36704
PloS one 2012;7(5):e36704
LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.
Walker F, Zhang HH, Odorizzi A, Burgess AW
PloS one 2011;6(7):e22733
PloS one 2011;6(7):e22733
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H
Nature 2007 Oct 25;449(7165):1003-7
Nature 2007 Oct 25;449(7165):1003-7
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Supportive validation
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- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC