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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 21833-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21833-1-AP, RRID:AB_11232417
- Product name
- LGR5 antibody
- Antibody type
- Polyclonal
- Description
- LGR5 antibody (Cat. #21833-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ZNF217-activated Notch signaling mediates sulforaphane-suppressed stem cell properties in colorectal cancer.
Elevated Expression of LGR5 and WNT Signaling Factors in Neuroblastoma Cells With Acquired Drug Resistance.
REGγ regulates hair cycle by activating Lgr5 positive hair follicle stem cells.
Overexpression of Cancer-Associated Stem Cell Gene OLFM4 in the Colonic Epithelium of Patients With Primary Sclerosing Cholangitis.
Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement.
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.
Expression and clinical significance of SALL4 and LGR5 in patients with lung cancer.
Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas.
Wang M, Tang L, Chen S, Wang L, Wu J, Zhong C, Li Y, Chen Y
The Journal of nutritional biochemistry 2024 Mar;125:109551
The Journal of nutritional biochemistry 2024 Mar;125:109551
Elevated Expression of LGR5 and WNT Signaling Factors in Neuroblastoma Cells With Acquired Drug Resistance.
Clark-Corrigall J, Myssina S, Michaelis M, Cinatl J Jr, Ahmed S, Carr-Wilkinson J
Cancer investigation 2023 Feb;41(2):173-182
Cancer investigation 2023 Feb;41(2):173-182
REGγ regulates hair cycle by activating Lgr5 positive hair follicle stem cells.
Gao X, Wang Q, Yuan L, Jiao C, Yu Y, Wang X, Xu P, Ma Y, Wu Y, Wu Z, Li L, Xiao J, Dang Y
Journal of dermatological science 2021 May;102(2):101-108
Journal of dermatological science 2021 May;102(2):101-108
Overexpression of Cancer-Associated Stem Cell Gene OLFM4 in the Colonic Epithelium of Patients With Primary Sclerosing Cholangitis.
Neyazi M, Bharadwaj SS, Bullers S, Varenyiova Z, Oxford IBD Cohort Study Investigators, Travis S, Arancibia-Cárcamo CV, Powrie F, Geremia A
Inflammatory bowel diseases 2021 Jul 27;27(8):1316-1327
Inflammatory bowel diseases 2021 Jul 27;27(8):1316-1327
Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement.
Ishibashi R, Yoshida S, Odawara N, Kishikawa T, Kondo R, Nakada A, Hakuta R, Takahara N, Tanaka E, Sekiba K, Seimiya T, Ohnaga T, Otsuka M, Koike K
Oncology letters 2019 Dec;18(6):6397-6404
Oncology letters 2019 Dec;18(6):6397-6404
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
Zhang F, Sun H, Zhang S, Yang X, Zhang G, Su T
Oncology research 2017 May 24;25(5):709-719
Oncology research 2017 May 24;25(5):709-719
LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.
Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PD, Malik K
Oncotarget 2015 Nov 24;6(37):40053-67
Oncotarget 2015 Nov 24;6(37):40053-67
Expression and clinical significance of SALL4 and LGR5 in patients with lung cancer.
Gautam AK, Wang C, Zeng J, Wang J, Lu J, Wei J, Huang G, Mo B, Luo M, Mo B
Oncology letters 2015 Dec;10(6):3629-3634
Oncology letters 2015 Dec;10(6):3629-3634
Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas.
Wang Y, Jiang CQ, Fan LF
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):6075-82
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):6075-82
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LGR5 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LGR5. This antibody recognizes human antigen. The LGR5 antibody has been validated for the following applications: ELISA, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human small intestine using 21833-1-AP(LGR5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
