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- References [16]
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- Western blot [1]
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- Product number
- 14410-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14410-1-AP, RRID:AB_2281638
- Product name
- TAB2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TAB2 antibody (Cat. #14410-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9.
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation.
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
BMSCs mediates endothelial cell autophagy by upregulating miR-155-5p to alleviate ventilator-induced lung injury.
TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
miR-155 and miR-146a collectively regulate meningitic Escherichia coli infection-mediated neuroinflammatory responses.
In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin.
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation.
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
An Interaction Landscape of Ubiquitin Signaling.
Sun W, Li X, Dong J, Zhou Y
Stem cell research 2024 Feb;74:103284
Stem cell research 2024 Feb;74:103284
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
Li Z, Liu B, Lambertsen KL, Clausen BH, Zhu Z, Du X, Xu Y, Poulsen FR, Halle B, Bonde C, Chen M, Wang X, Schlüter D, Huang J, Waisman A, Song W, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK
Molecular cell 2023 Oct 5;83(19):3421-3437.e11
Molecular cell 2023 Oct 5;83(19):3421-3437.e11
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation.
Chen Y, Lin W, Chen P, Ye B, Luo W, Wang X, Huang W, Wu G, Liang G
Phytotherapy research : PTR 2023 Mar;37(3):860-871
Phytotherapy research : PTR 2023 Mar;37(3):860-871
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Li Q, Li S, Xu C, Zhao J, Hou L, Jiang F, Zhu Z, Wang Y, Tian L
Cell biology and toxicology 2023 Jun;39(3):703-717
Cell biology and toxicology 2023 Jun;39(3):703-717
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
Wang L, Wang X, Chen Q, Wei Z, Xu X, Han D, Zhang Y, Chen Z, Liang Q
The ocular surface 2023 Apr;28:131-140
The ocular surface 2023 Apr;28:131-140
BMSCs mediates endothelial cell autophagy by upregulating miR-155-5p to alleviate ventilator-induced lung injury.
Lin X, Yu T, Luo J, Chen L, Liu Y, Xu J, Chen L, Lin Q, Bao Y, Xu L
Journal of biochemical and molecular toxicology 2022 Jul;36(7):e23060
Journal of biochemical and molecular toxicology 2022 Jul;36(7):e23060
TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells.
Zhou Y, Liao Y, Zhang C, Liu J, Wang W, Huang J, Du Q, Liu T, Zou Q, Huang H, Liu P, Ooi S, Chen R, Xia M, Jiang H, Xu M, Pan Y, Yao S
Stem cells international 2021;2021:6550388
Stem cells international 2021;2021:6550388
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
miR-155 and miR-146a collectively regulate meningitic Escherichia coli infection-mediated neuroinflammatory responses.
Yang B, Yang R, Xu B, Fu J, Qu X, Li L, Dai M, Tan C, Chen H, Wang X
Journal of neuroinflammation 2021 May 13;18(1):114
Journal of neuroinflammation 2021 May 13;18(1):114
In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin.
Sun X, Kang Y, Xue S, Zou J, Xu J, Tang D, Qin H
The Korean journal of internal medicine 2021 Mar;36(Suppl 1):S160-S169
The Korean journal of internal medicine 2021 Mar;36(Suppl 1):S160-S169
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
Kong X, Hu S, Yuan Y, Du Y, Zhu Z, Song Z, Lu S, Zhao C, Yan D
Journal of Cancer 2020;11(11):3357-3368
Journal of Cancer 2020;11(11):3357-3368
Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation.
Lin FL, Ho JD, Cheng YW, Chiou GCY, Yen JL, Chang HM, Lee TH, Hsiao G
Frontiers in pharmacology 2018;9:326
Frontiers in pharmacology 2018;9:326
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, Huang H, Huang W, Chen S
Nature communications 2018 Oct 22;9(1):4381
Nature communications 2018 Oct 22;9(1):4381
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
Hussain T, Zhao D, Shah SZA, Wang J, Yue R, Liao Y, Sabir N, Yang L, Zhou X
Frontiers in immunology 2017;8:1915
Frontiers in immunology 2017;8:1915
An Interaction Landscape of Ubiquitin Signaling.
Zhang X, Smits AH, van Tilburg GB, Jansen PW, Makowski MM, Ovaa H, Vermeulen M
Molecular cell 2017 Mar 2;65(5):941-955.e8
Molecular cell 2017 Mar 2;65(5):941-955.e8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 14410-1-AP(MAP3K7IP2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MAP3K7IP2 antibody 14410-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAB2. This antibody recognizes human,mouse,rat antigen. The TAB2 antibody has been validated for the following applications: ELISA, IHC, IF, WB, FC analysis.
