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- Antibody Data
- Antigen structure
- References [26]
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- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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- Product number
- 14410-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14410-1-AP, RRID:AB_2281638
- Product name
- TAB2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TAB2 antibody (Cat. #14410-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough.
Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy.
TAB2 Promotes Immune Escape and Chemoresistance Through NF-κB Pathway Activation in Cervical Cancer.
Long non-coding RNA OIP5-AS1 protects neurons from ischemia-reperfusion injury and inhibits neuronal apoptosis through TAB-2.
TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes.
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
MicroRNA hsa-let-7e-5p in hUC-MSC-EVs alleviates oral mucositis by targeting TAB2.
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9.
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation.
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
TAB2 Promotes the Biological Functions of Head and Neck Squamous Cell Carcinoma Cells via EMT and PI3K Pathway.
Promotion of nonalcoholic steatohepatitis by RNA N(6)-methyladenosine reader IGF2BP2 in mice.
BMSCs mediates endothelial cell autophagy by upregulating miR-155-5p to alleviate ventilator-induced lung injury.
TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
miR-155 and miR-146a collectively regulate meningitic Escherichia coli infection-mediated neuroinflammatory responses.
In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin.
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation.
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
An Interaction Landscape of Ubiquitin Signaling.
Su M, Zhang J, Wang S, Chen W, Lai M, Peng L, Liang Y, Feng Y, Zhou H, Qiao W, Sun P
Chinese medicine 2025 Oct 4;20(1):160
Chinese medicine 2025 Oct 4;20(1):160
Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy.
Shu B, Zou M, Liao R, Wen D, Gao X, Lu J, Song H, Sheng Z, Liu Z, You Y
Cancer cell international 2025 Nov 26;25(1):425
Cancer cell international 2025 Nov 26;25(1):425
TAB2 Promotes Immune Escape and Chemoresistance Through NF-κB Pathway Activation in Cervical Cancer.
Wu M, Zhang Y, Wang X, Zhou Y
Journal of cellular and molecular medicine 2025 Mar;29(6):e70522
Journal of cellular and molecular medicine 2025 Mar;29(6):e70522
Long non-coding RNA OIP5-AS1 protects neurons from ischemia-reperfusion injury and inhibits neuronal apoptosis through TAB-2.
Zhu X, Li S, Ding H, Li X, Li H, Sun Q
Biochemical and biophysical research communications 2025 Jan;743:151139
Biochemical and biophysical research communications 2025 Jan;743:151139
TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes.
Sun W, Zhang J, Li S, Fu W, Liu Y, Liu M, Dong J, Zhao X, Li X
Molecular medicine (Cambridge, Mass.) 2025 Feb 4;31(1):42
Molecular medicine (Cambridge, Mass.) 2025 Feb 4;31(1):42
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Zhang X, Su Y, Yang W, Song Z, Sun Z, Wu X, Chen J, Gao B, Wang Z, Wang L, Jiang Q, Bu L, Li J, Lin Y, Xie W, Li J, Guo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
MicroRNA hsa-let-7e-5p in hUC-MSC-EVs alleviates oral mucositis by targeting TAB2.
Lin S, Lai D, Tian Y, Lai F, Long M, Ji C, Hao G
Scandinavian journal of immunology 2024 Oct;100(4):e13399
Scandinavian journal of immunology 2024 Oct;100(4):e13399
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Li N, Yun B, Zeng L, Lv Y, Zhou Y, Fang M, Li S, Chen Y, Huang E, Zhang L, Jiang Y, Zhang H, Li J, Yuan X
Communications biology 2024 Oct 2;7(1):1246
Communications biology 2024 Oct 2;7(1):1246
Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9.
Sun W, Li X, Dong J, Zhou Y
Stem cell research 2024 Feb;74:103284
Stem cell research 2024 Feb;74:103284
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
Li Z, Liu B, Lambertsen KL, Clausen BH, Zhu Z, Du X, Xu Y, Poulsen FR, Halle B, Bonde C, Chen M, Wang X, Schlüter D, Huang J, Waisman A, Song W, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK
Molecular cell 2023 Oct 5;83(19):3421-3437.e11
Molecular cell 2023 Oct 5;83(19):3421-3437.e11
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation.
Chen Y, Lin W, Chen P, Ye B, Luo W, Wang X, Huang W, Wu G, Liang G
Phytotherapy research : PTR 2023 Mar;37(3):860-871
Phytotherapy research : PTR 2023 Mar;37(3):860-871
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Li Q, Li S, Xu C, Zhao J, Hou L, Jiang F, Zhu Z, Wang Y, Tian L
Cell biology and toxicology 2023 Jun;39(3):703-717
Cell biology and toxicology 2023 Jun;39(3):703-717
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
Wang L, Wang X, Chen Q, Wei Z, Xu X, Han D, Zhang Y, Chen Z, Liang Q
The ocular surface 2023 Apr;28:131-140
The ocular surface 2023 Apr;28:131-140
TAB2 Promotes the Biological Functions of Head and Neck Squamous Cell Carcinoma Cells via EMT and PI3K Pathway.
Liu H, Zhang H, Fan H, Tang S, Weng J
Disease markers 2022;2022:1217918
Disease markers 2022;2022:1217918
Promotion of nonalcoholic steatohepatitis by RNA N(6)-methyladenosine reader IGF2BP2 in mice.
Zhou B, Luo Y, Ji N, Mao F, Xiang L, Bian H, Zheng MH, Hu C, Li Y, Lu Y
Life metabolism 2022 Oct;1(2):161-174
Life metabolism 2022 Oct;1(2):161-174
BMSCs mediates endothelial cell autophagy by upregulating miR-155-5p to alleviate ventilator-induced lung injury.
Lin X, Yu T, Luo J, Chen L, Liu Y, Xu J, Chen L, Lin Q, Bao Y, Xu L
Journal of biochemical and molecular toxicology 2022 Jul;36(7):e23060
Journal of biochemical and molecular toxicology 2022 Jul;36(7):e23060
TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells.
Zhou Y, Liao Y, Zhang C, Liu J, Wang W, Huang J, Du Q, Liu T, Zou Q, Huang H, Liu P, Ooi S, Chen R, Xia M, Jiang H, Xu M, Pan Y, Yao S
Stem cells international 2021;2021:6550388
Stem cells international 2021;2021:6550388
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
miR-155 and miR-146a collectively regulate meningitic Escherichia coli infection-mediated neuroinflammatory responses.
Yang B, Yang R, Xu B, Fu J, Qu X, Li L, Dai M, Tan C, Chen H, Wang X
Journal of neuroinflammation 2021 May 13;18(1):114
Journal of neuroinflammation 2021 May 13;18(1):114
In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin.
Sun X, Kang Y, Xue S, Zou J, Xu J, Tang D, Qin H
The Korean journal of internal medicine 2021 Mar;36(Suppl 1):S160-S169
The Korean journal of internal medicine 2021 Mar;36(Suppl 1):S160-S169
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
Kong X, Hu S, Yuan Y, Du Y, Zhu Z, Song Z, Lu S, Zhao C, Yan D
Journal of Cancer 2020;11(11):3357-3368
Journal of Cancer 2020;11(11):3357-3368
Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation.
Lin FL, Ho JD, Cheng YW, Chiou GCY, Yen JL, Chang HM, Lee TH, Hsiao G
Frontiers in pharmacology 2018;9:326
Frontiers in pharmacology 2018;9:326
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, Huang H, Huang W, Chen S
Nature communications 2018 Oct 22;9(1):4381
Nature communications 2018 Oct 22;9(1):4381
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
Hussain T, Zhao D, Shah SZA, Wang J, Yue R, Liao Y, Sabir N, Yang L, Zhou X
Frontiers in immunology 2017;8:1915
Frontiers in immunology 2017;8:1915
An Interaction Landscape of Ubiquitin Signaling.
Zhang X, Smits AH, van Tilburg GB, Jansen PW, Makowski MM, Ovaa H, Vermeulen M
Molecular cell 2017 Mar 2;65(5):941-955.e8
Molecular cell 2017 Mar 2;65(5):941-955.e8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 14410-1-AP(MAP3K7IP2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MAP3K7IP2 antibody 14410-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAB2. This antibody recognizes human,mouse,rat antigen. The TAB2 antibody has been validated for the following applications: ELISA, IHC, IF, WB, FC analysis.
