CABT-BL3497

antibody from Creative Diagnostics

Targeting: TAB2 KIAA0733, MAP3K7IP2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL3497

Provider

Creative Diagnostics

Product name

Anti-TAB2 (N-terminal) polyclonal antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at +4°C or -20°C long term. Avoid repeated freeze / thaw cycles. Store undiluted.