Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx011864 - Provider product page
- Provider
- Abbexa
- Product name
- TGF-Beta-Activated Kinase 1 And MAP3K7-Binding Protein 2 (TAB2) Antibody
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappa B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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