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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA052701 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA052701, RRID:AB_2681921
- Product name
- Anti-CEL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CEL, Gene description: carboxyl ester lipase, Alternative Gene Names: BSSL, MODY8, Validated applications: IHC, Uniprot ID: , Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.05 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants
Brekke R, Gravdal A, El Jellas K, Curry G, Lin J, Wilhelm S, Steine S, Mas E, Johansson S, Lowe M, Johansson B, Xiao X, Fjeld K, Molven A
Human Molecular Genetics 2024;33(11):1001-1014
Human Molecular Genetics 2024;33(11):1001-1014
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Fjeld K, Gravdal A, Brekke R, Alam J, Wilhelm S, El Jellas K, Pettersen H, Lin J, Solheim M, Steine S, Johansson B, Njølstad P, Verbeke C, Xiao X, Lowe M, Molven A
Pancreatology 2022;22(8):1099-1111
Pancreatology 2022;22(8):1099-1111
Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells
Dalva M, Lavik I, El Jellas K, Gravdal A, Lugea A, Pandol S, Njølstad P, Waldron R, Fjeld K, Johansson B, Molven A
Cells 2020;9(1):244
Cells 2020;9(1):244
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants
El Jellas K, Johansson B, Fjeld K, Antonopoulos A, Immervoll H, Choi M, Hoem D, Lowe M, Lombardo D, Njølstad P, Dell A, Mas E, Haslam S, Molven A
Journal of Biological Chemistry 2018;293(50):19476-19491
Journal of Biological Chemistry 2018;293(50):19476-19491
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human pancreas and liver tissues using HPA052701 antibody. Corresponding CEL RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
