10394-1-AP
antibody from Proteintech Group
Targeting: CFLAR
c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT
Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 10394-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10394-1-AP, RRID:AB_2081087
- Product name
- CFLAR/FLIP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CFLAR/FLIP antibody (Cat. #10394-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer.
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats.
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation.
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis.
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Miller AL, Perurena N, Gardner A, Hinoue T, Loi P, Laird PW, Cichowski K
Cancer research 2023 Jun 2;83(11):1800-1814
Cancer research 2023 Jun 2;83(11):1800-1814
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Tan J, Sun M, Yin J, Zhou Q, Zhao R, Chen Q, Sun H, Jiang C, Li S, He Y
Chemico-biological interactions 2022 Dec 1;368:110208
Chemico-biological interactions 2022 Dec 1;368:110208
Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats.
Zhang Y, Ye T, Zhou P, Li R, Liu Z, Xie J, Hua T, Sun Q
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Huangfu J, Hao C, Wei Z, Wormstone IM, Yan H, Fan X
Cell death & disease 2021 Apr 9;12(4):386
Cell death & disease 2021 Apr 9;12(4):386
YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation.
Chandrasekaran AP, Poondla N, Ko NR, Oh SJ, Ramakrishna S
Oncology letters 2020 Oct;20(4):72
Oncology letters 2020 Oct;20(4):72
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, Gu M, Yang W
Molecular medicine reports 2020 Feb;21(2):936-944
Molecular medicine reports 2020 Feb;21(2):936-944
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis.
Poondla N, Chandrasekaran AP, Heese K, Kim KS, Ramakrishna S
Biochemical and biophysical research communications 2019 Apr 23;512(1):60-65
Biochemical and biophysical research communications 2019 Apr 23;512(1):60-65
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Fitzsimmons L, Boyce AJ, Wei W, Chang C, Croom-Carter D, Tierney RJ, Herold MJ, Bell AI, Strasser A, Kelly GL, Rowe M
Cell death and differentiation 2018 Feb;25(2):241-254
Cell death and differentiation 2018 Feb;25(2):241-254
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Zhang X, Jiang SJ, Shang B, Jiang HJ
Thoracic cancer 2015 Mar;6(2):202-8
Thoracic cancer 2015 Mar;6(2):202-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10394-1-AP(CFLAR antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CFLAR/FLIP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CFLAR/FLIP. This antibody recognizes human antigen. The CFLAR/FLIP antibody has been validated for the following applications: ELISA, WB, IHC analysis.