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LearnABIN499850
antibody from antibodies-online
Targeting: CFLAR
c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN499850 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Human FLIP (C-Terminus) Peptide (ABIN499849)
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references Casper is a FADD- and caspase-related inducer of apoptosis.
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.
Inhibition of death receptor signals by cellular FLIP.
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
Shu HB, Halpin DR, Goeddel DV
Immunity 1997 Jun;6(6):751-63
Immunity 1997 Jun;6(6):751-63
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.
Hu S, Vincenz C, Ni J, Gentz R, Dixit VM
The Journal of biological chemistry 1997 Jul 11;272(28):17255-7
The Journal of biological chemistry 1997 Jul 11;272(28):17255-7
Inhibition of death receptor signals by cellular FLIP.
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J
Nature 1997 Jul 10;388(6638):190-5
Nature 1997 Jul 10;388(6638):190-5
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schröter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J
Nature 1997 Apr 3;386(6624):517-21
Nature 1997 Apr 3;386(6624):517-21
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of FLIP in total cell lysates from HeLa (H), Jurkat (J), THP-1 (T), A431 (A), K562 (K) and NIH3T3 (N) cells with AP30343PU-N FLIP antibody at 1/1000 dilution.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry staining of HeLa cells using AP30343PU-N FLIP antibody at 2 ?g/ml.
