ABIN318973

antibody from antibodies-online

Targeting: CFLAR c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN318973

Provider

antibodies-online

Product name

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 191-209), (C-Term) antibody

Antibody type

Polyclonal

Description

Purified

Reactivity

Human, Mouse

Host

Rabbit

Epitope

C-Term, AA 191-209

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Casper is a FADD- and caspase-related inducer of apoptosis.

Shu HB, Halpin DR, Goeddel DV
Immunity 1997 Jun;6(6):751-63

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I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.

Hu S, Vincenz C, Ni J, Gentz R, Dixit VM
The Journal of biological chemistry 1997 Jul 11;272(28):17255-7

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Inhibition of death receptor signals by cellular FLIP.

Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J
Nature 1997 Jul 10;388(6638):190-5

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.

Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schröter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J
Nature 1997 Apr 3;386(6624):517-21