Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8722 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- EAF2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- ELL-associated factor 2; Testosterone-regulated apoptosis inducer and tumor suppressor protein; EAF2; TRAITS; BM-040
- Description
- EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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