RA0263

antibody from Oursmab

Targeting: FZD7 FzE3

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0263

Provider

Oursmab

Product name

Vantictumab (Biosimilar Reference Antibody) (FZD)

Antibody type

Monoclonal

Description

Vantictumab is a humanized monoclonal antibody targeting Frizzled receptors (FZD1, 2, 5, 7, 8), key components of the Wnt signaling pathway. It binds to multiple FZD receptors to inhibit Wnt/¦Â-catenin signaling, which is often dysregulated in cancers. It was investigated for the treatment of solid tumors, such as pancreatic and breast cancers, but clinical development was discontinued due to bone-related toxicity and limited efficacy.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.