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Immunoprecipitation
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- Antibody Data
- Antigen structure
- References [20]
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- Product number
- GTX42128 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX42128, RRID:AB_11163958
- Product name
- CD28 antibody [YTH913.12]
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Rat
Submitted references The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages.
Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells.
Regulation of IL-17 in chronic inflammation in the human lung.
Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol.
Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease.
High rate of mutation reporter gene inactivation during human T cell proliferation.
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.
CD28 is not directly involved in the response of human CD3- CD56+ natural killer cells to lipopolysaccharide: a role for T cells.
Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire.
Induction of human T lymphocyte cytotoxicity and inhibition of tumor growth by tumor-specific diabody-based molecules secreted from gene-modified bystander cells.
Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis.
Human NK cell-mediated cytotoxicity triggered by CD86 and Gal alpha 1,3-Gal is inhibited in genetically modified porcine cells.
The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.
NK cell triggering by the human costimulatory molecules CD80 and CD86.
Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells.
IL-2-independent activation and proliferation in human T cells induced by CD28.
Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals.
Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95.
Characterization of tumor-infiltrating T lymphocytes in B-cell lymphomas of mucosa-associated lymphoid tissue.
Human T cell clones with gamma/delta and alpha/beta receptors are differently stimulated by monoclonal antibodies to CD2.
Svensson-Arvelund J, Mehta RB, Lindau R, Mirrasekhian E, Rodriguez-Martinez H, Berg G, Lash GE, Jenmalm MC, Ernerudh J
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1534-44
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1534-44
Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells.
Litjens NH, Boer K, Betjes MG
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1083-90
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1083-90
Regulation of IL-17 in chronic inflammation in the human lung.
Pridgeon C, Bugeon L, Donnelly L, Straschil U, Tudhope SJ, Fenwick P, Lamb JR, Barnes PJ, Dallman MJ
Clinical science (London, England : 1979) 2011 Jun;120(12):515-24
Clinical science (London, England : 1979) 2011 Jun;120(12):515-24
Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol.
Mjösberg J, Svensson J, Johansson E, Hellström L, Casas R, Jenmalm MC, Boij R, Matthiesen L, Jönsson JI, Berg G, Ernerudh J
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 1;183(1):759-69
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 1;183(1):759-69
Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease.
Verkade MA, van Druningen CJ, Vaessen LM, Hesselink DA, Weimar W, Betjes MG
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Jan;22(1):128-38
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Jan;22(1):128-38
High rate of mutation reporter gene inactivation during human T cell proliferation.
Gabdoulkhakova A, Henriksson G, Avkhacheva N, Sofin A, Bredberg A
Immunogenetics 2007 Feb;59(2):135-43
Immunogenetics 2007 Feb;59(2):135-43
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.
Kropf P, Baud D, Marshall SE, Munder M, Mosley A, Fuentes JM, Bangham CR, Taylor GP, Herath S, Choi BS, Soler G, Teoh T, Modolell M, Müller I
European journal of immunology 2007 Apr;37(4):935-45
European journal of immunology 2007 Apr;37(4):935-45
CD28 is not directly involved in the response of human CD3- CD56+ natural killer cells to lipopolysaccharide: a role for T cells.
Goodier MR, Londei M
Immunology 2004 Apr;111(4):384-90
Immunology 2004 Apr;111(4):384-90
Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire.
Battaglia A, Ferrandina G, Buzzonetti A, Malinconico P, Legge F, Salutari V, Scambia G, Fattorossi A
Immunology 2003 Nov;110(3):304-12
Immunology 2003 Nov;110(3):304-12
Induction of human T lymphocyte cytotoxicity and inhibition of tumor growth by tumor-specific diabody-based molecules secreted from gene-modified bystander cells.
Blanco B, Holliger P, Vile RG, Alvarez-Vallina L
Journal of immunology (Baltimore, Md. : 1950) 2003 Jul 15;171(2):1070-7
Journal of immunology (Baltimore, Md. : 1950) 2003 Jul 15;171(2):1070-7
Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis.
Ponchel F, Morgan AW, Bingham SJ, Quinn M, Buch M, Verburg RJ, Henwood J, Douglas SH, Masurel A, Conaghan P, Gesinde M, Taylor J, Markham AF, Emery P, van Laar JM, Isaacs JD
Blood 2002 Dec 15;100(13):4550-6
Blood 2002 Dec 15;100(13):4550-6
Human NK cell-mediated cytotoxicity triggered by CD86 and Gal alpha 1,3-Gal is inhibited in genetically modified porcine cells.
Costa C, Barber DF, Fodor WL
Journal of immunology (Baltimore, Md. : 1950) 2002 Apr 15;168(8):3808-16
Journal of immunology (Baltimore, Md. : 1950) 2002 Apr 15;168(8):3808-16
The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.
Chuang E, Fisher TS, Morgan RW, Robbins MD, Duerr JM, Vander Heiden MG, Gardner JP, Hambor JE, Neveu MJ, Thompson CB
Immunity 2000 Sep;13(3):313-22
Immunity 2000 Sep;13(3):313-22
NK cell triggering by the human costimulatory molecules CD80 and CD86.
Wilson JL, Charo J, Martín-Fontecha A, Dellabona P, Casorati G, Chambers BJ, Kiessling R, Bejarano MT, Ljunggren HG
Journal of immunology (Baltimore, Md. : 1950) 1999 Oct 15;163(8):4207-12
Journal of immunology (Baltimore, Md. : 1950) 1999 Oct 15;163(8):4207-12
Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells.
Galea-Lauri J, Darling D, Gan SU, Krivochtchapov L, Kuiper M, Gäken J, Souberbielle B, Farzaneh F
Journal of immunology (Baltimore, Md. : 1950) 1999 Jul 1;163(1):62-70
Journal of immunology (Baltimore, Md. : 1950) 1999 Jul 1;163(1):62-70
IL-2-independent activation and proliferation in human T cells induced by CD28.
Boulougouris G, McLeod JD, Patel YI, Ellwood CN, Walker LS, Sansom DM
Journal of immunology (Baltimore, Md. : 1950) 1999 Aug 15;163(4):1809-16
Journal of immunology (Baltimore, Md. : 1950) 1999 Aug 15;163(4):1809-16
Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals.
Kaga S, Ragg S, Rogers KA, Ochi A
Journal of immunology (Baltimore, Md. : 1950) 1998 May 1;160(9):4182-9
Journal of immunology (Baltimore, Md. : 1950) 1998 May 1;160(9):4182-9
Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95.
McLeod JD, Walker LS, Patel YI, Boulougouris G, Sansom DM
Journal of immunology (Baltimore, Md. : 1950) 1998 Mar 1;160(5):2072-9
Journal of immunology (Baltimore, Md. : 1950) 1998 Mar 1;160(5):2072-9
Characterization of tumor-infiltrating T lymphocytes in B-cell lymphomas of mucosa-associated lymphoid tissue.
Koulis A, Diss T, Isaacson PG, Dogan A
The American journal of pathology 1997 Nov;151(5):1353-60
The American journal of pathology 1997 Nov;151(5):1353-60
Human T cell clones with gamma/delta and alpha/beta receptors are differently stimulated by monoclonal antibodies to CD2.
Pawelec G, Schaudt K, Rehbein A, Olive D, Bühring HJ
Cellular immunology 1990 Sep;129(2):385-93
Cellular immunology 1990 Sep;129(2):385-93
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Rat anti Human CD28: Biotin (GTX76418)
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Rat anti Human CD28:RPE (GTX76421)
